The histone variant macroH2A suppresses melanoma progression through regulation of CDK8. - Wikidata - wikimedia - TriplyDB

The histone variant macroH2A suppresses melanoma progression through regulation of CDK8.

The histone variant macroH2A suppresses melanoma progression through regulation of CDK8.

http://www.wikidata.org/entity/Q34676833

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Immunopositivity for histone macroH2A1 isoforms marks steatosis-associated hepatocellular carcinoma ATRX-mediated chromatin association of histone variant macroH2A1 regulates α-globin expression Macro histone variants are critical for the differentiation of human pluripotent cells Targeting NK Cells for Anticancer Immunotherapy: Clinical and Preclinical Approaches Global histone post-translational modifications and cancer: Biomarkers for diagnosis, prognosis and treatment?Progress in epigenetic histone modification analysis by mass spectrometry for clinical investigations Histone Modifications, Modifiers and Readers in Melanoma Resistance to Targeted and Immune Therapy Expression of CDK8 and CDK8-interacting Genes as Potential Biomarkers in Breast Cancer Chromatin Dynamics in Vivo: A Game of Musical Chairs Mediator kinase module and human tumorigenesis Targeting cyclin-dependent kinases in human cancers: from small molecules to Peptide inhibitors Chromatin dynamics during cellular reprogramming Every amino acid matters: essential contributions of histone variants to mammalian development and disease Expression and functionality of histone H2A variants in cancer Proteomics in epigenetics: new perspectives for cancer research Structure-kinetic relationship study of CDK8/CycC specific compounds Discovery of Potent, Selective, and Orally Bioavailable Small-Molecule Modulators of the Mediator Complex-Associated Kinases CDK8 and CDK19 Epigenetic determinants of metastasis Cyclin-dependent kinase 8 mediates chemotherapy-induced tumor-promoting paracrine activities.MicroRNA-101 is a potential prognostic indicator of laryngeal squamous cell carcinoma and modulates CDK8 Regulation of lipogenesis by cyclin-dependent kinase 8-mediated control of SREBP-1 The Mediator complex and transcription regulation Decreased expression of the chromatin remodeler ATRX associates with melanoma progression MacroH2A histone variants act as a barrier upon reprogramming towards pluripotency Splicing switch of an epigenetic regulator by RNA helicases promotes tumor-cell invasiveness Deregulation of F-box proteins and its consequence on cancer development, progression and metastasis.Histone variants and epigenetics.A Role for Histone H2B Variants in Endocrine-Resistant Breast Cancer.Mitogen-activated protein kinase signaling mediates phosphorylation of polycomb ortholog Cbx7.Histone variant macroH2A confers resistance to nuclear reprogramming.Tumor-suppressive effects of CDK8 in endometrial cancer cells.H19 Noncoding RNA, an Independent Prognostic Factor, Regulates Essential Rb-E2F and CDK8-β-Catenin Signaling in Colorectal Cancer.Mutation analysis of components of the Mediator kinase module in MED12 mutation-negative uterine leiomyomas.Histone variants: emerging players in cancer biology.The histone variant H2A.Bbd is enriched at sites of DNA synthesis.Epigenetics: an emerging player in gastric cancer Increased macroH2A1.1 expression correlates with poor survival of triple-negative breast cancer patients The histone variant MacroH2A1 regulates target gene expression in part by recruiting the transcriptional coregulator PELP1.A Kinase-Independent Role for Cyclin-Dependent Kinase 19 in p53 Response.Histone variant H3F3A promotes lung cancer cell migration through intronic regulation

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P2860

The histone variant macroH2A suppresses melanoma progression through regulation of CDK8.

http://www.wikidata.org/entity/Q34676833

description

2010 nî lūn-bûn

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2010 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած

@hyw

2010 թվականի դեկտեմբերին հրատարակված գիտական հոդված

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2010年の論文

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2010年論文

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2010年論文

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2010年論文

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2010年論文

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2010年論文

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2010年论文

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name

The histone variant macroH2A suppresses melanoma progression through regulation of CDK8.

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The histone variant macroH2A suppresses melanoma progression through regulation of CDK8.

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The histone variant macroH2A suppresses melanoma progression through regulation of CDK8.

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type

label

The histone variant macroH2A suppresses melanoma progression through regulation of CDK8.

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The histone variant macroH2A suppresses melanoma progression through regulation of CDK8.

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The histone variant macroH2A suppresses melanoma progression through regulation of CDK8.

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prefLabel

The histone variant macroH2A suppresses melanoma progression through regulation of CDK8.

@ast

The histone variant macroH2A suppresses melanoma progression through regulation of CDK8.

@en

The histone variant macroH2A suppresses melanoma progression through regulation of CDK8.

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The histone variant macroH2A suppresses melanoma progression through regulation of CDK8.

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Avnish Kapoor

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Benjamin A Garcia

http://www.w3.org/2001/XMLSchema#string

Chiara Vardabasso

http://www.w3.org/2001/XMLSchema#string

Claudia I Vidal

http://www.w3.org/2001/XMLSchema#string

David Polsky

http://www.w3.org/2001/XMLSchema#string

Emily Bernstein

http://www.w3.org/2001/XMLSchema#string

Eva Hernando

http://www.w3.org/2001/XMLSchema#string

Gary Leroy

http://www.w3.org/2001/XMLSchema#string

Iman Osman

http://www.w3.org/2001/XMLSchema#string

Kajan Ratnakumar

http://www.w3.org/2001/XMLSchema#string

P2860

The histone variant macroH2A1 marks repressed autosomal chromatin, but protects a subset of its target genes from silencing

The histone variant macroH2A is an epigenetic regulator of key developmental genes

Systematic and integrative analysis of large gene lists using DAVID bioinformatics resources

Mutations of the BRAF gene in human cancer

Histone macroH2A1 is concentrated in the inactive X chromosome of female mammals

CDK8 is a colorectal cancer oncogene that regulates beta-catenin activity

Formation of MacroH2A-containing senescence-associated heterochromatin foci and senescence driven by ASF1a and HIRA

MacroH2A, a core histone containing a large nonhistone region

Developmental and tissue expression patterns of histone macroH2A1 subtypes

Cancer statistics, 2009

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10.1038/NATURE09590

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3057940

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