Overexpression of mutant ataxin-3 in mouse cerebellum induces ataxia and cerebellar neuropathology.
about
RNA interference mitigates motor and neuropathological deficits in a cerebellar mouse model of Machado-Joseph diseaseGene Transfer of Brain-derived Neurotrophic Factor (BDNF) Prevents Neurodegeneration Triggered by FXN DeficiencyRe-establishing ataxin-2 downregulates translation of mutant ataxin-3 and alleviates Machado-Joseph disease.Caffeine alleviates progressive motor deficits in a transgenic mouse model of spinocerebellar ataxia.Calpain inhibition reduces ataxin-3 cleavage alleviating neuropathology and motor impairments in mouse models of Machado-Joseph disease.
P2860
Overexpression of mutant ataxin-3 in mouse cerebellum induces ataxia and cerebellar neuropathology.
description
2013 nî lūn-bûn
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2013年の論文
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2013年学术文章
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2013年学术文章
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2013年学术文章
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name
Overexpression of mutant ataxi ...... and cerebellar neuropathology.
@en
Overexpression of mutant ataxi ...... and cerebellar neuropathology.
@nl
type
label
Overexpression of mutant ataxi ...... and cerebellar neuropathology.
@en
Overexpression of mutant ataxi ...... and cerebellar neuropathology.
@nl
prefLabel
Overexpression of mutant ataxi ...... and cerebellar neuropathology.
@en
Overexpression of mutant ataxi ...... and cerebellar neuropathology.
@nl
P2860
P50
P1433
P1476
Overexpression of mutant ataxi ...... and cerebellar neuropathology.
@en
P2093
Isabel Nascimento-Ferreira
Mariana Conceição
P2860
P2888
P304
P356
10.1007/S12311-012-0432-0
P577
2013-08-01T00:00:00Z
P5875
P6179
1028839288