BRICHOS - a superfamily of multidomain proteins with diverse functions
about
High-resolution structure of a BRICHOS domain and its implications for anti-amyloid chaperone activity on lung surfactant protein C.Itm2a, a target gene of GATA-3, plays a minimal role in regulating the development and function of T cellsThe endochondral bone protein CHM1 sustains an undifferentiated, invasive phenotype, promoting lung metastasis in Ewing sarcoma.Specific chaperones and regulatory domains in control of amyloid formation.Gastrokines: stomach-specific proteins with putative homeostatic and tumor suppressor roles.The chaperone domain BRICHOS prevents CNS toxicity of amyloid-β peptide in Drosophila melanogasterSubdivision of the MDR superfamily of medium-chain dehydrogenases/reductases through iterative hidden Markov model refinementItm2a expression in the developing mouse first lower molar, and the subcellular localization of Itm2a in mouse dental epithelial cellsTenomodulin expression in the periodontal ligament enhances cellular adhesion.The role of gastrokine 1 in gastric cancer.Network analysis of circular permutations in multidomain proteins reveals functional linkages for uncharacterized proteins.The Familial British Dementia Mutation Promotes Formation of Neurotoxic Cystine Cross-linked Amyloid Bri (ABri) OligomersLost after translation: insights from pulmonary surfactant for understanding the role of alveolar epithelial dysfunction and cellular quality control in fibrotic lung disease.Lessons from a Rare Familial Dementia: Amyloid and Beyond.A molecular chaperone breaks the catalytic cycle that generates toxic Aβ oligomersLoss of gastrokine-2 drives premalignant gastric inflammation and tumor progression.BRICHOS domain associated with lung fibrosis, dementia and cancer--a chaperone that prevents amyloid fibril formation?Control of amyloid assembly by autoregulation.Gastrokine-2 suppresses epithelial mesenchymal transition through PI3K/AKT/GSK3β signaling in gastric cancer.Current and future treatment of amyloid diseases.Trophoblast expression dynamics of the tumor suppressor gene gastrokine 2.Transthyretin and BRICHOS: The Paradox of Amyloidogenic Proteins with Anti-Amyloidogenic Activity for Aβ in the Central Nervous System.Structural characterization and biological properties of human gastrokine 1.Antagonistic evolution of an antibiotic and its molecular chaperone: how to maintain a vital ectosymbiosis in a highly fluctuating habitat.Folding and Intramembraneous BRICHOS Binding of the Prosurfactant Protein C Transmembrane SegmentBRICHOS domains efficiently delay fibrillation of amyloid β-peptide.Transient structure and dynamics in the disordered c-Myc transactivation domain affect Bin1 binding.Itm2a silencing rescues lamin A mediated inhibition of 3T3-L1 adipocyte differentiation.Differential expression and cellular localization of novel isoforms of the tendon biomarker tenomodulin.Bri2 BRICHOS client specificity and chaperone activity are governed by assembly state.BRICHOS domain of Bri2 inhibits islet amyloid polypeptide (IAPP) fibril formation and toxicity in human beta cells.Caenorhabditis elegans BRICHOS Domain-Containing Protein C09F5.1 Maintains Thermotolerance and Decreases Cytotoxicity of Aβ42 by Activating the UPR.
P2860
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P2860
BRICHOS - a superfamily of multidomain proteins with diverse functions
description
2009 nî lūn-bûn
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2009 թուականին հրատարակուած գիտական յօդուած
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2009 թվականին հրատարակված գիտական հոդված
@hy
2009年の論文
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2009年論文
@yue
2009年論文
@zh-hant
2009年論文
@zh-hk
2009年論文
@zh-mo
2009年論文
@zh-tw
2009年论文
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name
BRICHOS - a superfamily of multidomain proteins with diverse functions
@ast
BRICHOS - a superfamily of multidomain proteins with diverse functions
@en
BRICHOS - a superfamily of multidomain proteins with diverse functions
@en-gb
BRICHOS - a superfamily of multidomain proteins with diverse functions
@nl
type
label
BRICHOS - a superfamily of multidomain proteins with diverse functions
@ast
BRICHOS - a superfamily of multidomain proteins with diverse functions
@en
BRICHOS - a superfamily of multidomain proteins with diverse functions
@en-gb
BRICHOS - a superfamily of multidomain proteins with diverse functions
@nl
prefLabel
BRICHOS - a superfamily of multidomain proteins with diverse functions
@ast
BRICHOS - a superfamily of multidomain proteins with diverse functions
@en
BRICHOS - a superfamily of multidomain proteins with diverse functions
@en-gb
BRICHOS - a superfamily of multidomain proteins with diverse functions
@nl
P2860
P356
P1433
P1476
BRICHOS - a superfamily of multidomain proteins with diverse functions
@en
P2093
Joel Hedlund
P2860
P2888
P356
10.1186/1756-0500-2-180
P407
P577
2009-01-01T00:00:00Z
P5875
P6179
1042225378