A small molecule with osteogenesis-inducing activity in multipotent mesenchymal progenitor cells.Purmorphamine activates the Hedgehog pathway by targeting Smoothened.A Smoothened receptor agonist is neuroprotective and promotes regeneration after ischemic brain injuryPurmorphamine increases DARPP-32 differentiation in human striatal neural stem cells through the Hedgehog pathway.Cell attachment and response to photocured, degradable bone adhesives containing tricalcium phosphate and purmorphamine.Virtual ligand-based screening reveals purmorphamine analogs with the capacity to induce the osteogenic differentiation of human mesenchymal stem cells.Hedgehog signaling and osteoblast gene expression are regulated by purmorphamine in human mesenchymal stem cells.The effect of purmorphamine and sirolimus on osteogenic differentiation of human bone marrow-derived mesenchymal stem cells.Purmorphamine and oxysterols accelerate and promote osteogenic differentiation of mesenchymal stem cells in vitro.Purmorphamine enhances osteogenic activity of human osteoblasts derived from bone marrow mesenchymal cells
P921
Q30872831-169D3543-988C-4F22-9955-2DC160EF96D3Q34483948-AF885E8D-41A7-461F-8330-E8FCB2F071C2Q36291166-A0B8B2FD-8421-4817-BA57-B3F918705422Q39587323-D2E2ED37-4209-410C-93CF-9D3592063A95Q42814031-7BB92535-268E-40C2-A2D8-D363C4E2070CQ45348347-1F1061C6-0ECE-4135-9A2A-AE74956C7614Q50610661-D4A24911-A116-4456-A9B7-09AFBD1CE432Q50771131-CF82E673-E12B-4120-AA3F-05E3C3F752EFQ53287130-D19F44F2-EBB7-43FC-9090-7F6F9A13A20CQ81890350-6923EAD3-F0AB-4580-AF6A-3C4A87AADFA7
P921
description
chemesch Verbindung
@lb
chemical compound
@en
chemical compound
@en-ca
chemical compound
@en-gb
chemická sloučenina
@cs
chemická zlúčenina
@sk
chemiese verbinding
@af
chemische Verbindung
@de
chemische Verbindung
@de-ch
chemische verbinding
@nl
name
Purmorfamin
@sh
Purmorfamin
@sr
purmorphamine
@en
type
label
Purmorfamin
@sh
Purmorfamin
@sr
purmorphamine
@en
prefLabel
Purmorfamin
@sh
Purmorfamin
@sr
purmorphamine
@en
P592
P661
P662
P683
P1579
P2067
520.258674
P231
483367-10-8
P233
C1CCC(CC1)N2C=NC3=C2N=C(N=C3NC4=CC=C(C=C4)N5CCOCC5)OC6=CC=CC7=CC=CC=C76
P234
1S/C31H32N6O2/c1-2-9-25(10-3-1 ...... ,1-3,9-10,17-20H2,(H,33,34,35)
P235
FYBHCRQFSFYWPY-UHFFFAOYSA-N
P274
C₃₁H₃₂N₆O₂
P3117
DTXSID20415293
P592
CHEMBL1221984
P652
PB12M2F8KY