Parasite prolyl oligopeptidases and the challenge of designing chemotherapeuticals for Chagas disease, leishmaniasis and African trypanosomiasis
about
An essential signal peptide peptidase identified in an RNAi screen of serine peptidases of Trypanosoma bruceiProlyl Oligopeptidase from the Blood Fluke Schistosoma mansoni: From Functional Analysis to Anti-schistosomal InhibitorsThe endothelin system has a significant role in the pathogenesis and progression of Mycobacterium tuberculosis infection.The genome of Strongyloides spp. gives insights into protein families with a putative role in nematode parasitism.Identification of novel Trypanosoma cruzi prolyl oligopeptidase inhibitors by structure-based virtual screening.Insight into the Exoproteome of the Tissue-Derived Trypomastigote form of Trypanosoma cruzi.Prolyl oligopeptidase and its role in the organism: attention to the most promising and clinically relevant inhibitors.New compounds identified through in silico approaches reduce the α-synuclein expression by inhibiting prolyl oligopeptidase in vitro.Prolyl oligopeptidase-like deficient Trypanosoma evansi parasites are associated with reduced interleukin-10 concentrations in vivo and in vitro
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P2860
Parasite prolyl oligopeptidases and the challenge of designing chemotherapeuticals for Chagas disease, leishmaniasis and African trypanosomiasis
description
article científic
@ca
article scientifique
@fr
articolo scientifico
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artigo científico
@pt
bilimsel makale
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scientific article published on January 2013
@en
vedecký článok
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vetenskaplig artikel
@sv
videnskabelig artikel
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vědecký článek
@cs
name
Parasite prolyl oligopeptidase ...... is and African trypanosomiasis
@en
Parasite prolyl oligopeptidase ...... s and African trypanosomiasis.
@nl
type
label
Parasite prolyl oligopeptidase ...... is and African trypanosomiasis
@en
Parasite prolyl oligopeptidase ...... s and African trypanosomiasis.
@nl
prefLabel
Parasite prolyl oligopeptidase ...... is and African trypanosomiasis
@en
Parasite prolyl oligopeptidase ...... s and African trypanosomiasis.
@nl
P2093
P2860
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P1476
Parasite prolyl oligopeptidase ...... is and African trypanosomiasis
@en
P2093
I M D Bastos
J M Santana
P Grellier
P2860
P304
P356
10.2174/0929867311320250006
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P577
2013-01-01T00:00:00Z