Haem-activated promiscuous targeting of artemisinin in Plasmodium falciparum - Wikidata - wikimedia - TriplyDB

Haem-activated promiscuous targeting of artemisinin in Plasmodium falciparum

Haem-activated promiscuous targeting of artemisinin in Plasmodium falciparum

http://www.wikidata.org/entity/Q22061870

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Artemisinin-based antimalarial research: application of biotechnology to the production of artemisinin, its mode of action, and the mechanism of resistance of Plasmodium parasites Recent advances in understanding apicomplexan parasites Genome-wide association analysis identifies genetic loci associated with resistance to multiple antimalarials in Plasmodium falciparum from China-Myanmar border Muddled mechanisms: recent progress towards antimalarial target identification Plasmodium falciparum: multifaceted resistance to artemisinins Recent advances in malaria genomics and epigenomics Chemical proteomics approaches for identifying the cellular targets of natural products Artemisinin Action and Resistance in Plasmodium falciparum PfCRT and PfMDR1 modulate interactions of artemisinin derivatives and ion channel blockers Artemisinins Target GABAA Receptor Signaling and Impair α Cell Identity The Essential Medicinal Chemistry of Curcumin The clinical impact of artemisinin resistance in Southeast Asia and the potential for future spread.Artemisinin resistance without pfkelch13 mutations in Plasmodium falciparum isolates from Cambodia.A tetraoxane-based antimalarial drug candidate that overcomes PfK13-C580Y dependent artemisinin resistance.Treatment of a chemoresistant neuroblastoma cell line with the antimalarial ozonide OZ513.H2O2 dynamics in the malaria parasite Plasmodium falciparum In situ Proteomic Profiling of Curcumin Targets in HCT116 Colon Cancer Cell Line.Ascorbic acid co-administration with artemisinin based combination therapies in falciparum malaria.Artemisinin-Resistant Plasmodium falciparum Malaria.Organism-like formation of Schistosoma hemozoin and its function suggest a mechanism for anti-malarial action of artemisinin.Quantitative chemical proteomics profiling of de novo protein synthesis during starvation-mediated autophagy.Problems and Solutions in Click Chemistry Applied to Drug Probes.The molecular and cellular action properties of artemisinins: what has yeast told us?A mitochondria-targeting artemisinin derivative with sharply increased antitumor but depressed anti-yeast and anti-malaria activities.The interaction of heme with plakortin and a synthetic endoperoxide analogue: new insights into the heme-activated antimalarial mechanism.Novel Plasmodium falciparum metabolic network reconstruction identifies shifts associated with clinical antimalarial resistance.QSAR based predictive modeling for anti-malarial molecules.Andrographolide Suppresses MV4-11 Cell Proliferation through the Inhibition of FLT3 Signaling, Fatty Acid Synthesis and Cellular Iron Uptake.Artesunate Activates the Intrinsic Apoptosis of HCT116 Cells through the Suppression of Fatty Acid Synthesis and the NF-κB Pathway.Knockout of the peroxiredoxin 5 homologue PFAOP does not affect the artemisinin susceptibility of Plasmodium falciparum.Artemisinin as an anticancer drug: Recent advances in target profiling and mechanisms of action.Immune suppressive properties of artemisinin family drugs.Application of proteomics in research on traditional Chinese medicine.Use of Integrated Computational Approaches in the Search for New Therapeutic Agents.A Click Chemistry-Based Proteomic Approach Reveals that 1,2,4-Trioxolane and Artemisinin Antimalarials Share a Common Protein Alkylation Profile.Oxidative stress in malaria and artemisinin combination therapy: Pros and Cons.Mechanistic Investigation of the Specific Anticancer Property of Artemisinin and Its Combination with Aminolevulinic Acid for Enhanced Anticolorectal Cancer Activity.Integrative approach for the analysis of the proteome-wide response to bismuth drugs in Helicobacter pylori.Bifunctional antimicrobial conjugates and hybrid antimicrobials.Comparison of the Exposure Time Dependence of the Activities of Synthetic Ozonide Antimalarials and Dihydroartemisinin against K13 Wild-Type and Mutant Plasmodium falciparum Strains.

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Haem-activated promiscuous targeting of artemisinin in Plasmodium falciparum

http://www.wikidata.org/entity/Q22061870

description

2015 nî lūn-bûn

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2015 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած

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2015 թվականի դեկտեմբերին հրատարակված գիտական հոդված

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2015年の論文

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2015年論文

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2015年論文

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2015年論文

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2015年論文

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2015年論文

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2015年论文

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name

Haem-activated promiscuous targeting of artemisinin in Plasmodium falciparum

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Haem-activated promiscuous targeting of artemisinin in Plasmodium falciparum

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Haem-activated promiscuous targeting of artemisinin in Plasmodium falciparum

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Haem-activated promiscuous targeting of artemisinin in Plasmodium falciparum

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Haem-activated promiscuous targeting of artemisinin in Plasmodium falciparum

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Haem-activated promiscuous targeting of artemisinin in Plasmodium falciparum

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Haem-activated promiscuous targeting of artemisinin in Plasmodium falciparum

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Haem-activated promiscuous targeting of artemisinin in Plasmodium falciparum

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Haem-activated promiscuous targeting of artemisinin in Plasmodium falciparum

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Haem-activated promiscuous targeting of artemisinin in Plasmodium falciparum

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Haem-activated promiscuous targeting of artemisinin in Plasmodium falciparum

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Haem-activated promiscuous targeting of artemisinin in Plasmodium falciparum

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Nature Communications

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Haem-activated promiscuous targeting of artemisinin in Plasmodium falciparum

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Bin Liu

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Cheryl C. Y. Loh

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Chin Xia Liew

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Jianbin Zhang

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Jigang Wang

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Kevin S. W. Tan

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Li-Xia Yuan

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Min Liu

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Nianci Lu

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Qingsong Lin

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Analysis of Plasmodium falciparum diversity in natural infections by deep sequencing

Recent clinical and molecular insights into emerging artemisinin resistance in Plasmodium falciparum

Spread of artemisinin resistance in Plasmodium falciparum malaria

Digestive-vacuole genesis and endocytic processes in the early intraerythrocytic stages of Plasmodium falciparum

Artemisinin Resistance in Plasmodium falciparum Malaria

A molecular marker of artemisinin-resistant Plasmodium falciparum malaria

Artemisinins target the SERCA of Plasmodium falciparum

A quantitative chemical proteomics approach to profile the specific cellular targets of andrographolide, a promising anticancer agent that suppresses tumor metastasis

Gene ontology: tool for the unification of biology

ClueGO: a Cytoscape plug-in to decipher functionally grouped gene ontology and pathway annotation networks

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10.1038/NCOMMS10111

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6

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Chong-Jing Zhang

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Plasmodium falciparum

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4703832

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