A functional interaction of Ku with Werner exonuclease facilitates digestion of damaged DNA
about
p53 Modulates the exonuclease activity of Werner syndrome proteinIdentification and biochemical characterization of a Werner's syndrome protein complex with Ku70/80 and poly(ADP-ribose) polymerase-1Asymmetry of DNA replication fork progression in Werner's syndromeKu heterodimer binds to both ends of the Werner protein and functional interaction occurs at the Werner N-terminusUp-regulation of WRN and DNA ligase IIIalpha in chronic myeloid leukemia: consequences for the repair of DNA double-strand breaksRoles of Werner syndrome protein in protection of genome integrityModel of human aging: recent findings on Werner's and Hutchinson-Gilford progeria syndromesMycobacterial UvrD1 is a Ku-dependent DNA helicase that plays a role in multiple DNA repair events, including double-strand break repairRecQ helicases: caretakers of the genomeCoordinate action of the helicase and 3' to 5' exonuclease of Werner syndrome protein.Reconstitution of the mammalian DNA double-strand break end-joining reaction reveals a requirement for an Mre11/Rad50/NBS1-containing fraction.Nonhomologous end joining: a good solution for bad endsBCR/ABL modifies the kinetics and fidelity of DNA double-strand breaks repair in hematopoietic cells.Non-homologous end joining: emerging themes and unanswered questions.Functional interaction between DNA-PKcs and telomerase in telomere length maintenance.RECQ helicase RECQL4 participates in non-homologous end joining and interacts with the Ku complexRecQ helicases: suppressors of tumorigenesis and premature aging.Developing master keys to brain pathology, cancer and aging from the structural biology of proteins controlling reactive oxygen species and DNA repair.WRN exonuclease activity is blocked by DNA termini harboring 3' obstructive groups.Analysis of the Xenopus Werner syndrome protein in DNA double-strand break repair.Mechanisms of RecQ helicases in pathways of DNA metabolism and maintenance of genomic stabilityWRN Exonuclease activity is blocked by specific oxidatively induced base lesions positioned in either DNA strand.Werner syndrome protein, WRN, protects cells from DNA damage induced by the benzene metabolite hydroquinoneRecQ helicases; at the crossroad of genome replication, repair, and recombination.Resolution of complex ends by Nonhomologous end joining - better to be lucky than good?Bloom's syndrome: Why not premature aging?: A comparison of the BLM and WRN helicases.BCR/ABL stimulates WRN to promote survival and genomic instability.WRN protein and Werner syndrome.The Ku-binding motif is a conserved module for recruitment and stimulation of non-homologous end-joining proteins.DNA damage-induced translocation of the Werner helicase is regulated by acetylation.Werner and Bloom helicases are involved in DNA repair in a complementary fashion.Depletion of Werner helicase results in mitotic hyperrecombination and pleiotropic homologous and nonhomologous recombination phenotypes.Biochemical characterization of an exonuclease from Arabidopsis thaliana reveals similarities to the DNA exonuclease of the human Werner syndrome protein.DNA repair and the origins of urinary oxidized 2'-deoxyribonucleosides.Effect of bulky lesions on DNA: solution structure of a DNA duplex containing a cholesterol adduct.In vivo prooxidant state in Werner syndrome (WS): results from three WS patients and two WS heterozygotes.Werner syndrome protein, the MRE11 complex and ATR: menage-à-trois in guarding genome stability during DNA replication?The Werner syndrome protein is required for recruitment of chromatin assembly factor 1 following DNA damage.
P2860
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P2860
A functional interaction of Ku with Werner exonuclease facilitates digestion of damaged DNA
description
2001 nî lūn-bûn
@nan
2001 թուականի Մայիսին հրատարակուած գիտական յօդուած
@hyw
2001 թվականի մայիսին հրատարակված գիտական հոդված
@hy
2001年の論文
@ja
2001年学术文章
@wuu
2001年学术文章
@zh-cn
2001年学术文章
@zh-hans
2001年学术文章
@zh-my
2001年学术文章
@zh-sg
2001年學術文章
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name
A functional interaction of Ku ...... tates digestion of damaged DNA
@ast
A functional interaction of Ku ...... tates digestion of damaged DNA
@en
A functional interaction of Ku ...... tates digestion of damaged DNA
@en-gb
A functional interaction of Ku ...... tates digestion of damaged DNA
@nl
type
label
A functional interaction of Ku ...... tates digestion of damaged DNA
@ast
A functional interaction of Ku ...... tates digestion of damaged DNA
@en
A functional interaction of Ku ...... tates digestion of damaged DNA
@en-gb
A functional interaction of Ku ...... tates digestion of damaged DNA
@nl
prefLabel
A functional interaction of Ku ...... tates digestion of damaged DNA
@ast
A functional interaction of Ku ...... tates digestion of damaged DNA
@en
A functional interaction of Ku ...... tates digestion of damaged DNA
@en-gb
A functional interaction of Ku ...... tates digestion of damaged DNA
@nl
P2093
P2860
P3181
P356
P1476
A functional interaction of Ku ...... tates digestion of damaged DNA
@en
P2093
P2860
P304
P3181
P356
10.1093/NAR/29.9.1926
P407
P577
2001-05-01T00:00:00Z