Phosphoprotein associated with glycosphingolipid-enriched microdomains (PAG), a novel ubiquitously expressed transmembrane adaptor protein, binds the protein tyrosine kinase csk and is involved in regulation of T cell activation
about
Systematic identification of regulatory proteins critical for T-cell activationStructural and functional dissection of the cytoplasmic domain of the transmembrane adaptor protein SIT (SHP2-interacting transmembrane adaptor protein)Coordinate interactions of Csk, Src, and Syk kinases with [alpha]IIb[beta]3 initiate integrin signaling to the cytoskeletonRegulation of FynT function by dual domain docking on PAG/CbpThe importance of three membrane-distal tyrosines in the adaptor protein NTAL/LABThe B cell-specific major raft protein, Raftlin, is necessary for the integrity of lipid raft and BCR signal transductionLyn, a Src family kinase, regulates activation of epidermal growth factor receptors in lung adenocarcinoma cellsNon-T cell activation linker (NTAL): a transmembrane adaptor protein involved in immunoreceptor signalingSCIMP, a transmembrane adaptor protein involved in major histocompatibility complex class II signalingDifferential role of glycolipid-enriched membrane domains in glycoprotein VI- and integrin-mediated phospholipase Cgamma2 regulation in plateletsPositive and negative regulation of T-cell activation through kinases and phosphatasesFunctional cooperation between c-Cbl and Src-like adaptor protein 2 in the negative regulation of T-cell receptor signaling.SH2 domain-mediated interaction of inhibitory protein tyrosine kinase Csk with protein tyrosine phosphatase-HSCFOccurrence of minimal change nephrotic syndrome in classical Hodgkin lymphoma is closely related to the induction of c-mip in Hodgkin-Reed Sternberg cells and podocytesLIME, a novel transmembrane adaptor protein, associates with p56lck and mediates T cell activationLIME: a new membrane Raft-associated adaptor protein involved in CD4 and CD8 coreceptor signalingMolecular Mechanisms for cAMP-Mediated Immunoregulation in T cells - Role of Anchored Protein Kinase A Signaling UnitsCo-operation of TLR4 and raft proteins in LPS-induced pro-inflammatory signalingProstaglandin E2 and T cells: friends or foes?Structure of the carboxyl-terminal Src kinase, CskProtein-tyrosine Phosphatase and Kinase Specificity in Regulation of SRC and Breast Tumor KinaseInteraction between two adapter proteins, PAG and EBP50: a possible link between membrane rafts and actin cytoskeletonCsk-binding protein (Cbp) negatively regulates epidermal growth factor-induced cell transformation by controlling Src activationKinome Screen Identifies PFKFB3 and Glucose Metabolism as Important Regulators of the Insulin/Insulin-like Growth Factor (IGF)-1 Signaling PathwayLck-dependent Fyn activation requires C terminus-dependent targeting of kinase-active Lck to lipid raftsProtein tyrosine phosphatases and the immune responseReciprocal regulation of lymphocyte activation by tyrosine kinases and phosphatasesThe adaptor protein EBP50 is important for localization of the protein kinase A-Ezrin complex in T-cells and the immunomodulating effect of cAMPPhosphorylation site dynamics of early T-cell receptor signalingCD45 ectodomain controls interaction with GEMs and Lck activity for optimal TCR signalingPhosphorylation-dependent regulation of T-cell activation by PAG/Cbp, a lipid raft-associated transmembrane adaptorThe Src family kinase Fgr is critical for activation of mast cells and IgE-mediated anaphylaxis in miceCo-recruitment analysis of the CBL and CBLB signalosomes in primary T cells identifies CD5 as a key regulator of TCR-induced ubiquitylationAn adaptor role for cytoplasmic Sam68 in modulating Src activity during cell polarization.Interactions between the Fyn SH3-domain and adaptor protein Cbp/PAG derived ligands, effects on kinase activity and affinity.A weak Lck tail bite is necessary for Lck function in T cell antigen receptor signaling.C-terminal Src kinase (CSK) and CSK-homologous kinase (CHK)--endogenous negative regulators of Src-family protein kinases.Removal of C-terminal SRC kinase from the immune synapse by a new binding proteinActivation of C-terminal Src kinase (Csk) by phosphorylation at serine-364 depends on the Csk-Src homology 3 domain.Structure-function analysis of Lyn kinase association with lipid rafts and initiation of early signaling events after Fcepsilon receptor I aggregation.
