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Ethanol Modulation is Quantitatively Determined by the Transmembrane Domain of Human α1 Glycine ReceptorsGeneral anesthetics predicted to block the GLIC pore with micromolar affinity.Phenylalanine in the pore of the Erwinia ligand-gated ion channel modulates picrotoxinin potency but not receptor functionMacroscopic kinetics of pentameric ligand gated ion channels: comparisons between two prokaryotic channels and one eukaryotic channel.The pharmacological profile of ELIC, a prokaryotic GABA-gated receptorPerturbation of Critical Prolines in Gloeobacter violaceus Ligand-gated Ion Channel (GLIC) Supports Conserved Gating Motions among Cys-loop Receptors.Reversal of ion-charge selectivity renders the pentameric ligand-gated ion channel GLIC insensitive to anaestheticsA chimeric prokaryotic-eukaryotic pentameric ligand gated ion channel reveals interactions between the extracellular and transmembrane domains shape neurosteroid modulation.Probing residues in the pore-forming (M2) domain of the Cys-loop receptor homologue GLIC reveals some unusual features.Desensitization mechanism in prokaryotic ligand-gated ion channelMapping Two Neurosteroid Modulatory Sites in the Prototypic Pentameric Ligand Gated Ion Channel GLIC.
P2860
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P2860
description
2011 nî lūn-bûn
@nan
2011年の論文
@ja
2011年学术文章
@wuu
2011年学术文章
@zh-cn
2011年学术文章
@zh-hans
2011年学术文章
@zh-my
2011年学术文章
@zh-sg
2011年學術文章
@yue
2011年學術文章
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2011年學術文章
@zh-hant
name
Cys-loop receptor channel blockers also block GLIC.
@en
Cys-loop receptor channel blockers also block GLIC.
@nl
type
label
Cys-loop receptor channel blockers also block GLIC.
@en
Cys-loop receptor channel blockers also block GLIC.
@nl
prefLabel
Cys-loop receptor channel blockers also block GLIC.
@en
Cys-loop receptor channel blockers also block GLIC.
@nl
P2093
P2860
P1433
P1476
Cys-loop receptor channel blockers also block GLIC
@en
P2093
Andrew J Thompson
Hans-Georg Breitinger
Mona Alqazzaz
Sarah C R Lummis
P2860
P304
P356
10.1016/J.BPJ.2011.10.055
P407
P577
2011-12-20T00:00:00Z