Mismatch repair endonuclease PMS2

Mismatch repair endonuclease PMS2

Item
http://www.wikidata.org/entity/Q21980091
Pms2
P688
Differing patterns of genetic instability in mice deficient in the mismatch repair genes Pms2, Mlh1, Msh2, Msh3 and Msh6ATR kinase activation mediated by MutSalpha and MutLalpha in response to cytotoxic O6-methylguanine adductsMutS homolog 4 localization to meiotic chromosomes is required for chromosome pairing during meiosis in male and female micePms2 suppresses large expansions of the (GAA·TTC)n sequence in neuronal tissuesTumour susceptibility and spontaneous mutation in mice deficient in Mlh1, Pms1 and Pms2 DNA mismatch repairRole for mismatch repair proteins Msh2, Mlh1, and Pms2 in immunoglobulin class switching shown by sequence analysis of recombination junctionsReduced isotype switching in splenic B cells from mice deficient in mismatch repair enzymesMlh1 mediates tissue-specific regulation of mitotic recombinationDifferent mismatch repair deficiencies all have the same effects on somatic hypermutation: intact primary mechanism accompanied by secondary modificationsElevated mutant frequencies and increased C : G-->T : A transitions in Mlh1-/- versus Pms2-/- murine small intestinal epithelial cellsDifferent mutator phenotypes in Mlh1- versus Pms2-deficient miceContributions by MutL homologues Mlh3 and Pms2 to DNA mismatch repair and tumor suppression in the mouseAltered spectra of hypermutation in antibodies from mice deficient for the DNA mismatch repair protein PMS2
P921

Mismatch repair endonuclease PMS2

Item
http://www.wikidata.org/entity/Q21980091
description
mouse protein (annotated by UniProtKB/Swiss-Prot P54279)
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proteinë
@sq
proteïne
@nl
بروتين في فأر المنازل
@ar
name
Mismatch repair endonuclease PMS2
@en
type
label
Mismatch repair endonuclease PMS2
@en
altLabel
DNA mismatch repair protein PMS2
@en
PMS1 protein homolog 2
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prefLabel
Mismatch repair endonuclease PMS2
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P31
P352
P361
P527
P680
P681
P682
P702
P703
P352
P31
P352
P361
P527
P680
P681
P682
P702
P703