Wilms tumor suppressor WTX negatively regulates WNT/beta-catenin signaling
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A novel role for Wnt/Ca2+ signaling in actin cytoskeleton remodeling and cell motility in prostate cancerA lentivirus-mediated genetic screen identifies dihydrofolate reductase (DHFR) as a modulator of beta-catenin/GSK3 signalingAmer1/WTX couples Wnt-induced formation of PtdIns(4,5)P2 to LRP6 phosphorylationThe ubiquitin-specific protease USP34 regulates axin stability and Wnt/β-catenin signalingAmer2 protein is a novel negative regulator of Wnt/β-catenin signaling involved in neuroectodermal patterningStructural and functional characterization of the Wnt inhibitor APC membrane recruitment 1 (Amer1)Multiple Wnt/ß-catenin responsive enhancers align with the MYC promoter through long-range chromatin loopsErbB2 receptor controls microtubule capture by recruiting ACF7 to the plasma membrane of migrating cells.Adenomatous polyposis coli (APC) membrane recruitment 3, a member of the APC membrane recruitment family of APC-binding proteins, is a positive regulator of Wnt-β-catenin signallingThe Axin1 scaffold protein promotes formation of a degradation complex for c-MycWNT5A is regulated by PAX2 and may be involved in blastemal predominant Wilms tumorigenesisLGR6 is a high affinity receptor of R-spondins and potentially functions as a tumor suppressorCITED1 expression in Wilms' tumor and embryonic kidneyWnt modulators in the biotech pipelineComprehensive molecular characterization of human colon and rectal cancerWnt/beta-catenin signaling: components, mechanisms, and diseasesWnt signaling: the good and the badIs Wilms tumor a candidate neoplasia for treatment with WNT/β-catenin pathway modulators?--A report from the renal tumors biology-driven drug development workshopGSK-3 as potential target for therapeutic intervention in cancerBili inhibits Wnt/beta-catenin signaling by regulating the recruitment of axin to LRP6Axin cancer mutants form nanoaggregates to rewire the Wnt signaling networkThe β-catenin destruction complexPituitary homeobox 2 (PITX2) protects renal cancer cell lines against doxorubicin toxicity by transcriptional activation of the multidrug transporter ABCB1Activated Wnt/beta-catenin signaling in melanoma is associated with decreased proliferation in patient tumors and a murine melanoma modelWIKI4, a novel inhibitor of tankyrase and Wnt/ß-catenin signalingdifferent Roles for the axin interactions with the SAMP versus the second twenty amino acid repeat of adenomatous polyposis coliDerricin and derricidin inhibit Wnt/β-catenin signaling and suppress colon cancer cell growth in vitroThe WTX tumor suppressor regulates mesenchymal progenitor cell fate specificationLRP6 transduces a canonical Wnt signal independently of Axin degradation by inhibiting GSK3's phosphorylation of beta-cateninMolecular characterization of Wilms' tumor from a resource-constrained region of sub-Saharan AfricaRace disparities in Wilms tumor incidence and biology.FAM123A binds to microtubules and inhibits the guanine nucleotide exchange factor ARHGEF2 to decrease actomyosin contractility.Functional inactivation of the WTX gene is not a frequent event in Wilms' tumors.A beta-catenin/TCF-coordinated chromatin loop at MYC integrates 5' and 3' Wnt responsive enhancersMutations in the WTX-gene are found in some high-grade microsatellite instable (MSI-H) colorectal cancersSingle locus affects embryonic segment polarity and multiple aspects of an adult evolutionary noveltyThe WTX/AMER1 gene family: evolution, signature and functionGSK3: a multifaceted kinase in Wnt signaling.Predicting relapse in favorable histology Wilms tumor using gene expression analysis: a report from the Renal Tumor Committee of the Children's Oncology Group.A novel Wilms tumor 1 (WT1) target gene negatively regulates the WNT signaling pathway
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Wilms tumor suppressor WTX negatively regulates WNT/beta-catenin signaling
description
2007 թուականի Մայիսին հրատարակուած գիտական յօդուած
@hyw
2007 թվականի մայիսին հրատարակված գիտական հոդված
@hy
article publié dans la revue scientifique Science
@fr
artículu científicu espublizáu en 2007
@ast
im Mai 2007 veröffentlichter wissenschaftlicher Artikel
@de
scientific journal article
@en
vedecký článok (publikovaný 2007/05/18)
@sk
vědecký článek publikovaný v roce 2007
@cs
wetenschappelijk artikel (gepubliceerd op 2007/05/18)
@nl
наукова стаття, опублікована в травні 2007
@uk
name
Wilms tumor suppressor WTX negatively regulates WNT/beta-catenin signaling
@ast
Wilms tumor suppressor WTX negatively regulates WNT/beta-catenin signaling
@en
Wilms tumor suppressor WTX negatively regulates WNT/beta-catenin signaling
@nl
type
label
Wilms tumor suppressor WTX negatively regulates WNT/beta-catenin signaling
@ast
Wilms tumor suppressor WTX negatively regulates WNT/beta-catenin signaling
@en
Wilms tumor suppressor WTX negatively regulates WNT/beta-catenin signaling
@nl
prefLabel
Wilms tumor suppressor WTX negatively regulates WNT/beta-catenin signaling
@ast
Wilms tumor suppressor WTX negatively regulates WNT/beta-catenin signaling
@en
Wilms tumor suppressor WTX negatively regulates WNT/beta-catenin signaling
@nl
P2093
P356
P1433
P1476
Wilms tumor suppressor WTX negatively regulates WNT/beta-catenin signaling
@en
P2093
Charlotte Hubbert
Jason D. Berndt
Michael B. Major
Michael J. Maccoss
Nathan D. Camp
Ning Zheng
Randall T. Moon
Seth J. Goldenberg
Travis L. Biechele
Xianhua Yi
P304
P356
10.1126/SCIENCE/1141515
P407
P577
2007-05-18T00:00:00Z