Reduced hematopoietic reserves in DNA interstrand crosslink repair-deficient Ercc1-/- mice - Wikidata - wikimedia - TriplyDB

Reduced hematopoietic reserves in DNA interstrand crosslink repair-deficient Ercc1-/- mice

Reduced hematopoietic reserves in DNA interstrand crosslink repair-deficient Ercc1-/- mice

http://www.wikidata.org/entity/Q28506106

about

Altered hematopoiesis in mice lacking DNA polymerase mu is due to inefficient double-strand break repair Molecular pathogenesis and clinical management of Fanconi anemia How the fanconi anemia pathway guards the genome First reported patient with human ERCC1 deficiency has cerebro-oculo-facio-skeletal syndrome with a mild defect in nucleotide excision repair and severe developmental failure Aging of hematopoietic stem cells: DNA damage and mutations?DNA Damage: A Main Determinant of Vascular Aging Mechanism and regulation of incisions during DNA interstrand cross-link repair Adaptive stress response in segmental progeria resembles long-lived dwarfism and calorie restriction in mice Balancing self-renewal against genome preservation in stem cells: How do they manage to have the cake and eat it too?Physiological consequences of defects in ERCC1-XPF DNA repair endonuclease ERCC1-XPF endonuclease facilitates DNA double-strand break repair The GIY-YIG Type Endonuclease Ankyrin Repeat and LEM Domain-Containing Protein 1 (ANKLE1) Is Dispensable for Mouse Hematopoiesis Impaired spermatogenesis and elevated spontaneous tumorigenesis in xeroderma pigmentosum group A gene (Xpa)-deficient mice.Prognostic significance of ERCC1 expression in postoperative patients with gastric cancer.Quiescent hematopoietic stem cells accumulate DNA damage during aging that is repaired upon entry into cell cycle Hematopoietic stem cell defects in mice with deficiency of Fancd2 or Usp1.Broad segmental progeroid changes in short-lived Ercc1(-/Δ7) mice Epigenetic control of hematopoietic stem cell aging the case of Ezh2.Congenital bone marrow failure in DNA-PKcs mutant mice associated with deficiencies in DNA repair.A mouse model of accelerated liver aging caused by a defect in DNA repair Comparison of mice with accelerated aging caused by distinct mechanisms Extended longevity mechanisms in short-lived progeroid mice: identification of a preservative stress response associated with successful aging.Accelerated aging of intervertebral discs in a mouse model of progeria.Fancb deficiency impairs hematopoietic stem cell function.Stem Cell-Specific Mechanisms Ensure Genomic Fidelity within HSCs and upon Aging of HSCs.Cell autonomous and nonautonomous mechanisms drive hematopoietic stem/progenitor cell loss in the absence of DNA repair.How does suppression of IGF-1 signaling by DNA damage affect aging and longevity?DNA damage drives accelerated bone aging via an NF-κB-dependent mechanism.Non-erythroid alpha spectrin prevents telomere dysfunction after DNA interstrand cross-link damage Contributions of DNA interstrand cross-links to aging of cells and organisms.The role of DNA damage repair in aging of adult stem cells Myelodysplastic syndrome: an inability to appropriately respond to damaged DNA?Stem cells and aging in the hematopoietic system.Tissue-specific accelerated aging in nucleotide excision repair deficiency Effect of aging on stem cells.Polycomb group proteins in hematopoietic stem cell aging and malignancies.The Fanconi anaemia pathway orchestrates incisions at sites of crosslinked DNA.Functional dysregulation of stem cells during aging: a focus on skeletal muscle stem cells.Resilient and resourceful: genome maintenance strategies in hematopoietic stem cells.Fanconi Anemia: A DNA repair disorder characterized by accelerated decline of the hematopoietic stem cell compartment and other features of aging.

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Reduced hematopoietic reserves in DNA interstrand crosslink repair-deficient Ercc1-/- mice

http://www.wikidata.org/entity/Q28506106

description

2005 թուականի Փետրուարին հրատարակուած գիտական յօդուած

@hyw

2005 թվականի փետրվարին հրատարակված գիտական հոդված

@hy

artículu científicu espublizáu en 2005

@ast

im Februar 2005 veröffentlichter wissenschaftlicher Artikel

@de

scientific journal article

@en

vedecký článok (publikovaný 2005/02/23)

@sk

vědecký článek publikovaný v roce 2005

@cs

wetenschappelijk artikel (gepubliceerd op 2005/02/23)

@nl

наукова стаття, опублікована в лютому 2005

@uk

مقالة علمية (نشرت في 23-2-2005)

@ar

name

Reduced hematopoietic reserves ...... repair-deficient Ercc1-/- mice

@ast

Reduced hematopoietic reserves ...... repair-deficient Ercc1-/- mice

@en

Reduced hematopoietic reserves ...... repair-deficient Ercc1-/- mice

@nl

type

label

Reduced hematopoietic reserves ...... repair-deficient Ercc1-/- mice

@ast

Reduced hematopoietic reserves ...... repair-deficient Ercc1-/- mice

@en

Reduced hematopoietic reserves ...... repair-deficient Ercc1-/- mice

@nl

prefLabel

Reduced hematopoietic reserves ...... repair-deficient Ercc1-/- mice

@ast

Reduced hematopoietic reserves ...... repair-deficient Ercc1-/- mice

@en

Reduced hematopoietic reserves ...... repair-deficient Ercc1-/- mice

@nl

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SJ.EMBOJ.7600542

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The EMBO Journal

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Reduced hematopoietic reserves ...... repair-deficient Ercc1-/- mice

@en

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Astrid S. Lalai

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Claudia Heijmans-Antonissen

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Ivo P. Touw

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Jan H. J. Hoeijmakers

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Joanna M. Prasher

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Laura J. Niedernhofer

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Robert E. Ploemacher

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P2860

Mutational analysis of the human nucleotide excision repair gene ERCC1

A biomarker that identifies senescent human cells in culture and in aging skin in vivo

Oxidants, oxidative stress and the biology of ageing

Deletion of Ku86 causes early onset of senescence in mice

Aging and genome maintenance: lessons from the mouse?

Reduced fertility and hypersensitivity to mitomycin C characterize Fancg/Xrcc9 null mice

Regulation of oxidative stress by ATM is required for self-renewal of haematopoietic stem cells

Disruption of mouse ERCC1 results in a novel repair syndrome with growth failure, nuclear abnormalities and senescence

Defective hematopoiesis and hepatic steatosis in mice with combined deficiencies of the genes encoding Fancc and Cu/Zn superoxide dismutase

Mice with DNA repair gene (ERCC-1) deficiency have elevated levels of p53, liver nuclear abnormalities and die before weaning

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861–871

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1549702

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10.1038/SJ.EMBOJ.7600542

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4

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8039300

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15692571

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Excision repair cross-complementing rodent repair deficiency, complementation group 1

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549615

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