Excision repair cross-complementing rodent repair deficiency, complementation group 1
about
P688
The structure-specific endonuclease Ercc1-Xpf is required for targeted gene replacement in embryonic stem cellsEvolution and mutagenesis of the mammalian excision repair gene ERCC-1Disruption of TTDA results in complete nucleotide excision repair deficiency and embryonic lethalityAdaptive stress response in segmental progeria resembles long-lived dwarfism and calorie restriction in miceUSP45 deubiquitylase controls ERCC1-XPF endonuclease-mediated DNA damage responsesA new progeroid syndrome reveals that genotoxic stress suppresses the somatotroph axisDisruption of mouse ERCC1 results in a novel repair syndrome with growth failure, nuclear abnormalities and senescenceReduced hematopoietic reserves in DNA interstrand crosslink repair-deficient Ercc1-/- miceNucleotide excision repair gene (ERCC1) deficiency causes G(2) arrest in hepatocytes and a reduction in liver binucleation: the role of p53 and p21Deletion of the nucleotide excision repair gene Ercc1 reduces immunoglobulin class switching and alters mutations near switch recombination junctionsMice with skin-specific DNA repair gene (Ercc1) inactivation are hypersensitive to ultraviolet irradiation-induced skin cancer and show more rapid actinic progressionThe involvement of key DNA repair pathways in the formation of chromosome rearrangements in embryonic stem cellsDeletion of genes implicated in protecting the integrity of male germ cells has differential effects on the incidence of DNA breaks and germ cell lossRTEL1 dismantles T loops and counteracts telomeric G4-DNA to maintain telomere integrityThe role of nucleotide excision repair in protecting embryonic stem cells from genotoxic effects of UV-induced DNA damageMice with DNA repair gene (ERCC-1) deficiency have elevated levels of p53, liver nuclear abnormalities and die before weaningThe structure-specific endonuclease Ercc1-Xpf is required to resolve DNA interstrand cross-link-induced double-strand breaksDNA repair gene Ercc1 is essential for normal spermatogenesis and oogenesis and for functional integrity of germ cell DNA in the mouse
P921
Q24291899-02F88FAB-8FE2-428F-B743-CFFAD4EE5C67Q24297867-11F60709-7B81-40B9-AC61-7D29D7CB795FQ24339524-34610FD3-B0F4-4A8E-8866-67BD05BEC422Q27315126-46EFA173-292A-425F-BBCB-D767A46EC03AQ28115910-BB5695C3-279A-47FA-9D60-6E7CCE1EC63EQ28280037-12F01BAC-CF8F-4AE9-8BB2-D5DD7C1B3939Q28505334-552FA710-48FF-4FDC-8AA6-BA40157FD4C0Q28506106-248A0F61-67AD-40DB-83F3-79F7AC437127Q28507454-7A2704D9-F43E-44BF-8162-538FA7B40E79Q28508643-78CE26E9-2DEB-4B47-98DC-46BB41ED70B1Q28510546-5D771745-E2D5-48B9-A8E6-216C03F9B8B4Q28511995-C54192F1-B634-49BD-A529-4D1D8C856866Q28513002-FBF26021-46C2-4BDA-8044-CCD55EEF8A3EQ28513037-B59D90DB-1014-472B-A3A5-C2980E319EEDQ28586234-86F86F29-94BC-41AA-8B2F-5EDBC2274280Q28587990-D008F479-0FFC-4146-9F26-D0D36DA1A790Q28592473-00B6D0DE-E82D-423A-9611-E7C2460A43FEQ28592529-1D7A1CE9-050A-4B3A-BE7D-881EC4E5FD7B
P921
Excision repair cross-complementing rodent repair deficiency, complementation group 1
description
mammalian protein found in Mus musculus
@en
protein
@id
proteinë
@sq
proteïne in Excision repair cr ...... iency, complementation group 1
@nl
protèin
@ace
بروتين في فأر المنازل
@ar
name
Excision repair cross-complementing rodent repair deficiency, complementation group 1
@en
Excision repair cross-complementing rodent repair deficiency, complementation group 1
@nl
type
label
Excision repair cross-complementing rodent repair deficiency, complementation group 1
@en
Excision repair cross-complementing rodent repair deficiency, complementation group 1
@nl
altLabel
DNA excision repair protein ERCC-1
@en
Ercc1
@en
prefLabel
Excision repair cross-complementing rodent repair deficiency, complementation group 1
@en
Excision repair cross-complementing rodent repair deficiency, complementation group 1
@nl
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NP_001120796
XP_006539602
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ENSMUSP00000003645
ENSMUSP00000125655
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ENSMUSP00000135767