The prion hypothesis in Parkinson's disease: Braak to the future
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Infectivity versus Seeding in Neurodegenerative Diseases Sharing a Prion-Like MechanismStem cell transplantation therapy in Parkinson's diseaseThe clinical characteristics of dementia with Lewy bodies and a consideration of prodromal diagnosisMolecular chaperones and protein folding as therapeutic targets in Parkinson's disease and other synucleinopathiesColonic Oxidative and Mitochondrial Function in Parkinson's Disease and Idiopathic REM Sleep Behavior Disorder.Network Neurodegeneration in Alzheimer's Disease via MRI Based Shape Diffeomorphometry and High-Field AtlasingExploring Braak's Hypothesis of Parkinson's Disease.Colonic mucosal a-synuclein lacks specificity as a biomarker for Parkinson disease.The brainstem pathologies of Parkinson's disease and dementia with Lewy bodies.Bacterial Chaperones CsgE and CsgC Differentially Modulate Human α-Synuclein Amyloid Formation via Transient ContactsBrain mediators of systemic oxidative stress on perceptual impairments in Parkinson's disease.Proaggregant nuclear factor(s) trigger rapid formation of α-synuclein aggregates in apoptotic neurons.FTY720/Fingolimod Reduces Synucleinopathy and Improves Gut Motility in A53T Mice: CONTRIBUTIONS OF PRO-BRAIN-DERIVED NEUROTROPHIC FACTOR (PRO-BDNF) AND MATURE BDNF.Pathogenesis-targeted, disease-modifying therapies in Parkinson disease.Alimentary, my dear Watson? The challenges of enteric α-synuclein as a Parkinson's disease biomarker.The pathomechanisms underlying Parkinson's disease.Latest concept of Lewy body disease.Neuropathology of multiple system atrophy: new thoughts about pathogenesis.Lewy body disease and dementia with Lewy bodies.Protein Transmission, Seeding and Degradation: Key Steps for α-Synuclein Prion-Like PropagationIs Parkinson's disease truly a prion-like disorder? An appraisal of current evidence.The relevance of pre-motor symptoms in Parkinson's disease.Impaired endo-lysosomal membrane integrity accelerates the seeding progression of α-synuclein aggregates.ɑ-Synuclein strains and the variable pathologies of synucleinopathies.An update on potential therapeutic strategies for Parkinson's disease based on pathogenic mechanisms.Key Points Concerning Amyloid Infectivity and Prion-Like Neuronal InvasionVagal neurocircuitry and its influence on gastric motilityRole of neurotoxicants and traumatic brain injury in α-synuclein protein misfolding and aggregation.Looking at the recent advances in understanding α-synuclein and its aggregation through the proteoform prism.Alpha-Synuclein to the Rescue: Immune Cell Recruitment by Alpha-Synuclein during Gastrointestinal Infection.Beyond Krabbe's disease: The potential contribution of galactosylceramidase deficiency to neuronal vulnerability in late-onset synucleinopathiesCould α-synuclein amyloid-like aggregates trigger a prionic neuronal invasion?α-Synuclein in gut endocrine cells and its implications for Parkinson's diseasePattern of Reduced Functional Connectivity and Structural Abnormalities in Parkinson's Disease: An Exploratory StudySomething wicked this way comes: huntingtin.Subcellular Parkinson's Disease-Specific Alpha-Synuclein Species Show Altered Behavior in Neurodegeneration.Phosphorylated exogenous alpha-synuclein fibrils exacerbate pathology and induce neuronal dysfunction in mice.A Nigro-Vagal Pathway Controls Gastric Motility and Is Affected in a Rat Model of Parkinsonism.Lesion of medullary catecholaminergic neurons is associated with cardiovascular dysfunction in rotenone-induced Parkinson's disease rats.α-Synuclein in the colon and premotor markers of Parkinson disease in neurologically normal subjects.
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P2860
The prion hypothesis in Parkinson's disease: Braak to the future
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2013 nî lūn-bûn
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2013 թուականի Մայիսին հրատարակուած գիտական յօդուած
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2013 թվականի մայիսին հրատարակված գիտական հոդված
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2013年の論文
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2013年論文
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2013年論文
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2013年論文
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2013年論文
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2013年論文
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2013年论文
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The prion hypothesis in Parkinson's disease: Braak to the future
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The prion hypothesis in Parkinson's disease: Braak to the future
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The prion hypothesis in Parkinson's disease: Braak to the future
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The prion hypothesis in Parkinson's disease: Braak to the future
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The prion hypothesis in Parkinson's disease: Braak to the future
@ast
The prion hypothesis in Parkinson's disease: Braak to the future
@en
The prion hypothesis in Parkinson's disease: Braak to the future
@en-gb
The prion hypothesis in Parkinson's disease: Braak to the future
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The prion hypothesis in Parkinson's disease: Braak to the future
@ast
The prion hypothesis in Parkinson's disease: Braak to the future
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The prion hypothesis in Parkinson's disease: Braak to the future
@en-gb
The prion hypothesis in Parkinson's disease: Braak to the future
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The prion hypothesis in Parkinson's disease: Braak to the future
@en
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Lili-Naz Hazrati
Patricia L Brooks
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10.1186/2051-5960-1-2
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P577
2013-05-08T00:00:00Z
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1015489171