Leukemia proto-oncoprotein MLL forms a SET1-like histone methyltransferase complex with menin to regulate Hox gene expression
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Cdx4 and menin co-regulate Hoxa9 expression in hematopoietic cellsGenome-wide analysis of menin binding provides insights into MEN1 tumorigenesis.Regulation of HOXA2 gene expression by the ATP-dependent chromatin remodeling enzyme CHD8Camptothecin-induced downregulation of MLL5 contributes to the activation of tumor suppressor p53A higher-order complex containing AF4 and ENL family proteins with P-TEFb facilitates oncogenic and physiologic MLL-dependent transcriptionIdentification and characterization of the human Set1B histone H3-Lys4 methyltransferase complexWdr82 is a C-terminal domain-binding protein that recruits the Setd1A Histone H3-Lys4 methyltransferase complex to transcription start sites of transcribed human genesA phospho/methyl switch at histone H3 regulates TFIID association with mitotic chromosomes.Menin stimulates homology-directed DNA repairPTIP associates with MLL3- and MLL4-containing histone H3 lysine 4 methyltransferase complexCoactivator as a target gene specificity determinant for histone H3 lysine 4 methyltransferasesBAT3 and SET1A form a complex with CTCFL/BORIS to modulate H3K4 histone dimethylation and gene expressionThe double-histone-acetyltransferase complex ATAC is essential for mammalian developmentc-Myb, Menin, GATA-3, and MLL form a dynamic transcription complex that plays a pivotal role in human T helper type 2 cell developmentThe tumor suppressor Cdc73 functionally associates with CPSF and CstF 3' mRNA processing factorsIdentification of the MLL2 complex as a coactivator for estrogen receptor alphaMenin suppresses osteoblast differentiation by antagonizing the AP-1 factor, JunDMolecular regulation of H3K4 trimethylation by Wdr82, a component of human Set1/COMPASSWDR5 interacts with mixed lineage leukemia (MLL) protein via the histone H3-binding pocketThe deubiquitinating enzyme BAP1 regulates cell growth via interaction with HCF-1.Association of C-terminal ubiquitin hydrolase BRCA1-associated protein 1 with cell cycle regulator host cell factor 1Ronin is essential for embryogenesis and the pluripotency of mouse embryonic stem cellsNew insight into the molecular mechanisms of MLL-associated leukemiaKnockdown of ALR (MLL2) reveals ALR target genes and leads to alterations in cell adhesion and growth.Menin and MLL cooperatively regulate expression of cyclin-dependent kinase inhibitorsGlobal and Hox-specific roles for the MLL1 methyltransferaseA human protein complex homologous to the Drosophila MSL complex is responsible for the majority of histone H4 acetylation at lysine 16The tumor suppressor menin regulates hematopoiesis and myeloid transformation by influencing Hox gene expression.Host cell factor and an uncharacterized SANT domain protein are stable components of ATAC, a novel dAda2A/dGcn5-containing histone acetyltransferase complex in DrosophilaThe parafibromin tumor suppressor protein is part of a human Paf1 complexAn emerging model for BAP1's role in regulating cell cycle progressionThe Trithorax group protein Ash2l and Saf-A are recruited to the inactive X chromosome at the onset of stable X inactivationThe ubiquitin carboxyl hydrolase BAP1 forms a ternary complex with YY1 and HCF-1 and is a critical regulator of gene expressionE2F1 mediates DNA damage and apoptosis through HCF-1 and the MLL family of histone methyltransferasesRegulation of mir-196b by MLL and its overexpression by MLL fusions contributes to immortalizationOverexpression of transcripts originating from the MMSET locus characterizes all t(4;14)(p16;q32)-positive multiple myeloma patientsTranscription of bxd noncoding RNAs promoted by trithorax represses Ubx in cis by transcriptional interferenceNatural history of S-adenosylmethionine-binding proteinsSystematic Classification of Mixed-Lineage Leukemia Fusion Partners Predicts Additional Cancer PathwaysHistone methyltransferases: novel targets for tumor and developmental defects
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P2860
Leukemia proto-oncoprotein MLL forms a SET1-like histone methyltransferase complex with menin to regulate Hox gene expression
description
2004 nî lūn-bûn
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2004 թուականի Յուլիսին հրատարակուած գիտական յօդուած
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2004 թվականի հուլիսին հրատարակված գիտական հոդված
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2004年の論文
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2004年論文
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2004年論文
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2004年論文
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2004年論文
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2004年論文
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2004年论文
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Leukemia proto-oncoprotein MLL ...... o regulate Hox gene expression
@ast
Leukemia proto-oncoprotein MLL ...... o regulate Hox gene expression
@en
Leukemia proto-oncoprotein MLL ...... o regulate Hox gene expression
@en-gb
Leukemia proto-oncoprotein MLL ...... o regulate Hox gene expression
@nl
type
label
Leukemia proto-oncoprotein MLL ...... o regulate Hox gene expression
@ast
Leukemia proto-oncoprotein MLL ...... o regulate Hox gene expression
@en
Leukemia proto-oncoprotein MLL ...... o regulate Hox gene expression
@en-gb
Leukemia proto-oncoprotein MLL ...... o regulate Hox gene expression
@nl
prefLabel
Leukemia proto-oncoprotein MLL ...... o regulate Hox gene expression
@ast
Leukemia proto-oncoprotein MLL ...... o regulate Hox gene expression
@en
Leukemia proto-oncoprotein MLL ...... o regulate Hox gene expression
@en-gb
Leukemia proto-oncoprotein MLL ...... o regulate Hox gene expression
@nl
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P2860
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P1476
Leukemia proto-oncoprotein MLL ...... o regulate Hox gene expression
@en
P2093
Akihiko Yokoyama
Deborah J Aufiero
Issay Kitabayashi
Joanna Wysocka
Michael L Cleary
Zhong Wang
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P304
P3181
P356
10.1128/MCB.24.13.5639-5649.2004
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P577
2004-07-01T00:00:00Z