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Loss of Ca(v)1.3 (CACNA1D) function in a human channelopathy with bradycardia and congenital deafnessMechanisms underlying the cardiac pacemaker: the role of SK4 calcium-activated potassium channelsHyperpolarization-activated current, If, in mathematical models of rabbit sinoatrial node pacemaker cellsModern concepts concerning the origin of the heartbeat.Small G proteins in the cardiovascular system: physiological and pathological aspectsEssential role of the m2R-RGS6-IKACh pathway in controlling intrinsic heart rate variabilitySimulation of Cardiac Arrhythmias Using a 2D Heterogeneous Whole Heart ModelIdentification and functional characterization of cardiac pacemaker cells in zebrafishCardiomyocyte Circadian Oscillations Are Cell-Autonomous, Amplified by β-Adrenergic Signaling, and Synchronized in Cardiac Ventricle TissueStructural Basis for the cAMP-dependent Gating in the Human HCN4 ChannelFrom Incidental, Mechanically-Induced Arrhythmias to Reflex-Defined Arrhythmogenicity: On The Track of The Ternary Reflex System Resemblance to The "Infancy" of New Era or RediscoveryThe importance of Ca(2+)-dependent mechanisms for the initiation of the heartbeatNeuronal T-type calcium channels: what's new? Iftinca: T-type channel regulationCardiac defects contribute to the pathology of spinal muscular atrophy modelsPopeye domain containing proteins are essential for stress-mediated modulation of cardiac pacemaking in miceGenetics of sick sinus syndromeHeart rate characteristics: physiomarkers for detection of late-onset neonatal sepsis.Pharmacodynamic effects of ivabradine, a negative chronotropic agent, in healthy cats.Deep bradycardia and heart block caused by inducible cardiac-specific knockout of the pacemaker channel gene Hcn4Direct conversion of quiescent cardiomyocytes to pacemaker cells by expression of Tbx18.Ca²⁺-dependent phosphorylation of Ca²⁺ cycling proteins generates robust rhythmic local Ca²⁺ releases in cardiac pacemaker cells.Paradoxical effect of increased diastolic Ca(2+) release and decreased sinoatrial node activity in a mouse model of catecholaminergic polymorphic ventricular tachycardia.G protein-gated IKACh channels as therapeutic targets for treatment of sick sinus syndrome and heart block.RyR2R420Q catecholaminergic polymorphic ventricular tachycardia mutation induces bradycardia by disturbing the coupled clock pacemaker mechanism.Connexin 30 is expressed in the mouse sino-atrial node and modulates heart rate.Molecular remodeling of ion channels, exchangers and pumps in atrial and ventricular myocytes in ischemic cardiomyopathy.I(f) and SR Ca(2+) release both contribute to pacemaker activity in canine sinoatrial node cellsA coupled SYSTEM of intracellular Ca2+ clocks and surface membrane voltage clocks controls the timekeeping mechanism of the heart's pacemaker.PP2 prevents β-adrenergic stimulation of cardiac pacemaker activity.Heart rhythm genomic fabric in hypoxiaCardiac sodium channelopathies.Phosphorylation and modulation of hyperpolarization-activated HCN4 channels by protein kinase A in the mouse sinoatrial nodeLipopolysaccharides directly decrease Ca2+ oscillations and the hyperpolarization-activated nonselective cation current If in immortalized HL-1 cardiomyocytes.Modulation by endothelin-1 of spontaneous activity and membrane currents of atrioventricular node myocytes from the rabbit heart.Novel oscillatory mechanisms in the cholinergic control of Guinea pig sino-atrial node discharge.Baf250a orchestrates an epigenetic pathway to repress the Nkx2.5-directed contractile cardiomyocyte program in the sinoatrial node.β-Adrenergic stimulation increases Cav3.1 activity in cardiac myocytes through protein kinase ACardiac arrhythmia induced by genetic silencing of 'funny' (f) channels is rescued by GIRK4 inactivationBK channels regulate sinoatrial node firing rate and cardiac pacing in vivoDistinct patterns of constitutive phosphodiesterase activity in mouse sinoatrial node and atrial myocardium.
P2860
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P2860
description
article científic
@ca
article scientifique
@fr
articolo scientifico
@it
artigo científico
@pt
bilimsel makale
@tr
scientific article published on July 2008
@en
vedecký článok
@sk
vetenskaplig artikel
@sv
videnskabelig artikel
@da
vědecký článek
@cs
name
Genesis and regulation of the heart automaticity.
@en
Genesis and regulation of the heart automaticity.
@nl
type
label
Genesis and regulation of the heart automaticity.
@en
Genesis and regulation of the heart automaticity.
@nl
prefLabel
Genesis and regulation of the heart automaticity.
@en
Genesis and regulation of the heart automaticity.
@nl
P2860
P1476
Genesis and regulation of the heart automaticity
@en
P2093
Joël Nargeot
Matteo E Mangoni
P2860
P304
P356
10.1152/PHYSREV.00018.2007
P577
2008-07-01T00:00:00Z