Triggering cell death: the crystal structure of Apo2L/TRAIL in a complex with death receptor 5
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IL-17s adopt a cystine knot fold: structure and activity of a novel cytokine, IL-17F, and implications for receptor bindingModulation of the CD95-induced apoptosis: the role of CD95 N-glycosylationOnto better TRAILs for cancer treatmentPrinciples of antibody-mediated TNF receptor activationSubversion of cytokine networks by virally encoded decoy receptorsApoptotic agentsCrystal structure of TRAIL-DR5 complex identifies a critical role of the unique frame insertion in conferring recognition specificityCrystal structure of the TRANCE/RANKL cytokine reveals determinants of receptor-ligand specificityCrystal structure of the extracellular domain of mouse RANK ligand at 2.2-A resolutionStructural and functional analysis of the interaction between the agonistic monoclonal antibody Apomab and the proapoptotic receptor DR5Biochemical and Structural Characterization of the Human TL1A Ectodomain ,Structure-based development of a receptor activator of nuclear factor- B ligand (RANKL) inhibitor peptide and molecular basis for osteopetrosisCrystallographic and Mutational Analysis of the CD40-CD154 Complex and Its Implications for Receptor ActivationDecoy Strategies: The Structure of TL1A:DcR3 ComplexRANKL Employs Distinct Binding Modes to Engage RANK and the Osteoprotegerin Decoy ReceptorStructure of human cytomegalovirus UL141 binding to TRAIL-R2 reveals novel, non-canonical death receptor interactionsDimerization of LT R by LT 1 2 is necessary and sufficient for signal transductionRole of nanotechnology and gene delivery systems in TRAIL-based therapiesMolecular characterization of CD40 signaling intermediatesFollowing a TRAIL: update on a ligand and its five receptorsIdentification of a new murine tumor necrosis factor receptor locus that contains two novel murine receptors for tumor necrosis factor-related apoptosis-inducing ligand (TRAIL)Preparation of a functional fluorescent human Fas ligand extracellular domain derivative using a three-dimensional structure guided site-specific fluorochrome conjugationThe methionine-aromatic motif plays a unique role in stabilizing protein structure.The role of tumor necrosis factor receptor superfamily members in mammalian brain development, function and homeostasisRadiation-induced tumor neoantigens: imaging and therapeutic implications.Evolution of TNF-induced apoptosis reveals 550 My of functional conservation.The structure of the death receptor 4-TNF-related apoptosis-inducing ligand (DR4-TRAIL) complex.Protective effects of neurotrophic factors on tumor necrosis factor-related apoptosis-inducing ligand (TRAIL)-mediated apoptosis of murine adrenal chromaffin cell line tsAM5D.Possible novel therapy for malignant gliomas with secretable trimeric TRAIL.Human monomeric antibody fragments to TRAIL-R1 and TRAIL-R2 that display potent in vitro agonism.Synthetic constrained peptide selectively binds and antagonizes death receptor 5.Targeting a novel N-terminal epitope of death receptor 5 triggers tumor cell death.TNF alpha and the TNF receptor superfamily: structure-function relationship(s).The death domain kinase RIP is essential for TRAIL (Apo2L)-induced activation of IkappaB kinase and c-Jun N-terminal kinase.Preligand assembly domain-mediated ligand-independent association between TRAIL receptor 4 (TR4) and TR2 regulates TRAIL-induced apoptosisThe pre-ligand binding assembly domain: a potential target of inhibition of tumour necrosis factor receptor function.Identification and characterization of a novel agonistic anti-DR4 human monoclonal antibody.TRAIL and doxorubicin combination induces proapoptotic and antiangiogenic effects in soft tissue sarcoma in vivoStructural basis of LaDR5, a novel agonistic anti-death receptor 5 (DR5) monoclonal antibody, to inhibit DR5/TRAIL complex formationAdvances in Viral Vector-Based TRAIL Gene Therapy for Cancer.
P2860
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P2860
Triggering cell death: the crystal structure of Apo2L/TRAIL in a complex with death receptor 5
description
1999 nî lūn-bûn
@nan
1999 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած
@hyw
1999 թվականի հոտեմբերին հրատարակված գիտական հոդված
@hy
1999年の論文
@ja
1999年学术文章
@wuu
1999年学术文章
@zh-cn
1999年学术文章
@zh-hans
1999年学术文章
@zh-my
1999年学术文章
@zh-sg
1999年學術文章
@yue
name
Triggering cell death: the cry ...... complex with death receptor 5
@ast
Triggering cell death: the cry ...... complex with death receptor 5
@en
Triggering cell death: the cry ...... complex with death receptor 5
@en-gb
Triggering cell death: the cry ...... complex with death receptor 5
@nl
type
label
Triggering cell death: the cry ...... complex with death receptor 5
@ast
Triggering cell death: the cry ...... complex with death receptor 5
@en
Triggering cell death: the cry ...... complex with death receptor 5
@en-gb
Triggering cell death: the cry ...... complex with death receptor 5
@nl
prefLabel
Triggering cell death: the cry ...... complex with death receptor 5
@ast
Triggering cell death: the cry ...... complex with death receptor 5
@en
Triggering cell death: the cry ...... complex with death receptor 5
@en-gb
Triggering cell death: the cry ...... complex with death receptor 5
@nl
P2093
P921
P3181
P1433
P1476
Triggering cell death: the cry ...... complex with death receptor 5
@en
P2093
A Ashkenazi
A M de Vos
H W Christinger
M O'Connell
R F Kelley
S G Hymowitz
P304
P3181
P356
10.1016/S1097-2765(00)80207-5
P407
P577
1999-10-01T00:00:00Z