Progranulin in frontotemporal lobar degeneration and neuroinflammation - Wikidata - wikimedia - TriplyDB

Progranulin in frontotemporal lobar degeneration and neuroinflammation

Progranulin in frontotemporal lobar degeneration and neuroinflammation

http://www.wikidata.org/entity/Q21245242

about

Alzheimer's disease as homeostatic responses to age-related myelin breakdown The miR-15/107 group of microRNA genes: evolutionary biology, cellular functions, and roles in human diseases The genetics and neuropathology of frontotemporal lobar degeneration Potential mechanisms of progranulin-deficient FTLD Therapeutic and diagnostic challenges for frontotemporal dementia Potential roles of microglial cell progranulin in HIV-associated CNS pathologies and neurocognitive impairment Functional Pattern of Increasing Concentrations of Brain-Derived Neurotrophic Factor in Spiral Ganglion: Implications for Research on Cochlear Implants.The spectrum of mutations in progranulin: a collaborative study screening 545 cases of neurodegeneration Early microgliosis precedes neuronal loss and behavioural impairment in mice with a frontotemporal dementia-causing CHMP2B mutation Progranulin gene variability and plasma levels in bipolar disorder and schizophrenia.Exaggerated inflammation, impaired host defense, and neuropathology in progranulin-deficient mice Evidence of the innate antiviral and neuroprotective properties of progranulin.Progranulin is neurotrophic in vivo and protects against a mutant TDP-43 induced axonopathy Rs5848 variant influences GRN mRNA levels in brain and peripheral mononuclear cells in patients with Alzheimer's disease.TMEM106B expression is reduced in Alzheimer's disease brains Common variant in GRN is a genetic risk factor for hippocampal sclerosis in the elderly.Impaired prosaposin lysosomal trafficking in frontotemporal lobar degeneration due to progranulin mutations Suberoylanilide hydroxamic acid (vorinostat) up-regulates progranulin transcription: rational therapeutic approach to frontotemporal dementia.Cerebrospinal fluid progranulin levels in patients with different multiple sclerosis subtypes.Accelerated lipofuscinosis and ubiquitination in granulin knockout mice suggest a role for progranulin in successful aging.miR-107 regulates granulin/progranulin with implications for traumatic brain injury and neurodegenerative disease Frontotemporal lobar degeneration: epidemiology, pathophysiology, diagnosis and management.Regulation of progranulin expression in human microglia and proteolysis of progranulin by matrix metalloproteinase-12 (MMP-12).Behavioral deficits and progressive neuropathology in progranulin-deficient mice: a mouse model of frontotemporal dementia Association between GRN rs5848 polymorphism and Parkinson's disease in Taiwanese population Genetics of frontotemporal lobar degeneration Progranulin is a chemoattractant for microglia and stimulates their endocytic activity.rs5848 polymorphism and serum progranulin level Progranulin expression is upregulated after spinal contusion in mice.Progranulin and a five transmembrane domain-containing receptor-like gene are the key components in receptor activator of nuclear factor κB (RANK)-dependent formation of multinucleated osteoclasts Loss of function mutations in the progranulin gene are related to pro-inflammatory cytokine dysregulation in frontotemporal lobar degeneration patients.The TMEM106B locus and TDP-43 pathology in older persons without FTLD Progranulin gene delivery protects dopaminergic neurons in a mouse model of Parkinson's disease.A network of RNA and protein interactions in Fronto Temporal Dementia.Low plasma progranulin levels in children with autism.Delayed inflammatory mRNA and protein expression after spinal cord injury.Plasma levels of progranulin and interleukin-6 in frontotemporal lobar degeneration.Prosaposin facilitates sortilin-independent lysosomal trafficking of progranulin.Progranulin deficiency promotes neuroinflammation and neuron loss following toxin-induced injury.Progranulin regulates neuronal outgrowth independent of sortilin

