Impaired granulopoiesis, myelodysplasia, and early lethality in CCAAT/enhancer binding protein epsilon-deficient mice. - Wikidata - thesis-toulmin - TriplyDB

Impaired granulopoiesis, myelodysplasia, and early lethality in CCAAT/enhancer binding protein epsilon-deficient mice.

Impaired granulopoiesis, myelodysplasia, and early lethality in CCAAT/enhancer binding protein epsilon-deficient mice.

http://www.wikidata.org/entity/Q36721547

about

CCAAT/enhancer-binding proteins: structure, function and regulation Upstream open reading frames: molecular switches in (patho)physiology EGO, a novel, noncoding RNA gene, regulates eosinophil granule protein transcript expression Neutrophil-specific granule deficiency results from a novel mutation with loss of function of the transcription factor CCAAT/enhancer binding protein epsilon Growth factor independence-1 (Gfi-1) plays a role in mediating specific granule deficiency (SGD) in a patient lacking a gene-inactivating mutation in the C/EBPepsilon gene Transcriptional activity of CCAAT/enhancer-binding proteins is controlled by a conserved inhibitory domain that is a target for sumoylation Novel combinatorial interactions of GATA-1, PU.1, and C/EBPepsilon isoforms regulate transcription of the gene encoding eosinophil granule major basic protein Inhibition of monocytic differentiation by phosphorylation-deficient Stat1 is associated with impaired expression of Stat2, ICSBP/IRF8 and C/EBPepsilon N-terminal region of CCAAT/enhancer-binding protein epsilon is critical for cell cycle arrest, apoptosis, and functional maturation during myeloid differentiation Impairment of natural killer cytotoxic activity and interferon gamma production in CCAAT/enhancer binding protein gamma-deficient mice Spi-B can functionally replace PU.1 in myeloid but not lymphoid development Genetic ablation of the CDP/Cux protein C terminus results in hair cycle defects and reduced male fertility Large-Scale Exome-wide Association Analysis Identifies Loci for White Blood Cell Traits and Pleiotropy with Immune-Mediated Diseases.Runx1 regulates embryonic myeloid fate choice in zebrafish through a negative feedback loop inhibiting Pu.1 expression Impaired neutrophil function in 24p3 null mice contributes to enhanced susceptibility to bacterial infections Reciprocal regulation of p63 by C/EBP delta in human keratinocytes.LPS independent activation of the pro-inflammatory receptor Trem1 by C/EBPε in granulocytes Expression profiling of differentiating eosinophils in bone marrow cultures predicts functional links between microRNAs and their target mRNAs.The C/EBP family of transcription factors in the liver and other organs.C/EBPepsilon directs granulocytic-vs-monocytic lineage determination and confers chemotactic function via Hlx.C/EBPδ gene targets in human keratinocytes.In vivo deficiency of both C/EBPβ and C/EBPε results in highly defective myeloid differentiation and lack of cytokine response.CCAAT/enhancer binding protein alpha is a regulatory switch sufficient for induction of granulocytic development from bipotential myeloid progenitors CCAAT/enhancer binding protein epsilon is a potential retinoid target gene in acute promyelocytic leukemia treatment.Regulation of eosinophil-specific gene expression by a C/EBP-Ets complex and GATA-1.Dichotomy of AML1-ETO functions: growth arrest versus block of differentiation What targeting eosinophils has taught us about their role in diseases.Posttranscriptional and posttranslational regulation of C/EBP delta in G0 growth-arrested mammary epithelial cells.STAT3 controls myeloid progenitor growth during emergency granulopoiesis.Function of RARalpha during the maturation of neutrophils.Crohn's disease: innate immunodeficiency?Modulation of DNA binding properties of CCAAT/enhancer binding protein epsilon by heterodimer formation and interactions with NFkappaB pathway.C/EBPε mediates nicotinamide-enhanced clearance of Staphylococcus aureus in mice.Neonatal sepsis and neutrophil insufficiencies Targets of the transcriptional repressor oncoprotein Gfi-1.Human α-defensin expression is not dependent on CCAAT/enhancer binding protein-ε in a murine model.The C/EBPbeta transcription factor regulates epithelial cell proliferation and differentiation in the mammary gland Distinct C/EBP functions are required for eosinophil lineage commitment and maturation Nicotinamide exacerbates hypoxemia in ventilator-induced lung injury independent of neutrophil infiltration.Immunogenetics. Chromatin state dynamics during blood formation

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Impaired granulopoiesis, myelodysplasia, and early lethality in CCAAT/enhancer binding protein epsilon-deficient mice.

http://www.wikidata.org/entity/Q36721547

description

1997 nî lūn-bûn

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1997年論文

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1997年論文

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1997年論文

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1997年論文

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1997年论文

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1997年论文

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1997年论文

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Impaired granulopoiesis, myelo ...... rotein epsilon-deficient mice.

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Impaired granulopoiesis, myelo ...... rotein epsilon-deficient mice.

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Impaired granulopoiesis, myelo ...... rotein epsilon-deficient mice.

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Impaired granulopoiesis, myelo ...... rotein epsilon-deficient mice.

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Impaired granulopoiesis, myelo ...... rotein epsilon-deficient mice.

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Proceedings of the National Academy of Sciences of the United States of America

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Impaired granulopoiesis, myelo ...... protein epsilon-deficient mice

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A Wynshaw-Boris

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A nuclear factor for IL-6 expression (NF-IL6) is a member of a C/EBP family

Immunodeficiency and chronic myelogenous leukemia-like syndrome in mice with a targeted mutation of the ICSBP gene

A novel human CCAAT/enhancer binding protein gene, C/EBPepsilon, is expressed in cells of lymphoid and myeloid lineages and is localized on chromosome 14q11.2 close to the T-cell receptor alpha/delta locus

Fibroblast growth factor receptor 3 is a negative regulator of bone growth

Cloning of the novel human myeloid-cell-specific C/EBP-epsilon transcription factor

CCAAT/enhancer binding protein epsilon is preferentially up-regulated during granulocytic differentiation and its functional versatility is determined by alternative use of promoters and differential splicing

Targeted disruption of the mouse transforming growth factor-beta 1 gene results in multifocal inflammatory disease

Lymphoproliferative disorders with early lethality in mice deficient in Ctla-4

Simplified mammalian DNA isolation procedure

Lymphoproliferation disorder in mice explained by defects in Fas antigen that mediates apoptosis

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