Endonuclease and Exonuclease Activities on Oligodeoxynucleotides Containing Spiroiminodihydantoin Depend on the Sequence Context and the Lesion Stereochemistry.
about
Reconciliation of chemical, enzymatic, spectroscopic and computational data to assign the absolute configuration of the DNA base lesion spiroiminodihydantoin.Spirodi(iminohydantoin) products from oxidation of 2'-deoxyguanosine in the presence of NH4Cl in nucleoside and oligodeoxynucleotide contexts.An ameliorative protocol for the quantification of purine 5',8-cyclo-2'-deoxynucleosides in oxidized DNA.Klenow Fragment Discriminates against the Incorporation of the Hyperoxidized dGTP Lesion Spiroiminodihydantoin into DNA.Formation and processing of DNA damage substrates for the hNEIL enzymes.8-Oxo-7,8-dihydro-2'-deoxyguanosine and abasic site tandem lesions are oxidation prone yielding hydantoin products that strongly destabilize duplex DNA.Interrogation of Base Pairing of the Spiroiminodihydantoin Diastereomers Using the α-Hemolysin Latch.
P2860
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P2860
Endonuclease and Exonuclease Activities on Oligodeoxynucleotides Containing Spiroiminodihydantoin Depend on the Sequence Context and the Lesion Stereochemistry.
description
2013 nî lūn-bûn
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Endonuclease and Exonuclease A ...... nd the Lesion Stereochemistry.
@en
Endonuclease and Exonuclease A ...... nd the Lesion Stereochemistry.
@nl
type
label
Endonuclease and Exonuclease A ...... nd the Lesion Stereochemistry.
@en
Endonuclease and Exonuclease A ...... nd the Lesion Stereochemistry.
@nl
prefLabel
Endonuclease and Exonuclease A ...... nd the Lesion Stereochemistry.
@en
Endonuclease and Exonuclease A ...... nd the Lesion Stereochemistry.
@nl
P2093
P2860
P356
P1476
Endonuclease and Exonuclease A ...... nd the Lesion Stereochemistry.
@en
P2093
Aaron M Fleming
Cynthia J Burrows
James G Muller
P2860
P304
P356
10.1039/C3NJ00418J
P577
2013-11-01T00:00:00Z