P2860

Q22251261-A0F39CED-327D-4531-B6C9-150CBBF61F18 Q24608620-984C782C-A0A6-4E8D-89D5-0B6C62BA2C22 Q24615201-6723A3CB-892E-40E5-821B-B0CF26AB5E76 Q26863702-565F05D7-0E4D-4441-B05A-B562C6D146DA Q26998919-FFD56386-680B-484A-A9F9-642826EC2650 Q27011876-4D628028-3AD5-4F8A-8CFE-95F9B5AE3019 Q30356318-770A5A37-A62C-458B-85CD-358B3AA39099 Q30495415-7911FE90-D85D-4E27-A4F9-B9669EA076CD Q30847257-2A54BF0B-2A05-4DB1-9694-C7089CF416CA Q31055209-B52129BF-1E85-4146-A48E-658E2F887DBF Q33615151-4423DA92-EAED-4301-8954-9CABD4009824 Q33690042-B0C83F44-E058-4198-85DD-7C8B6719185E Q33725391-67F5F3C0-0951-4634-A07D-07006B8B3B83 Q33742148-29E82B92-9D7E-44C2-A704-DC179CE03DD6 Q33746240-0A91E342-B204-4D90-B6B9-6DE682440F0B Q33808785-127B24BC-F6A5-4386-BFBF-F8EB7BFA9F18 Q33815765-A69150E6-A0A9-4F14-B899-DA8F3A746334 Q33859252-45DA6878-DA09-4914-95AB-B5C645A68C7A Q33946311-533D85AA-AC3A-44A0-8689-0DD29F8F0172 Q33947272-F90F4B95-2A24-42E9-AFCF-1DE7655AD6E3 Q33947283-821D4FAB-5517-4E14-BE71-042C76AB698A Q34046590-D316880D-FF38-4E6B-BE8C-D1288FF5D737 Q34235574-21FBB06A-E20B-47B5-8603-41DB9492CB76 Q34352771-943BC383-63C1-455F-978A-0F8FE80B9B32 Q34559477-6ABE3492-BFEF-4531-BCE9-79266B65C79A Q34574931-831AA04A-BA70-4E40-B816-E249CEC81FD6 Q34760814-D12A6259-AB46-444C-AED3-B5FCCBD67C1A Q34891810-FEAC12C3-FF1F-4396-B677-FF830A19663C Q34916082-0692DB6F-FF5E-40DE-94EA-A779D58FECF3 Q35002815-6A7BE304-ACBC-44B6-94E7-EC1FE06B2056 Q35121652-45196FA8-DCC1-4BA0-A1C6-3890B34F3850 Q35153681-EE3D9FA0-FF40-41DB-B292-46E528249EB5 Q35164339-2ECB5C64-5093-486D-A8C3-7CCBA7E864B8 Q35194634-ED067E3E-5926-4D6E-930F-5EF9E4CA66A7 Q35240854-709080D7-7341-4F50-AF16-BCD4D98434D6 Q35416093-E082A23F-2FCA-4055-834E-B1A2507EA85C Q35859333-2743CED6-B660-4C2F-971C-9267CF83E629 Q36078240-1734CF90-4AF9-45D2-B207-CD94C736BE13 Q36357853-D1DD865E-EE95-43DE-82CE-5950CB7F93D4 Q36430434-1603FA3B-5E27-4FFA-88DD-AEE28ADCD8ED

