Adding an unnatural covalent bond to proteins through proximity-enhanced bioreactivity.
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Covalent agonists for studying G protein-coupled receptor activationGenetically encoded chemical probes in cells reveal the binding path of urocortin-I to CRF class B GPCRBioconjugation of therapeutic proteins and enzymes using the expanded set of genetically encoded amino acids.Genetically encoding photoswitchable click amino acids in Escherichia coli and mammalian cellsAt the Interface of Chemical and Biological Synthesis: An Expanded Genetic Code.A genetically encoded aza-Michael acceptor for covalent cross-linking of protein-receptor complexes.EMBO conference series: Chemical Biology 2014Enhancing protein stability with extended disulfide bonds.Cysteine Sulfoxidation Increases the Photostability of Red Fluorescent ProteinsIn Situ Formation of an Azo Bridge on Proteins Controllable by Visible Light.Proximity-enabled protein crosslinking through genetically encoding haloalkane unnatural amino acids.Structural insight into the activation of a class B G-protein-coupled receptor by peptide hormones in live human cells.Reduction-Responsive Guanine Incorporated into G-Quadruplex-Forming DNA.Guidelines for the Synthesis of Small-Molecule Irreversible Probes Targeting G Protein-Coupled Receptors.Genetically encoding new bioreactivity.Detection of protein-protein interactions by proximity-driven S(N)Ar reactions of lysine-linked fluorophores.Rewriting the Genetic Code.Site-Selective Modification of Proteins with Oxetanes.Genetically encoding an electrophilic amino acid for protein stapling and covalent binding to native receptors.Heritable expansion of the genetic code in mouse and zebrafish.Recombinant Macrocyclic Lanthipeptides Incorporating Non-Canonical Amino Acids.Engineering the Genetic Code in Cells and Animals: Biological Considerations and Impacts.Site-specific incorporation of phosphotyrosine using an expanded genetic code.Spontaneous and specific chemical cross-linking in live cells to capture and identify protein interactions.Proximity-Triggered Covalent Stabilization of Low-Affinity Protein Complexes In Vitro and In Vivo.Spirohexene-Tetrazine Ligation Enables Bioorthogonal Labeling of Class B G Protein-Coupled Receptors in Live Cells.Playing with the molecules of life.Palladium Oxidative Addition Complexes for Peptide and Protein Crosslinking.Protein Crosslinking by Genetically Encoded Noncanonical Amino Acids with Reactive Aryl Carbamate Side Chains.Genetic Incorporation of a Reactive Isothiocyanate Group into Proteins.Genetically Encoding Fluorosulfate-l-tyrosine To React with Lysine, Histidine, and Tyrosine via SuFEx in Proteins in Vivo.Oxidation-induced generation of a mild electrophile for proximity-enhanced protein-protein crosslinking.Efficient yeast surface-display of novel complex synthetic cellulosomesProximitäts-vermittelte kovalente Stabilisierung niedrig-affiner Proteinkomplexe in vitro und in vivo
P2860
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P2860
Adding an unnatural covalent bond to proteins through proximity-enhanced bioreactivity.
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article científic
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article scientifique
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articolo scientifico
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artigo científico
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bilimsel makale
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scientific article published on 04 August 2013
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vedecký článok
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vetenskaplig artikel
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videnskabelig artikel
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vědecký článek
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name
Adding an unnatural covalent bond to proteins through proximity-enhanced bioreactivity.
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Adding an unnatural covalent bond to proteins through proximity-enhanced bioreactivity.
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type
label
Adding an unnatural covalent bond to proteins through proximity-enhanced bioreactivity.
@en
Adding an unnatural covalent bond to proteins through proximity-enhanced bioreactivity.
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prefLabel
Adding an unnatural covalent bond to proteins through proximity-enhanced bioreactivity.
@en
Adding an unnatural covalent bond to proteins through proximity-enhanced bioreactivity.
@nl
P2093
P2860
P356
P1433
P1476
Adding an unnatural covalent bond to proteins through proximity-enhanced bioreactivity
@en
P2093
P2860
P2888
P304
P356
10.1038/NMETH.2595
P50
P577
2013-08-04T00:00:00Z