about
P688
A Tumor suppressor complex with GAP activity for the Rag GTPases that signal amino acid sufficiency to mTORC1Sestrins inhibit mTORC1 kinase activation through the GATOR complexKICSTOR recruits GATOR1 to the lysosome and is necessary for nutrients to regulate mTORC1KLHL22 activates amino-acid-dependent mTORC1 signalling to promote tumorigenesis and ageing
P921
description
Protein in Homo sapiens
@de
mammalian protein found in Homo sapiens
@en
protein
@id
protein
@sv
proteinë
@sq
proteïne in DEP domain containing 5
@nl
protèin
@ace
protéine
@fr
بروتين في الإنسان العاقل
@ar
name
DEP domain containing 5, GATOR1 subcomplex subunit
@en
type
label
DEP domain containing 5, GATOR1 subcomplex subunit
@en
altLabel
DEP domain containing 5
@en
DEP domain-containing protein 5
@en
DEPDC5
@en
GATOR complex protein DEPDC5
@en
prefLabel
DEP domain containing 5, GATOR1 subcomplex subunit
@en
P361
P637
P680
P681
P682
P705
P352
P637
P31
P352
P361
P527
P637
NP_001007189
NP_001129501
NP_001229825
NP_001229826
NP_001350781
NP_001350783
NP_001351247
NP_001351248
NP_001351249
NP_001356830
P681
P682
P702
P703
P705
ENSP00000371545
ENSP00000371546
ENSP00000383101
ENSP00000383105
ENSP00000383107
ENSP00000383108
ENSP00000402173
ENSP00000405351
ENSP00000410544
ENSP00000412057