P2860

Progranulin in frontotemporal lobar degeneration and neuroinflammation

http://www.wikidata.org/entity/Q21245242

description

2007 nî lūn-bûn

@nan

2007 թուականի Փետրուարին հրատարակուած գիտական յօդուած

@hyw

2007 թվականի փետրվարին հրատարակված գիտական հոդված

@hy

2007年の論文

@ja

2007年論文

@yue

2007年論文

@zh-hant

2007年論文

@zh-hk

2007年論文

@zh-mo

2007年論文

@zh-tw

2007年论文

@wuu

name

Progranulin in frontotemporal lobar degeneration and neuroinflammation

@ast

Progranulin in frontotemporal lobar degeneration and neuroinflammation

@en

Progranulin in frontotemporal lobar degeneration and neuroinflammation

@en-gb

Progranulin in frontotemporal lobar degeneration and neuroinflammation

@nl

type

label

Progranulin in frontotemporal lobar degeneration and neuroinflammation

@ast

Progranulin in frontotemporal lobar degeneration and neuroinflammation

@en

Progranulin in frontotemporal lobar degeneration and neuroinflammation

@en-gb

Progranulin in frontotemporal lobar degeneration and neuroinflammation

@nl

prefLabel

Progranulin in frontotemporal lobar degeneration and neuroinflammation

@ast

Progranulin in frontotemporal lobar degeneration and neuroinflammation

@en

Progranulin in frontotemporal lobar degeneration and neuroinflammation

@en-gb

Progranulin in frontotemporal lobar degeneration and neuroinflammation

@nl

P1433

Q21245242-300C10CD-86B5-4608-B245-B2809F5CF161

P1476

Q21245242-D94B22D5-6DAA-471E-BBBD-8C28CD7763BC

P2093

Q21245242-9D75463E-3CB2-433C-9879-2D8BFC3054AD

Q21245242-B3A17BE9-3487-4DEE-9B0F-0C49F2138634

Q21245242-DEA8ECA0-5EB7-45ED-816E-7FE869A68A93

P275

Q21245242-55C91C6E-5EBA-4529-BBE8-F456BE818906

P2860

Q21245242-0127AC62-10D5-4A34-B5C6-A5BCE340A59C

Q21245242-0315134A-E350-4416-8680-FFA33FF2FC75

Q21245242-03F90430-2D1D-4FAB-AAC9-550416A4C3D0

Q21245242-04AF45C1-48CE-44F2-9725-508974C73416

Q21245242-04E551C0-6CB2-41B8-8FF8-D5555678EAC9

Q21245242-0B683AB1-2100-4EF5-AB44-219367B14501

Q21245242-0B9DAC28-890F-4840-8050-310AF3C2319D

Q21245242-0BDD5690-8E22-4489-B380-790C280B76C0

Q21245242-0D54C985-664D-4BEC-97E0-FBDD42BC475D

Q21245242-10776F00-E64B-4CE5-B5CA-AAB5434F9495

P2888

Q21245242-E583094F-76B9-437A-8D9C-9AD748908CE2

P304

Q21245242-5B0CBAB5-42F1-452C-9EF0-1AD0EE9B7A9A

P31

Q21245242-067D1244-0C73-404D-A2D9-2F03BF571553

Q21245242-682E906D-9F70-4580-943A-F5A27BFE383D

P356

Q21245242-3D089816-B1E9-4C35-90EE-0D1018559D97

P407

Q21245242-7DD8BE69-D8BD-406C-BC2F-4696B905585E

P433

Q21245242-BF320992-7439-4083-A75B-E3505C6CCF25

P478

Q21245242-A425B66B-6F5B-4819-8CE9-B8B2F8B35C99

P50

Q21245242-5DEFE23B-1E66-429D-89AD-18BDF84C8AD5

P5008

Q21245242-62CE3F91-9079-4D0B-BCF7-0E46B4EC8E53

P577

Q21245242-11E3A6E2-5DB0-4728-952A-25B987F08059

P5875

Q21245242-2FC3F816-84CC-424C-901B-C9FCF1FB628E

P6179

Q21245242-56E83778-A9C6-4995-ACD0-784632B34480

P698

Q21245242-02ACCEE3-F283-44B7-B949-7E22E14E99B3

P921

Q21245242-10B09281-6FEA-4C85-8818-B7CC0DEB7510

Q21245242-4D9B0E91-8E06-4ADC-912A-787E6EEB006E

Q21245242-9f2e51a3-bf16-4b96-a6cb-ae60ae46ca1a

Q21245242-C898B6B3-A04B-4B84-887C-B70089F059B1

P932

Q21245242-31C3BB32-8176-47BC-9E91-CF3555E50198

P356

P1433

Journal of Neuroinflammation

P1476

Progranulin in frontotemporal lobar degeneration and neuroinflammation

@en

P2093

Ian R A Mackenzie

http://www.w3.org/2001/XMLSchema#string

Michael L Hutton

http://www.w3.org/2001/XMLSchema#string

Zeshan Ahmed

http://www.w3.org/2001/XMLSchema#string

P275

Creative Commons Attribution 2.0 Generic

P2860

Nuclear factor TDP-43 and SR proteins promote in vitro and in vivo CFTR exon 9 skipping

Degradation of endocytosed epidermal growth factor and virally ubiquitinated major histocompatibility complex class I is independent of mammalian ESCRTII

Isolation and sequence of the granulin precursor cDNA from human bone marrow reveals tandem cysteine-rich granulin domains

Mutations in the endosomal ESCRTIII-complex subunit CHMP2B in frontotemporal dementia

Cloning and characterization of a novel cellular protein, TDP-43, that binds to human immunodeficiency virus type 1 TAR DNA sequence motifs

Structural and functional analysis of a promoter of the human granulin/epithelin gene

Localization of a highly active pool of type II phosphatidylinositol 4-kinase in a p97/valosin-containing-protein-rich fraction of the endoplasmic reticulum

A locus on human chromosome 20 contains several genes expressing protease inhibitor domains with homology to whey acidic protein

The growth factor granulin interacts with cyclin T1 and modulates P-TEFb-dependent transcription

Microglia and neuroinflammation: a pathological perspective

P2888

P304

7

http://www.w3.org/2001/XMLSchema#string

P31

scholarly article

P356

10.1186/1742-2094-4-7

http://www.w3.org/2001/XMLSchema#string

P407

P433

1

http://www.w3.org/2001/XMLSchema#string

P478

4

http://www.w3.org/2001/XMLSchema#string

P50

Dennis W. Dickson

P5008

P577

2007-02-11T00:00:00Z

http://www.w3.org/2001/XMLSchema#dateTime

P5875

6514398

http://www.w3.org/2001/XMLSchema#string

P6179

1029993324

http://www.w3.org/2001/XMLSchema#string

P698

17291356

http://www.w3.org/2001/XMLSchema#string

P921

P932

1805428

http://www.w3.org/2001/XMLSchema#string