Pure Hemozoin is inflammatory in vivo and activates the NALP3 inflammasome via release of uric acid - Wikidata - thesis-toulmin - TriplyDB

Pure Hemozoin is inflammatory in vivo and activates the NALP3 inflammasome via release of uric acid

Pure Hemozoin is inflammatory in vivo and activates the NALP3 inflammasome via release of uric acid

http://www.wikidata.org/entity/Q39449735

about

Plasmodium falciparum histones induce endothelial proinflammatory response and barrier dysfunction Innate immune recognition of an AT-rich stem-loop DNA motif in the Plasmodium falciparum genome The inflammasome: in memory of Dr. Jurg Tschopp A Nod to disease vectors: mitigation of pathogen sensing by arthropod saliva An Update on PYRIN Domain-Containing Pattern Recognition Receptors: From Immunity to Pathology Insufficiently defined genetic background confounds phenotypes in transgenic studies as exemplified by malaria infection in Tlr9 knockout mice Reactive oxygen species-induced TXNIP drives fructose-mediated hepatic inflammation and lipid accumulation through NLRP3 inflammasome activation Tempol, an intracellular antioxidant, inhibits tissue factor expression, attenuates dendritic cell function, and is partially protective in a murine model of cerebral malaria.NLRP3 inflammasome plays a key role in the regulation of intestinal homeostasis.Hemozoin (malarial pigment) directly promotes apoptosis of erythroid precursors.A surprising role for uric acid: the inflammatory malaria response.The inflammasomes: mechanisms of activation and function.NLRP3 promotes autophagy of urate crystals phagocytized by human osteoblasts.Dual engagement of the NLRP3 and AIM2 inflammasomes by plasmodium-derived hemozoin and DNA during malaria Inflammasomes in host response to protozoan parasites.Quercetin and allopurinol ameliorate kidney injury in STZ-treated rats with regulation of renal NLRP3 inflammasome activation and lipid accumulation.Haemozoin induces early cytokine-mediated lysozyme release from human monocytes through p38 MAPK- and NF-kappaB-dependent mechanisms Xanthine oxidoreductase promotes the inflammatory state of mononuclear phagocytes through effects on chemokine expression, peroxisome proliferator-activated receptor-{gamma} sumoylation, and HIF-1{alpha}Hemozoin induces hepatic inflammation in mice and is differentially associated with liver pathology depending on the Plasmodium strain.Plasmodium falciparum-derived uric acid precipitates induce maturation of dendritic cells.A role for uric acid and the Nalp3 inflammasome in antiphospholipid antibody-induced IL-1β production by human first trimester trophoblast.Endothelial cells potentiate interferon-γ production in a novel tripartite culture model of human cerebral malaria.Natural haemozoin induces expression and release of human monocyte tissue inhibitor of metalloproteinase-1.Hemozoin activates the innate immune system and reduces Plasmodium berghei infection in Anopheles gambiae Differential induction of TLR3-dependent innate immune signaling by closely related parasite species.Natural hemozoin stimulates syncytiotrophoblast to secrete chemokines and recruit peripheral blood mononuclear cells.Exposure-dependent control of malaria-induced inflammation in children.NLRP3 inflammasome plays a critical role in the pathogenesis of hydroxyapatite-associated arthropathy.Xanthine oxidoreductase regulates macrophage IL1β secretion upon NLRP3 inflammasome activation.Interaction between uric acid and HMGB1 translocation and release from endothelial cells.TLR9 and MyD88 are crucial for the development of protective immunity to malaria.Opsonization of malaria-infected erythrocytes activates the inflammasome and enhances inflammatory cytokine secretion by human macrophages.Chlamydial plasmid-encoded protein pORF5 induces production of IL-1β and IL-18 via NALP3 inflammasome activation and p38 MAPK pathway.Particulate adjuvant and innate immunity: past achievements, present findings, and future prospects.NLR proteins and parasitic disease.Malaria-induced NLRP12/NLRP3-dependent caspase-1 activation mediates inflammation and hypersensitivity to bacterial superinfection.Malarial pigment hemozoin and the innate inflammatory response.Methemoglobin-induced signaling and chemokine responses in human alveolar epithelial cells Review of hyperuricemia as new marker for metabolic syndrome.Regulation of inflammasome activity.

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P2860

Pure Hemozoin is inflammatory in vivo and activates the NALP3 inflammasome via release of uric acid

http://www.wikidata.org/entity/Q39449735

description

2009 nî lūn-bûn

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2009年の論文

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2009年学术文章

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2009年学术文章

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2009年学术文章

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2009年学术文章

@zh-my

2009年学术文章

@zh-sg

2009年學術文章

@yue

2009年學術文章

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2009年學術文章

@zh-hant

name

Pure Hemozoin is inflammatory ...... asome via release of uric acid

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Pure Hemozoin is inflammatory ...... some via release of uric acid.

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type

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Pure Hemozoin is inflammatory ...... asome via release of uric acid

@en

Pure Hemozoin is inflammatory ...... some via release of uric acid.

@nl

prefLabel

Pure Hemozoin is inflammatory ...... asome via release of uric acid

@en

Pure Hemozoin is inflammatory ...... some via release of uric acid.

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Pure Hemozoin is inflammatory ...... asome via release of uric acid

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Michael T McIntosh

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Tiffany Sun

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P2860

A Toll-like receptor recognizes bacterial DNA

Toll-like receptor signalling

The global distribution of clinical episodes of Plasmodium falciparum malaria

Possible importance of macrophage-derived mediators in acute malaria

The Nalp3 inflammasome is essential for the development of silicosis

Innate immune activation through Nalp3 inflammasome sensing of asbestos and silica

Gout-associated uric acid crystals activate the NALP3 inflammasome

Role of adaptor TRIF in the MyD88-independent toll-like receptor signaling pathway

Toll-like receptor control of the adaptive immune responses

Signaling to NF-kappaB

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