Human C/EBP-epsilon activator and repressor isoforms differentially reprogram myeloid lineage commitment and differentiation
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Upstream open reading frames: molecular switches in (patho)physiologyDevelopmental, malignancy-related, and cross-species analysis of eosinophil, mast cell, and basophil siglec-8 expressionNovel susceptibility variants at 10p12.31-12.2 for childhood acute lymphoblastic leukemia in ethnically diverse populationsExpression profiling of differentiating eosinophils in bone marrow cultures predicts functional links between microRNAs and their target mRNAs.C/EBPepsilon directs granulocytic-vs-monocytic lineage determination and confers chemotactic function via Hlx.In vivo deficiency of both C/EBPβ and C/EBPε results in highly defective myeloid differentiation and lack of cytokine response.What targeting eosinophils has taught us about their role in diseases.Association of genetic variation in IKZF1, ARID5B, and CEBPE and surrogates for early-life infections with the risk of acute lymphoblastic leukemia in Hispanic children.MicroRNA-150 expression induces myeloid differentiation of human acute leukemia cells and normal hematopoietic progenitorsHuman α-defensin expression is not dependent on CCAAT/enhancer binding protein-ε in a murine model.Eosinophils: changing perspectives in health and disease.Eosinophil development, regulation of eosinophil-specific genes, and role of eosinophils in the pathogenesis of asthmaWnt3a stimulates maturation of impaired neutrophils developed from severe congenital neutropenia patient-derived pluripotent stem cells.Novel targeted therapies for eosinophilic disordersGATA transcription factors regulate the expression of the human eosinophil-derived neurotoxin (RNase 2) gene.Respiratory viruses and eosinophils: exploring the connections.Regulation of monocyte differentiation by specific signaling modules and associated transcription factor networks.The Eosinophil in Health and Disease: from Bench to Bedside and Back.Transcription Factors in Eosinophil Development and As Therapeutic Targets.In vivo mutation of pre-mRNA processing factor 8 (Prpf8) affects transcript splicing, cell survival and myeloid differentiation.Expression characterization and the promoter activity analysis of zebrafish hdac4.Over-expression of Mcl-1 impairs the ability of ATRA to induce growth arrest and differentiation in acute promyelocytic leukemia cells.
P2860
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P2860
Human C/EBP-epsilon activator and repressor isoforms differentially reprogram myeloid lineage commitment and differentiation
description
article científic
@ca
article scientifique
@fr
articolo scientifico
@it
artigo científico
@pt
bilimsel makale
@tr
scientific article published on 02 October 2008
@en
vedecký článok
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vetenskaplig artikel
@sv
videnskabelig artikel
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vědecký článek
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name
Human C/EBP-epsilon activator ...... commitment and differentiation
@en
Human C/EBP-epsilon activator ...... ommitment and differentiation.
@nl
type
label
Human C/EBP-epsilon activator ...... commitment and differentiation
@en
Human C/EBP-epsilon activator ...... ommitment and differentiation.
@nl
prefLabel
Human C/EBP-epsilon activator ...... commitment and differentiation
@en
Human C/EBP-epsilon activator ...... ommitment and differentiation.
@nl
P2093
P2860
P1433
P1476
Human C/EBP-epsilon activator ...... commitment and differentiation
@en
P2093
Arun K Sharma
Ignatius Gomes
Richa Bedi
Steven J Ackerman
P2860
P304
P356
10.1182/BLOOD-2008-02-139741
P407
P577
2008-10-02T00:00:00Z