P2860
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P248
Q21245890-5E7F94E0-E53D-4D2A-9AE8-0F005C63F129Q24291394-7C07AC1C-220D-4196-BB60-229507436ACEQ24293554-6256E4E8-D608-4EB1-A562-38B345016A93Q24302122-BD0B857E-2B7B-4A5D-A98C-E07905D1CEEAQ24304913-13EECBE3-210C-46C7-9811-5E0881BF18C5Q24305079-BBF97663-7F38-4129-99B4-272158C76880Q24309725-55E61BBA-A14F-4417-8C98-37EB36D661F1Q24337208-F20924B9-4BE1-437C-A653-CCBBE161C4DCQ24338194-44B459C1-28AC-49E1-945F-5B507D6767BBQ24534153-C12D122D-A0E8-48FB-8310-83E8E46A14A3Q24535649-8001EF88-7335-45F3-8383-0D9B7527296AQ24537487-7B067F73-F34B-4C11-AC00-0A7313A8D412Q24548380-0BDD2B5F-8B83-47F4-87E5-673622A7904BQ24630620-9A455D4A-1DE9-4A62-8E8D-0BE9D0BD7EEAQ24672926-9143A517-3E8F-471E-8BFA-A5E9BD0D67F2Q24672962-978DACB3-ABDB-41C7-8349-458483020104Q26744973-23AA4264-4FD9-49AC-B990-5055B6CA06CEQ26866939-316334C1-1123-4933-9305-A5D4CFE14315Q27021151-EC93E673-709B-4ACA-82F6-84637E748E10Q27638251-54C7F767-1C31-4691-B6CA-6A2D23B2BE9CQ28116384-80008D72-4103-48FB-A717-64C25612FCE2Q28202663-10B5223A-36BD-4AE2-BD20-7B463115EAD0Q28236497-1BC94D27-E1DF-4157-A42E-0B1FAB256166Q28267012-306272F7-6290-4529-9DA5-187123505B31Q28288732-1C523223-4B88-4D5C-BBA7-5EEECE4EFC52Q28300971-5576B921-467D-446E-9B44-5371FB5541F5Q28344656-BA5680D7-22D5-484D-A1CB-368FF5C269CDQ28505451-03B77FFE-F57E-431D-B954-6188583D5146Q28542511-E0FE5BF7-F59E-47D8-8487-8F7A81A63440Q28567160-5DDB0A69-B111-4E11-9EDB-9BF20B5DDBFEQ28589506-A9A339FB-7EF1-41DF-8A40-7EBA76DB0C86Q28592326-CDB84E4E-2602-4426-B0FF-D24CC6473B8EQ28771482-EA67D625-C01A-4663-B06A-5FF8FA7F0FEDQ30157401-EAC58935-A38F-4A35-A15C-E5603D057ECAQ30157613-D8A080DB-BE4B-4C10-942D-A706CCFEAB51Q30157747-A07F3602-3000-49B6-B091-4EB0F9872483Q30160101-A1BA73B6-DD65-4FED-BD8F-2720969A83EDQ30160300-36C31901-3573-4099-BFC4-B263396B7CDAQ30164874-1146947C-B4E1-467B-9FE0-F0810665E051Q30167778-37C0237C-0A79-49A7-8CB9-BB837638C004
P2860
Phosphoprotein associated with glycosphingolipid-enriched microdomains (PAG), a novel ubiquitously expressed transmembrane adaptor protein, binds the protein tyrosine kinase csk and is involved in regulation of T cell activation
description
2000 nî lūn-bûn
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2000 թուականի Մայիսին հրատարակուած գիտական յօդուած
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2000 թվականի մայիսին հրատարակված գիտական հոդված
@hy
2000年の論文
@ja
2000年論文
@yue
2000年論文
@zh-hant
2000年論文
@zh-hk
2000年論文
@zh-mo
2000年論文
@zh-tw
2000年论文
@wuu
name
Phosphoprotein associated with ...... egulation of T cell activation
@ast
Phosphoprotein associated with ...... egulation of T cell activation
@en
Phosphoprotein associated with ...... egulation of T cell activation
@en-gb
Phosphoprotein associated with ...... egulation of T cell activation
@nl
type
label
Phosphoprotein associated with ...... egulation of T cell activation
@ast
Phosphoprotein associated with ...... egulation of T cell activation
@en
Phosphoprotein associated with ...... egulation of T cell activation
@en-gb
Phosphoprotein associated with ...... egulation of T cell activation
@nl
prefLabel
Phosphoprotein associated with ...... egulation of T cell activation
@ast
Phosphoprotein associated with ...... egulation of T cell activation
@en
Phosphoprotein associated with ...... egulation of T cell activation
@en-gb
Phosphoprotein associated with ...... egulation of T cell activation
@nl
P2093
P2860
P921
P3181
P356
P1476
Phosphoprotein associated with ...... egulation of T cell activation
@en
P2093
A Shevchenko
B Kornacker
B Schraven
D Pavlistová
P Angelisová
P2860
P304
P3181
P356
10.1084/JEM.191.9.1591
P407
P577
2000-05-01T00:00:00Z