Tcf4 can specifically recognize beta-catenin using alternative conformations
about
Fuzziness: linking regulation to protein dynamicsClassification of intrinsically disordered regions and proteinsThermodynamics of beta-catenin-ligand interactions: the roles of the N- and C-terminal tails in modulating binding affinityThe RNA aptamer disrupts protein-protein interaction between beta-catenin and nuclear factor-kappaB p50 and regulates the expression of C-reactive proteinCrystal structure of a beta-catenin/axin complex suggests a mechanism for the beta-catenin destruction complexThe Wnt-dependent signaling pathways as target in oncology drug discoveryFuzzy complexes: Specific binding without complete foldingThe G protein α chaperone Ric-8 as a potential therapeutic targetCell-context dependent TCF/LEF expression and function: alternative tales of repression, de-repression and activation potentialsThe C. elegans SYS-1 Protein Is a Bona Fide β-CateninBiochemical and Structural Characterization of β-Catenin Interactions with Nonphosphorylated and CK2-Phosphorylated Lef-1Structural basis of coactivation of liver receptor homolog-1 by -cateninAcetylation of beta-catenin by p300 regulates beta-catenin-Tcf4 interactionStructural characterization of partially disordered human Chibby: insights into its function in the Wnt-signaling pathwayDrug development against metastasis-related genes and their pathways: A rationale for cancer therapyResonance assignment of disordered protein with repetitive and overlapping sequence using combinatorial approach reveals initial structural propensities and local restrictions in the denatured state.A small molecule inhibitor of beta-catenin/CREB-binding protein transcription [corrected]Wingless signalling alters the levels, subcellular distribution and dynamics of Armadillo and E-cadherin in third instar larval wing imaginal discs.Molecular docking studies of flavonoids for their inhibition pattern against β-catenin and pharmacophore model generation from experimentally known flavonoids to fabricate more potent inhibitors for Wnt signaling pathwayThe 19-amino acid insertion in the tumor-associated splice isoform Rac1b confers specific binding to p120 catenin.The evolutionary origin of epithelial cell-cell adhesion mechanismsThe melanoma tumor antigen, melanotransferrin (p97): a 25-year hallmark--from iron metabolism to tumorigenesis.T-cell factors: turn-ons and turn-offsT-cell factor 4 functions as a tumor suppressor whose disruption modulates colon cell proliferation and tumorigenesis.The β-catenin/Tcf4/survivin signaling maintains a less differentiated phenotype and high proliferative capacity of human corneal epithelial progenitor cells.Purification, crystallization and preliminary X-ray diffraction studies of the β-catenin homolog HMP-2 from Caenorhabditis elegans.Wnt-β-catenin-Tcf-4 signalling-modulated invasiveness is dependent on osteopontin expression in breast cancer.Distinct and mutually inhibitory binding by two divergent β-catenins coordinates TCF levels and activity in C. elegans.Functional inhibition of β-catenin-mediated Wnt signaling by intracellular VHH antibodiesFunction of Wnt/β-catenin in counteracting Tcf3 repression through the Tcf3-β-catenin interactionβ-Catenin recognizes a specific RNA motif in the cyclooxygenase-2 mRNA 3'-UTR and interacts with HuR in colon cancer cellsInhibition of β-catenin-TCF1 interaction delays differentiation of mouse embryonic stem cells.Molecular plasticity of beta-catenin: new insights from single-molecule measurements and MD simulation.Diversity of LEF/TCF action in development and disease.Gene expression and pathway analysis of CTNNB1 in cancer and stem cells.Critical pathways in heart function: bis(2-chloroethoxy)methane-induced heart gene transcript change in F344 rats.The role of β-catenin in the initiation and metastasis of TA2 mice spontaneous breast cancer.Endothelial NO Synthase-Dependent S-Nitrosylation of β-Catenin Prevents Its Association with TCF4 and Inhibits Proliferation of Endothelial Cells Stimulated by Wnt3a.Hox functional diversity: Novel insights from flexible motif folding and plastic protein interaction.Aberrant expression and function of TCF4 in the proliferation of hepatocellular carcinoma cell line BEL-7402.
P2860
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P2860
Tcf4 can specifically recognize beta-catenin using alternative conformations
description
2001 nî lūn-bûn
@nan
2001 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2001 թվականի դեկտեմբերին հրատարակված գիտական հոդված
@hy
2001年の論文
@ja
2001年学术文章
@wuu
2001年学术文章
@zh-cn
2001年学术文章
@zh-hans
2001年学术文章
@zh-my
2001年学术文章
@zh-sg
2001年學術文章
@yue
name
Tcf4 can specifically recognize beta-catenin using alternative conformations
@ast
Tcf4 can specifically recognize beta-catenin using alternative conformations
@en
Tcf4 can specifically recognize beta-catenin using alternative conformations
@en-gb
Tcf4 can specifically recognize beta-catenin using alternative conformations
@nl
type
label
Tcf4 can specifically recognize beta-catenin using alternative conformations
@ast
Tcf4 can specifically recognize beta-catenin using alternative conformations
@en
Tcf4 can specifically recognize beta-catenin using alternative conformations
@en-gb
Tcf4 can specifically recognize beta-catenin using alternative conformations
@nl
prefLabel
Tcf4 can specifically recognize beta-catenin using alternative conformations
@ast
Tcf4 can specifically recognize beta-catenin using alternative conformations
@en
Tcf4 can specifically recognize beta-catenin using alternative conformations
@en-gb
Tcf4 can specifically recognize beta-catenin using alternative conformations
@nl
P2093
P356
P1476
Tcf4 can specifically recognize beta-catenin using alternative conformations
@en
P2093
P304
P356
10.1038/NSB718
P407
P50
P577
2001-12-01T00:00:00Z