about
A novel function for SMN, the spinal muscular atrophy disease gene product, in pre-mRNA splicingSpinal muscular atrophy disrupts the interaction of ZPR1 with the SMN proteinRpp20 interacts with SMN and is re-distributed into SMN granules in response to stressDeficiency of the zinc finger protein ZPR1 causes defects in transcription and cell cycle progressionThe spinal muscular atrophy disease gene product, SMN, and its associated protein SIP1 are in a complex with spliceosomal snRNP proteinsThe SMN interactome includes Myb-binding protein 1aA novel nuclear structure containing the survival of motor neurons proteinThe survival motor neuron protein forms soluble glycine zipper oligomersSMN and symmetric arginine dimethylation of RNA polymerase II C-terminal domain control terminationGemin5 delivers snRNA precursors to the SMN complex for snRNP biogenesisIn vitro and in cellulo evidences for association of the survival of motor neuron complex with the fragile X mental retardation proteinLuTHy: a double-readout bioluminescence-based two-hybrid technology for quantitative mapping of protein-protein interactions in mammalian cells
P921
Q22008514-2347D375-9F07-4313-87CD-8A5CD412E2A3Q24291073-1C049D3B-8DB3-4C11-B163-72E9D74B7CB2Q24304268-00708D6C-5AB1-4730-8B19-F1E63BBABD64Q24309626-F9366D4E-E936-40FE-908E-069E734F257FQ24316085-A219499C-E507-4CFA-8CB8-00A0F8A10CFBQ24318856-7288BF02-7683-48C3-B976-FC823B1313C2Q24324247-EBAE4851-20C9-4478-9346-111776D71EABQ24600623-323F4F25-7408-4141-91C3-184B9E2E7C26Q28115292-E189E004-C957-40B5-90A3-088758034FAFQ28115894-3E030D52-6C98-44B0-8799-DF47DE85355FQ28116617-A756881F-A324-494D-BB76-41D8097DF9FAQ56967338-4E73A121-3F62-4081-9B8B-BFF11EF49DE1
P921
description
humanes Protein
@de
mammalian protein found in Homo sapiens
@en
menselijk eiwit
@nl
protein
@id
proteinë
@sq
protèin
@ace
protéine humaine
@fr
بروتين بشري
@ar
name
Survival of motor neuron 2, centromeric
@en
Survival of motor neuron 2, centromeric
@nl
type
label
Survival of motor neuron 2, centromeric
@en
Survival of motor neuron 2, centromeric
@nl
altLabel
SMN1
@en
SMN2
@en
component of gems 1
@en
gemin-1
@en
survival motor neuron protein
@en
survival of motor neuron 2 isoform D2A2B345
@en
survival of motor neuron 2 isoform D2A2B3457
@en
survival of motor neuron 2 isoform D2A3457
@en
survival of motor neuron 2 isoform D2B3457
@en
survival of motor neuron 2 isoform D345
@en
prefLabel
Survival of motor neuron 2, centromeric
@en
Survival of motor neuron 2, centromeric
@nl
P637
P638
P680
P681
P682
P705
P352
P486
P637
P31
P352
P486
P637
NP_001284644
XP_011541898
XP_011541899
XP_011541900
P638
P681
P682
P703
P705
ENSP00000305857
ENSP00000370083
ENSP00000370117
ENSP00000370118
ENSP00000370119
ENSP00000422679
ENSP00000423298
ENSP00000424282
ENSP00000424799
ENSP00000424926