about
AXIN:GSK3:CK1alpha:ub-APC:PP2A:AMER1 complexp-AXIN:GSK3 del304-316:CK1alpha:APC:PP2A:AMER1 complexp-AXIN:GSK3:CK1alpha:ub-APC:PP2A:AMER1 complexp-S33;S37;T41;S45 CTNNB1:p-AXIN:CK1alpha:GSK3B:phospho-ub-APC (20 aa repeat region):PP2A:AMER1 complexp-S33,S37,T41,S45 CTNNB1:p-AXIN:CK1alpha:GSK3B:phospho-ub-APC (20 aa repeat region):PP2A:AMER1 complexp-AXIN:CK1alpha:GSK3B:phospho-APC (20 aa repeat region):PP2A:AMER1 complexAPC truncation mutants have impaired AXIN bindingAXIN mutants destabilize the destruction complexExpression of AMER1 geneAssembly of the destruction complexBeta-catenin is released from the destruction complex
P527
P688
Amer1/WTX couples Wnt-induced formation of PtdIns(4,5)P2 to LRP6 phosphorylationAMER1 regulates the distribution of the tumor suppressor APC between microtubules and the plasma membraneStructural and functional characterization of the Wnt inhibitor APC membrane recruitment 1 (Amer1)Wilms tumor suppressor WTX negatively regulates WNT/beta-catenin signaling
P921
Q50256117-F02B75D7-E443-4F04-918E-FA304ACE0BEFQ50256128-6D60E22C-EDD2-45B7-9AFB-ED78B19D1268Q50273400-9169DABF-AD0B-4D10-9EB9-921280B158C9Q50273415-0F193C29-0C62-40EF-A9EE-B459557715F8Q50273416-56EFDE95-070C-43D2-A4DE-CD88CE1C3F1CQ50273421-14788857-D12E-431F-80CC-0E9E76FD8389Q50288857-08CD7CBA-C7D9-4289-B30E-0C6F5559967BQ50288860-600CDBA4-D0E8-407C-ACCB-389660EC9CC2Q50298704-73CD72F4-2ED2-47A1-81C2-3BE2D9CB677AQ50298707-45737DF0-16A8-4519-B578-30B2D5E528DDQ50298744-1805F4DF-D95E-47F3-82C4-99FDF9B699C5
P527
description
Protein in Homo sapiens
@de
mammalian protein found in Homo sapiens
@en
protein
@id
proteinë
@sq
proteïne in APC membrane recruitment protein 1
@nl
protèin
@ace
بروتين في الإنسان العاقل
@ar
name
APC membrane recruitment protein 1
@en
type
label
APC membrane recruitment protein 1
@en
altLabel
AMER1
@en
RP11-403E24.2
@en
Wilms tumor gene on the X chromosome protein
@en
Wilms tumor on the X
@en
adenomatous polyposis coli membrane recruitment 1
@en
family with sequence similarity 123B
@en
protein FAM123B
@en
prefLabel
APC membrane recruitment protein 1
@en
P638
P680
P681
P682
P352
P637
P31
P352
P637
P638
P680
P681
P682
P702
P703
P705
ENSP00000364003