about
P688
Self-association of the SET domains of human ALL-1 and of Drosophila TRITHORAX and ASH1 proteinsDivergent hTAFII31-binding motifs hidden in activation domainsProtein interactions of the MLL PHD fingers modulate MLL target gene regulation in human cells.Involvement of a homolog of Drosophila trithorax by 11q23 chromosomal translocations in acute leukemiasHuman RNA polymerase II-association factor 1 (hPaf1/PD2) regulates histone methylation and chromatin remodeling in pancreatic cancerLeukemia proto-oncoprotein MLL forms a SET1-like histone methyltransferase complex with menin to regulate Hox gene expressionHistone methyltransferase MLL1 regulates MDR1 transcription and chemoresistanceSolution structure of the nonmethyl-CpG-binding CXXC domain of the leukaemia-associated MLL histone methyltransferasec-Myb, Menin, GATA-3, and MLL form a dynamic transcription complex that plays a pivotal role in human T helper type 2 cell developmentStructural basis for the requirement of additional factors for MLL1 SET domain activity and recognition of epigenetic marksNew insight into the molecular mechanisms of MLL-associated leukemiaMenin and MLL cooperatively regulate expression of cyclin-dependent kinase inhibitorsOn the mechanism of multiple lysine methylation by the human mixed lineage leukemia protein-1 (MLL1) core complexStructure of the MLL CXXC domain-DNA complex and its functional role in MLL-AF9 leukemia.Bilateral orbital myeloid sarcoma preceding acute myeloid leukemia in an adult: a case report and review of the literatureThe ability of MLL to bind RUNX1 and methylate H3K4 at PU.1 regulatory regions is impaired by MDS/AML-associated RUNX1/AML1 mutations.Biochemical reconstitution and phylogenetic comparison of human SET1 family core complexes involved in histone methylationUnique Role of the WD-40 Repeat Protein 5 (WDR5) Subunit within the Mixed Lineage Leukemia 3 (MLL3) Histone Methyltransferase ComplexDNA Sequence Recognition of Human CXXC Domains and Their Structural Determinants.
P921
Q22011188-2F0F00B1-4319-4A78-8E21-831905E10E3DQ22254120-09FAF4C5-C198-4D8D-8DDD-F77C177FAC90Q24291156-9F2EC59D-3944-4604-8C56-8656DDAD4131Q24294368-7577F0B7-5F6A-4DD0-8E20-C42ED5D90D66Q24295252-8350A24A-DE53-41E4-B280-3CF5FFDCDEC6Q24297027-9A73FC77-FF99-44B3-9BC1-9B7D0F8F9A23Q24300652-5457F08C-D3A7-4CF0-B862-F383AD7A0F24Q24304207-E53777A4-57C9-4FFE-8D5E-6AD15E781EABQ24313643-105CFD6B-1969-406C-9B12-EB3C4BB1A515Q24324784-F3086FA1-E9A1-46D0-B2F1-51E919391E20Q24336625-3069DBA9-A332-4A55-AE8D-6A1C4ECBAEF7Q24337658-2250C4BD-0C9D-46A0-8C89-64B1521BAA04Q24339403-F7E3E43B-0FD6-43E6-B780-BC92DDAC8079Q27658663-9E6ACA94-91CF-4DFA-8497-DBA4D3A33380Q28076710-87A1B80E-A17C-4917-9AA9-A37FC3096AC4Q32884582-49A0975D-6F60-4650-914A-1AAB49FAFC02Q35172965-CA022070-DA5E-4910-8911-23A0CF4810D6Q36283485-58295795-B45F-439C-AB4A-E5788ABF0B7FQ47257048-6CF4BA28-02A8-43B9-9549-7E6638A12C8A
P921
description
Protein in Homo sapiens
@de
mammalian protein found in Homo sapiens
@en
protein
@id
protein
@sv
proteinë
@sq
proteïne in Lysine methyltransferase 2A
@nl
protèin
@ace
protéine
@fr
بروتين في الإنسان العاقل
@ar
name
Lysine methyltransferase 2A
@en
Lysine methyltransferase 2A
@nl
type
label
Lysine methyltransferase 2A
@en
Lysine methyltransferase 2A
@nl
altLabel
ALL-1
@en
CXXC-type zinc finger protein 7
@en
KMT2A
@en
Myeloid/lymphoid or mixed-lineage leukemia protein 1
@en
Myeloid/lymphoid or mixed-lineage leukemia
@en
histone-lysine N-methyltransferase 2A
@en
lysine (K)-specific methyltransferase 2A
@en
lysine N-methyltransferase 2A
@en
mixed lineage leukemia 1
@en
myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila)
@en
prefLabel
Lysine methyltransferase 2A
@en
Lysine methyltransferase 2A
@nl
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D12.776.260.560
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ENSP00000374157
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