Galactic cosmic radiation leads to cognitive impairment and increased aβ plaque accumulation in a mouse model of Alzheimer's disease
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Evaluating biomarkers to model cancer risk post cosmic ray exposureIrradiation of Neurons with High-Energy Charged Particles: An In Silico Modeling ApproachMicroglia of prefrontal white matter in suicide(56)Fe Particle Exposure Results in a Long-Lasting Increase in a Cellular Index of Genomic Instability and Transiently Suppresses Adult Hippocampal Neurogenesis in Vivo.The effect of spaceflight on mouse olfactory bulb volume, neurogenesis, and cell death indicates the protective effect of novel environment.Biological Effects of Space Radiation and Development of Effective Countermeasures.Emerging issues in radiogenic cataracts and cardiovascular diseaseSynergistic effect of high charge and energy particle radiation and chronological age on biomarkers of oxidative stress and tissue degeneration: a ground-based study using the vertebrate laboratory model organism Oryzias latipes.Is a hypothetical melanoma-like neuromelanin the underlying factor essential for the aetiopathogenesis and clinical manifestations of multiple sclerosis?How safe is safe enough? Radiation risk for a human mission to MarsStudy protocol to examine the effects of spaceflight and a spaceflight analog on neurocognitive performance: extent, longevity, and neural bases.Combined Exposure to Simulated Microgravity and Acute or Chronic Radiation Reduces Neuronal Network Integrity and Survival.Long-term Autophagy and Nrf2 Signaling in the Hippocampi of Developing Mice after Carbon Ion Exposure.Total body 100-mGy X-irradiation does not induce Alzheimer's disease-like pathogenesis or memory impairment in miceThermal injury lowers the threshold for radiation-induced neuroinflammation and cognitive dysfunction.Acute and fractionated exposure to high-LET (56)Fe HZE-particle radiation both result in similar long-term deficits in adult hippocampal neurogenesis.Chronic low-dose-rate ionising radiation affects the hippocampal phosphoproteome in the ApoE-/- Alzheimer's mouse model.Etiology and pathogenesis of late-onset Alzheimer's disease.Interplanetary regenerative medicine for mission Mars of SpaceX and NASA.Individual variations in dose response for spatial memory learning among outbred wistar rats exposed from 5 to 20 cGy of (56) Fe particles.Neurogenic Effects of Low-Dose Whole-Body HZE (Fe) Ion and Gamma Irradiation.Examining the Effects of External or Internal Radiation Exposure of Juvenile Mice on Late Morbidity after Infection with Influenza A.Low-dose proton radiation effects in a transgenic mouse model of Alzheimer's disease - Implications for space travel.A pilot study of neuropsychological functions, APOE and amyloid imaging in patients with gliomas.Metabolic Pathways of the Warburg Effect in Health and Disease: Perspectives of Choice, Chain or Chance.Low-dose total-body carbon-ion irradiations induce early transcriptional alteration without late Alzheimer's disease-like pathogenesis and memory impairment in mice.Ionizing radiation causes increased tau phosphorylation in primary neurons.Space-brain: The negative effects of space exposure on the central nervous system.Repair kinetics of DNA double-strand breaks and incidence of apoptosis in mouse neural stem/progenitor cells and their differentiated neurons exposed to ionizing radiation.Protection against neurodegenerative disease on Earth and in space.Long-term effects of simulated microgravity and/or chronic exposure to low-dose gamma radiation on behavior and blood-brain barrier integrity.Limitations in predicting the space radiation health risk for exploration astronauts.Role of Ionizing Radiation in Neurodegenerative Diseases.Temporary microglia-depletion after cosmic radiation modifies phagocytic activity and prevents cognitive deficits.
P2860
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P2860
Galactic cosmic radiation leads to cognitive impairment and increased aβ plaque accumulation in a mouse model of Alzheimer's disease
description
2012 nî lūn-bûn
@nan
2012 թուականին հրատարակուած գիտական յօդուած
@hyw
2012 թվականին հրատարակված գիտական հոդված
@hy
2012年の論文
@ja
2012年論文
@yue
2012年論文
@zh-hant
2012年論文
@zh-hk
2012年論文
@zh-mo
2012年論文
@zh-tw
2012年论文
@wuu
name
Galactic cosmic radiation lead ...... e model of Alzheimer's disease
@ast
Galactic cosmic radiation lead ...... e model of Alzheimer's disease
@en
Galactic cosmic radiation lead ...... e model of Alzheimer's disease
@en-gb
Galactic cosmic radiation lead ...... e model of Alzheimer's disease
@nl
type
label
Galactic cosmic radiation lead ...... e model of Alzheimer's disease
@ast
Galactic cosmic radiation lead ...... e model of Alzheimer's disease
@en
Galactic cosmic radiation lead ...... e model of Alzheimer's disease
@en-gb
Galactic cosmic radiation lead ...... e model of Alzheimer's disease
@nl
altLabel
Galactic Cosmic Radiation Lead ...... e Model of Alzheimer’s Disease
@en
prefLabel
Galactic cosmic radiation lead ...... e model of Alzheimer's disease
@ast
Galactic cosmic radiation lead ...... e model of Alzheimer's disease
@en
Galactic cosmic radiation lead ...... e model of Alzheimer's disease
@en-gb
Galactic cosmic radiation lead ...... e model of Alzheimer's disease
@nl
P2093
P2860
P3181
P1433
P1476
Galactic cosmic radiation lead ...... e model of Alzheimer's disease
@en
P2093
Cynthia A Lemere
Jacqueline P Williams
Jeffrey L Frost
John A Olschowka
Jonathan D Cherry
P2860
P304
P3181
P356
10.1371/JOURNAL.PONE.0053275
P407
P50
P577
2012-12-31T00:00:00Z