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Genetical genomic determinants of alcohol consumption in rats and humans

Genetical genomic determinants of alcohol consumption in rats and humans

http://www.wikidata.org/entity/Q21245326

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NCK2 is significantly associated with opiates addiction in African-origin men Drosophila and Caenorhabditis elegans as Discovery Platforms for Genes Involved in Human Alcohol Use Disorder Molecular and neurologic responses to chronic alcohol use P2X4 receptors (P2X4Rs) represent a novel target for the development of drugs to prevent and/or treat alcohol use disorders Proteomic approaches and identification of novel therapeutic targets for alcoholism Introduction to sequencing the brain transcriptome Recent advances in the discovery and preclinical testing of novel compounds for the prevention and/or treatment of alcohol use disorders.A Genetic Animal Model of Alcoholism for Screening Medications to Treat Addiction.From integrative genomics to systems genetics in the rat to link genotypes to phenotypes Epigenetic Modifications, Alcoholic Brain and Potential Drug Targets Laboratory models available to study alcohol-induced organ damage and immune variations: choosing the appropriate model GABAergic gene expression in postmortem hippocampus from alcoholics and cocaine addicts; corresponding findings in alcohol-naïve P and NP rats Alcohol-induced serotonergic modulation: the role of histone deacetylases Genome-wide association study of alcohol dependence implicates KIAA0040 on chromosome 1q Alcohol, stress hormones, and the prefrontal cortex: a proposed pathway to the dark side of addiction.Rat models of post-irradiation recovery of spermatogenesis: interstrain differences.Differences in radiation sensitivity of recovery of spermatogenesis between rat strains Animal models for medications development targeting alcohol abuse using selectively bred rat lines: neurobiological and pharmacological validity Pharmacological insights into the role of P2X4 receptors in behavioural regulation: lessons from ivermectin.Convergent functional genomic studies of ω-3 fatty acids in stress reactivity, bipolar disorder and alcoholism.Multi-species data integration and gene ranking enrich significant results in an alcoholism genome-wide association study Identifying genes for neurobehavioural traits in rodents: progress and pitfalls Contribution of P2X4 receptors to ethanol intake in male C57BL/6 mice.Recent advances in genetics of the spontaneously hypertensive rat.Genetics and genomics of alcohol sensitivity Acute intravenous synaptamine complex variant KB220™ "normalizes" neurological dysregulation in patients during protracted abstinence from alcohol and opiates as observed using quantitative electroencephalographic and genetic analysis for reward pol A comparison of selected quantitative trait loci associated with alcohol use phenotypes in humans and mouse models.Genetical genomic analysis of complex phenotypes using the PhenoGen website Evaluating gene expression in C57BL/6J and DBA/2J mouse striatum using RNA-Seq and microarrays Family origin and mortality: prospective Finnish cohort study.Potential translational targets revealed by linking mouse grooming behavioral phenotypes to gene expression using public databases.Ivermectin antagonizes ethanol inhibition in purinergic P2X4 receptors Rapid temporal changes in the expression of a set of neuromodulatory genes during alcohol withdrawal in the dorsal vagal complex: molecular evidence of homeostatic disturbance The neurobiology of alcohol consumption and alcoholism: an integrative history Prenatal and postnatal ethanol experiences modulate consumption of the drug in rat pups, without impairment in the granular cell layer of the main olfactory bulb.GABAA receptor subtype involvement in addictive behaviour.Mpdz expression in the caudolateral substantia nigra pars reticulata is crucially involved in alcohol withdrawal Ethanol is a fast channel inhibitor of P2X4 receptors Making organisms model human behavior: situated models in North-American alcohol research, since 1950.Implication of the purinergic system in alcohol use disorders.

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P2860

Genetical genomic determinants of alcohol consumption in rats and humans

http://www.wikidata.org/entity/Q21245326

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2009 nî lūn-bûn

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2009 թուականին հրատարակուած գիտական յօդուած

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2009 թվականին հրատարակված գիտական հոդված

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2009年の論文

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2009年学术文章

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2009年学术文章

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2009年学术文章

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2009年学术文章

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2009年学术文章

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2009年學術文章

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Genetical genomic determinants of alcohol consumption in rats and humans

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Genetical genomic determinants of alcohol consumption in rats and humans

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Genetical genomic determinants of alcohol consumption in rats and humans

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Genetical genomic determinants of alcohol consumption in rats and humans

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Genetical genomic determinants of alcohol consumption in rats and humans

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Genetical genomic determinants of alcohol consumption in rats and humans

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Genetical genomic determinants of alcohol consumption in rats and humans

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Genetical genomic determinants of alcohol consumption in rats and humans

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Genetical genomic determinants of alcohol consumption in rats and humans

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Genetical genomic determinants of alcohol consumption in rats and humans

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Genetical genomic determinants of alcohol consumption in rats and humans

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Genetical genomic determinants of alcohol consumption in rats and humans

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Boris Tabakoff

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Colin Hodgkinson

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George Koob

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Bioconductor: open software development for computational biology and bioinformatics

Activated Cdc42-associated kinase 1 is a component of EGF receptor signaling complex and regulates EGF receptor degradation

Requirement of central ghrelin signaling for alcohol reward

BLAT--the BLAST-like alignment tool

Genetic linkage analysis supports the presence of two susceptibility loci for alcoholism and heavy drinking on chromosome 1p22.1-11.2 and 1q21.3-24.2

The structure of haplotype blocks in the human genome

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Phosphorylation-dependent regulation of Kv2.1 Channel activity at tyrosine 124 by Src and by protein-tyrosine phosphatase epsilon

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Heather Richardson

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alcohol consumption

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