about
P688
Selective associations with signaling proteins determine stimulatory versus costimulatory activity of NKG2DA new triggering receptor expressed on myeloid cells (Trem) family member, Trem-like 4, binds to dead cells and is a DNAX activation protein 12-linked marker for subsets of mouse macrophages and dendritic cellsIntegrin signaling in neutrophils and macrophages uses adaptors containing immunoreceptor tyrosine-based activation motifsPaired activating and inhibitory immunoglobulin-like receptors, MAIR-I and MAIR-II, regulate mast cell and macrophage activationCharacterization of TREM-3, an activating receptor on mouse macrophages: definition of a family of single Ig domain receptors on mouse chromosome 17Signal adaptor DAP10 associates with MDL-1 and triggers osteoclastogenesis in cooperation with DAP12Identification and characterization of a new pair of immunoglobulin-like receptors LMIR1 and 2 derived from murine bone marrow-derived mast cellsRhomboid domain-containing protein 3 is a negative regulator of TLR3-triggered natural killer cell activationSiglec-15 protein regulates formation of functional osteoclasts in concert with DNAX-activating protein of 12 kDa (DAP12)The immunoreceptor adapter protein DAP12 suppresses B lymphocyte-driven adaptive immune responses.OSCAR is a collagen receptor that costimulates osteoclastogenesis in DAP12-deficient humans and miceDAP12 couples c-Fms activation to the osteoclast cytoskeleton by recruitment of Syk.Essential role of DAP12 signaling in macrophage programming into a fusion-competent state.The signaling adapter protein DAP12 regulates multinucleation during osteoclast development.Clearance of apoptotic neurons without inflammation by microglial triggering receptor expressed on myeloid cells-2.Developmental neuronal death in hippocampus requires the microglial CD11b integrin and DAP12 immunoreceptor.Impaired synaptic function in the microglial KARAP/DAP12-deficient mouse.Ly-49D and Ly-49H associate with mouse DAP12 and form activating receptors.TREM2 Is a Receptor for β-Amyloid that Mediates Microglial Function.A DAP12-dependent signal promotes pro-inflammatory polarization in microglia following nerve injury and exacerbates degeneration of injured neurons.
P921
Q28214530-3BB1F974-471E-4EA9-ABF0-8AE061A3D8E8Q28511097-7150221A-4ABE-4385-BBE1-EE9A523C4B1AQ28585779-E5EBB646-00A2-4B6D-B81E-724EF5F77674Q28586601-846181F7-3331-42F8-9FC2-75ACD5BB6E24Q28589523-5B3A7412-0D4E-4F36-A96A-6D30827BD13BQ28590300-C49CEF0E-D66C-4FB7-9FC5-8B42A416CECBQ28593194-2C9E5950-035A-46FC-A4CD-94730D05B820Q28593417-E38A8D67-B8D0-4D6D-85E9-F2D39A2AD777Q28594672-11A6DB64-F682-41AB-9F56-3C567D8CCE4AQ35144618-91A0C05D-3517-4336-BA85-4DFFD38E9A34Q35187075-7F609229-18DC-4038-8EB3-D4DBB797E7C0Q36977266-D3469F46-60F3-4F60-818D-2E102A6008C0Q37171072-E25E1D81-10B7-4FAF-88F0-ED86239ECD79Q40589041-711F67D5-4E07-4A3A-B7E0-81B35708DD88Q42057034-F60A0980-66D2-4473-B351-E3DFD8AD1FBFQ44207850-98D2ABF0-AF87-4A77-8B90-C274F59E4E90Q45188927-1CFC4BF1-03DE-47DB-80DD-5CCD5F813FDCQ47910176-AA49E00C-771B-4964-8BFB-7643DC58A804Q51764852-E48D3FB7-EE92-4E58-AC00-DD1E21121E92Q53605456-AB95F372-559F-4F06-BE29-97E0F6DECCBC
P921
description
mammalian protein found in Mus musculus
@en
protein
@id
proteinë
@sq
proteïne in TYRO protein tyrosine kinase binding protein
@nl
protèin
@ace
بروتين في فأر المنازل
@ar
name
TYRO protein tyrosine kinase binding protein
@en
type
label
TYRO protein tyrosine kinase binding protein
@en
altLabel
DNAX-activation protein 12
@en
KAR-associated protein
@en
TYRO protein tyrosine kinase-binding protein
@en
Tyrobp
@en
killer cell activating receptor associated protein
@en
killer-activating receptor-associated protein
@en
prefLabel
TYRO protein tyrosine kinase binding protein
@en
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ENSMUSP00000032800
ENSMUSP00000146494
ENSMUSP00000146653