Modulation of the oligomerization state of p53 by differential binding of proteins of the S100 family to p53 monomers and tetramers.
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S100A4 interacts with p53 in the nucleus and promotes p53 degradationThe structure of Ca2+-loaded S100A2 at 1.3-Å resolutionMechanistic differences in the transcriptional activation of p53 by 14-3-3 isoformsS100 proteins interact with the N-terminal domain of MDM2In vitro screening and structural characterization of inhibitors of the S100B-p53 interactionInteraction of the p53 DNA-Binding Domain with Its N-Terminal Extension Modulates the Stability of the p53 TetramerCrystal structure of the S100A4-nonmuscle myosin IIA tail fragment complex reveals an asymmetric target binding mechanismp53 Proteoforms and Intrinsic Disorder: An Illustration of the Protein Structure-Function Continuum ConceptSpecific recognition of p53 tetramers by peptides derived from p53 interacting proteinsS100A4 regulates macrophage chemotaxisConservation of DNA-binding specificity and oligomerisation properties within the p53 family.Large-scale proteomic identification of S100 proteins in breast cancer tissues.The calcium-dependent interaction between S100B and the mitochondrial AAA ATPase ATAD3A and the role of this complex in the cytoplasmic processing of ATAD3A.Pathological unfoldomics of uncontrolled chaos: intrinsically disordered proteins and human diseasesThe calcium-binding protein S100B down-regulates p53 and apoptosis in malignant melanoma.Accounting for photophysical processes and specific signal intensity changes in fluorescence-detected sedimentation velocityCancer-associated p53 tetramerization domain mutants: quantitative analysis reveals a low threshold for tumor suppressor inactivationS100A expression in normal corneal-limbal epithelial cells and ocular surface squamous cell carcinoma tissue.Regulation of p53 oligomerization by Ras superfamily protein RBEL1AMolecular dynamic simulation insights into the normal state and restoration of p53 function.Natural products induce a G protein-mediated calcium pathway activating p53 in cancer cells.Ezrin interacts with S100A4 via both its N- and C-terminal domains.p53 sumoylation: mechanistic insights from reconstitution studies.Systems biophysics of gene expression.Ultraslow oligomerization equilibria of p53 and its implications.Biophysical characterizations of human mitochondrial transcription factor A and its binding to tumor suppressor p53.Evaluation of potential interactions between the metastasis-associated protein S100A4 and the tumor suppressor protein p53.Analysis of protein interactions with picomolar binding affinity by fluorescence-detected sedimentation velocity.The tumor suppressor p53: from structures to drug discovery.S100A2 in cancerogenesis: a friend or a foe?The relevance of protein-protein interactions for p53 function: the CPE contribution.S100 proteins as diagnostic and prognostic markers in colorectal and hepatocellular carcinoma.Allosteric modulation of protein oligomerization: an emerging approach to drug design.Control of gene expression by modulated self-assembly.p53 oligomerization status modulates cell fate decisions between growth, arrest and apoptosis.Sedimentation of Reversibly Interacting Macromolecules with Changes in Fluorescence Quantum Yield.RAGE mediates S100A4-induced cell motility via MAPK/ERK and hypoxia signaling and is a prognostic biomarker for human colorectal cancer metastasis.Inhibition of S100A6 induces GVL effects in MLL/AF4-positive ALL in human PBMC-SCID mice.S100A2 promoter-driven conditionally replicative adenovirus targets non-small-cell lung carcinoma.Coexpression and nuclear colocalization of metastasis-promoting protein S100A4 and p53 without mutual regulation in colorectal carcinoma.
P2860
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P2860
Modulation of the oligomerization state of p53 by differential binding of proteins of the S100 family to p53 monomers and tetramers.
description
2009 nî lūn-bûn
@nan
2009年の論文
@ja
2009年論文
@yue
2009年論文
@zh-hant
2009年論文
@zh-hk
2009年論文
@zh-mo
2009年論文
@zh-tw
2009年论文
@wuu
2009年论文
@zh
2009年论文
@zh-cn
name
Modulation of the oligomerizat ...... to p53 monomers and tetramers.
@en
Modulation of the oligomerizat ...... to p53 monomers and tetramers.
@nl
type
label
Modulation of the oligomerizat ...... to p53 monomers and tetramers.
@en
Modulation of the oligomerizat ...... to p53 monomers and tetramers.
@nl
prefLabel
Modulation of the oligomerizat ...... to p53 monomers and tetramers.
@en
Modulation of the oligomerizat ...... to p53 monomers and tetramers.
@nl
P2860
P50
P356
P1476
Modulation of the oligomerizat ...... to p53 monomers and tetramers.
@en
P2093
Jan van Dieck
P2860
P304
13804-13811
P356
10.1074/JBC.M901351200
P407
P577
2009-03-18T00:00:00Z