The histone variant macroH2A1 marks repressed autosomal chromatin, but protects a subset of its target genes from silencing
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Immunopositivity for histone macroH2A1 isoforms marks steatosis-associated hepatocellular carcinomaDistinct distribution of ectopically expressed histone variants H2A.Bbd and MacroH2A in open and closed chromatin domainsHistone variant H2A.Bbd is associated with active transcription and mRNA processing in human cellsATRX-mediated chromatin association of histone variant macroH2A1 regulates α-globin expressionThe atypical histone macroH2A1.2 interacts with HER-2 protein in cancer cellsmacroH2A1 histone variant represses rDNA transcriptionMacro histone variants are critical for the differentiation of human pluripotent cellsHistone variants as emerging regulators of embryonic stem cell identityMolecular turnover, the H3.3 dilemma and organismal aging (hypothesis)Every amino acid matters: essential contributions of histone variants to mammalian development and diseaseExpression and functionality of histone H2A variants in cancerA system for genome-wide histone variant dynamics in ES cells reveals dynamic MacroH2A2 replacement at promotersMacroH2A histone variants act as a barrier upon reprogramming towards pluripotencySplicing switch of an epigenetic regulator by RNA helicases promotes tumor-cell invasivenessHistone variant macroH2A confers resistance to nuclear reprogramming.NSD3-NUT fusion oncoprotein in NUT midline carcinoma: implications for a novel oncogenic mechanism.Histone variants: dynamic punctuation in transcription.Histone variants: emerging players in cancer biology.The histone variant H2A.Bbd is enriched at sites of DNA synthesis.The histone variant MacroH2A1 regulates target gene expression in part by recruiting the transcriptional coregulator PELP1.Histone variant macroH2A1 deletion in mice causes female-specific steatosis.The histone H2A variant macroH2A1 does not localize to the centrosome.The linker region of macroH2A promotes self-association of nucleosomal arrays.Genome-wide analysis reveals PADI4 cooperates with Elk-1 to activate c-Fos expression in breast cancer cells.X chromosome inactivation and differentiation occur readily in ES cells doubly-deficient for macroH2A1 and macroH2A2.Histone variants in metazoan developmentQKI-mediated alternative splicing of the histone variant MacroH2A1 regulates cancer cell proliferationGenome-wide distribution of macroH2A1 histone variants in mouse liver chromatin.MacroH2A1.1 and PARP-1 cooperate to regulate transcription by promoting CBP-mediated H2B acetylation.Mice without macroH2A histone variants.Synergism between DNA methylation and macroH2A1 occupancy in epigenetic silencing of the tumor suppressor gene p16(CDKN2A).Epigenetic upregulation of lncRNAs at 13q14.3 in leukemia is linked to the In Cis downregulation of a gene cluster that targets NF-kB.The histone variant macroH2A suppresses melanoma progression through regulation of CDK8.Genome-wide analysis of the chromatin composition of histone H2A and H3 variants in mouse embryonic stem cellsRevealing histone variant induced changes via quantitative proteomicsA method for generating highly multiplexed ChIP-seq librariesEpigenetic mechanisms involved in developmental nutritional programming.Proteogenomics analysis reveals specific genomic orientations of distal regulatory regions composed by non-canonical histone variants.The nonhistone, N-terminal tail of an essential, chimeric H2A variant regulates mitotic H3-S10 dephosphorylation.MacroH2A1 regulates the balance between self-renewal and differentiation commitment in embryonic and adult stem cells.
P2860
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P2860
The histone variant macroH2A1 marks repressed autosomal chromatin, but protects a subset of its target genes from silencing
description
2010 nî lūn-bûn
@nan
2010 թուականի Յունուարին հրատարակուած գիտական յօդուած
@hyw
2010 թվականի հունվարին հրատարակված գիտական հոդված
@hy
2010年の論文
@ja
2010年論文
@yue
2010年論文
@zh-hant
2010年論文
@zh-hk
2010年論文
@zh-mo
2010年論文
@zh-tw
2010年论文
@wuu
name
The histone variant macroH2A1 ...... ts target genes from silencing
@ast
The histone variant macroH2A1 ...... ts target genes from silencing
@en
The histone variant macroH2A1 ...... ts target genes from silencing
@en-gb
The histone variant macroH2A1 ...... ts target genes from silencing
@nl
type
label
The histone variant macroH2A1 ...... ts target genes from silencing
@ast
The histone variant macroH2A1 ...... ts target genes from silencing
@en
The histone variant macroH2A1 ...... ts target genes from silencing
@en-gb
The histone variant macroH2A1 ...... ts target genes from silencing
@nl
prefLabel
The histone variant macroH2A1 ...... ts target genes from silencing
@ast
The histone variant macroH2A1 ...... ts target genes from silencing
@en
The histone variant macroH2A1 ...... ts target genes from silencing
@en-gb
The histone variant macroH2A1 ...... ts target genes from silencing
@nl
P2093
P2860
P3181
P356
P1433
P1476
The histone variant macroH2A1 ...... ts target genes from silencing
@en
P2093
Christine Yang
Kristine M Frizzell
Matthew J Gamble
Raga Krishnakumar
W Lee Kraus
P2860
P3181
P356
10.1101/GAD.1876110
P407
P577
2010-01-01T00:00:00Z