Different quaternary structures of human RECQ1 are associated with its dual enzymatic activity - Wikidata - wikimedia - TriplyDB

Different quaternary structures of human RECQ1 are associated with its dual enzymatic activity

Different quaternary structures of human RECQ1 are associated with its dual enzymatic activity

http://www.wikidata.org/entity/Q21145897

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Unwinding and rewinding: double faces of helicase?Dual DNA unwinding activities of the Rothmund-Thomson syndrome protein, RECQ4 The RecQ DNA helicases in DNA repair RecQ helicase translocates along single-stranded DNA with a moderate processivity and tight mechanochemical coupling Human premature aging, DNA repair and RecQ helicases Crystal structure of Rsr, an ortholog of the antigenic Ro protein, links conformational flexibility to RNA binding activity Structure of the human RECQ1 helicase reveals a putative strand-separation pin An essential DNA strand-exchange activity is conserved in the divergent N-termini of BLM orthologs.A helical bundle in the N-terminal domain of the BLM helicase mediates dimer and potentially hexamer formation.Human RECQ1 is a DNA damage responsive protein required for genotoxic stress resistance and suppression of sister chromatid exchanges.Human RECQL1 participates in telomere maintenance Distinct roles of RECQ1 in the maintenance of genomic stability.Human RECQ1 interacts with Ku70/80 and modulates DNA end-joining of double-strand breaks Human RECQ1 helicase-driven DNA unwinding, annealing, and branch migration: insights from DNA complex structures RECQ1 interacts with FEN-1 and promotes binding of FEN-1 to telomeric chromatin.Catalytic strand separation by RECQ1 is required for RPA-mediated response to replication stress.Polarity and bypass of DNA heterology during branch migration of Holliday junctions by human RAD54, BLM, and RECQ1 proteins Human RecQ helicases in DNA repair, recombination, and replication.Intrinsic ssDNA annealing activity in the C-terminal region of WRN.Multimeric BLM is dissociated upon ATP hydrolysis and functions as monomers in resolving DNA structures Enhancement of human DNA polymerase η activity and fidelity is dependent upon a bipartite interaction with the Werner syndrome protein RECQ1 is required for cellular resistance to replication stress and catalyzes strand exchange on stalled replication fork structures.Unique and important consequences of RECQ1 deficiency in mammalian cells.RECQ1 possesses DNA branch migration activity.RECQL: a new breast cancer susceptibility gene.Rising from the RecQ-age: the role of human RecQ helicases in genome maintenance The BLM dissolvasome in DNA replication and repair.Visualization of human Bloom's syndrome helicase molecules bound to homologous recombination intermediates.Single nucleotide polymorphism in RECQL and survival in resectable pancreatic adenocarcinoma.Human RECQ1 promotes restart of replication forks reversed by DNA topoisomerase I inhibition.RecQ helicases: multiple structures for multiple functions?Rad54, the motor of homologous recombination.Probing Genome Maintenance Functions of human RECQ1.Non-B DNA Secondary Structures and Their Resolution by RecQ Helicases.Rad51 protein stimulates the branch migration activity of Rad54 protein.Complex activities of the human Bloom's syndrome helicase are encoded in a core region comprising the RecA and Zn-binding domains.Multimerization domains are associated with apparent strand exchange activity in BLM and WRN DNA helicases.A prominent β-hairpin structure in the winged-helix domain of RECQ1 is required for DNA unwinding and oligomer formation.Site-directed mutants of human RECQ1 reveal functional importance of the zinc binding domain The Werner syndrome protein binds replication fork and holliday junction DNAs as an oligomer.

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Different quaternary structures of human RECQ1 are associated with its dual enzymatic activity

http://www.wikidata.org/entity/Q21145897

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2007 nî lūn-bûn

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2007 թուականի Փետրուարին հրատարակուած գիտական յօդուած

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2007 թվականի փետրվարին հրատարակված գիտական հոդված

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2007年の論文

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2007年論文

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2007年論文

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2007年論文

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2007年論文

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2007年論文

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2007年论文

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Different quaternary structure ...... th its dual enzymatic activity

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Different quaternary structure ...... th its dual enzymatic activity

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Different quaternary structure ...... th its dual enzymatic activity

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Different quaternary structure ...... th its dual enzymatic activity

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Different quaternary structure ...... th its dual enzymatic activity

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Different quaternary structure ...... th its dual enzymatic activity

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Different quaternary structure ...... th its dual enzymatic activity

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Different quaternary structure ...... th its dual enzymatic activity

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Different Quaternary Structure ...... th Its Dual Enzymatic Activity

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Different quaternary structure ...... th its dual enzymatic activity

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Different quaternary structure ...... th its dual enzymatic activity

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Different quaternary structure ...... th its dual enzymatic activity

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JOURNAL.PBIO.0050020

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Different quaternary structure ...... th its dual enzymatic activity

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Alessandro Vindigni

http://www.w3.org/2001/XMLSchema#string

Benedetta Niccolini

http://www.w3.org/2001/XMLSchema#string

Fabienne Beuron

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Laura Muzzolini

http://www.w3.org/2001/XMLSchema#string

Mathieu Rappas

http://www.w3.org/2001/XMLSchema#string

Venkateswarlu Popuri

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P2860

Oligomeric ring structure of the Bloom's syndrome helicase

Characterization of the human and mouse WRN 3'-->5' exonuclease

The Bloom's and Werner's syndrome proteins are DNA structure-specific helicases

Helicase structure and mechanism

RECQ1 helicase interacts with human mismatch repair factors that regulate genetic recombination

Characterization and mutational analysis of the RecQ core of the bloom syndrome protein

The Bloom's syndrome gene product is homologous to RecQ helicases

Structure of the single-strand annealing domain of human RAD52 protein

Human RECQ5beta, a protein with DNA helicase and strand-annealing activities in a single polypeptide

Analysis of the unwinding activity of the dimeric RECQ1 helicase in the presence of human replication protein A

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e20

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scholarly article

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10.1371/JOURNAL.PBIO.0050020

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2

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5

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Ardan Patwardhan

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2007-02-01T00:00:00Z

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6575583

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17227144

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1769423

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