The 19-amino acid insertion in the tumor-associated splice isoform Rac1b confers specific binding to p120 catenin.
about
The Rac1 splice form Rac1b promotes K-ras-induced lung tumorigenesisMatrix metalloproteinase induction of Rac1b, a key effector of lung cancer progressionRACK1, A multifaceted scaffolding protein: Structure and function.PTP-PEST targets a novel tyrosine site in p120 catenin to control epithelial cell motility and Rho GTPase activity.Tumor cell-derived MMP3 orchestrates Rac1b and tissue alterations that promote pancreatic adenocarcinoma.Matrix metalloproteinases as breast cancer drivers and therapeutic targets.Matrix compliance regulates Rac1b localization, NADPH oxidase assembly, and epithelial-mesenchymal transition.Tumor cell expression of MMP3 as a prognostic factor for poor survival in pancreatic, pulmonary, and mammary carcinomaUpon Wnt stimulation, Rac1 activation requires Rac1 and Vav2 binding to p120-catenin.Involvement of hnRNP A1 in the matrix metalloprotease-3-dependent regulation of Rac1 pre-mRNA splicing.p120 catenin: an essential regulator of cadherin stability, adhesion-induced signaling, and cancer progression.The importance of matrix metalloproteinase-3 in respiratory disorders.Rac1b negatively regulates TGF-β1-induced cell motility in pancreatic ductal epithelial cells by suppressing Smad signallingRac1b enhances cell survival through activation of the JNK2/c-JUN/Cyclin-D1 and AKT2/MCL1 pathways.EMT and stemness: flexible processes tuned by alternative splicing in development and cancer progression.Insufficient ability of Rac1b to perturb cystogenesis.Cadherins function during the collective cell migration of Xenopus Cranial Neural Crest cells: revisiting the role of E-cadherin.RACK1 regulates VEGF/Flt1-mediated cell migration via activation of a PI3K/Akt pathway.Therapeutic Potential of Matrix Metalloproteinase Inhibition in Breast Cancer.Regulation of epithelial-mesenchymal transition in breast cancer cells by cell contact and adhesion.Ovarian Tumor Microenvironment Signaling: Convergence on the Rac1 GTPase
P2860
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P2860
The 19-amino acid insertion in the tumor-associated splice isoform Rac1b confers specific binding to p120 catenin.
description
2010 nî lūn-bûn
@nan
2010 թուականի Ապրիլին հրատարակուած գիտական յօդուած
@hyw
2010 թվականի ապրիլին հրատարակված գիտական հոդված
@hy
2010年の論文
@ja
2010年論文
@yue
2010年論文
@zh-hant
2010年論文
@zh-hk
2010年論文
@zh-mo
2010年論文
@zh-tw
2010年论文
@wuu
name
The 19-amino acid insertion in ...... cific binding to p120 catenin.
@ast
The 19-amino acid insertion in ...... cific binding to p120 catenin.
@en
type
label
The 19-amino acid insertion in ...... cific binding to p120 catenin.
@ast
The 19-amino acid insertion in ...... cific binding to p120 catenin.
@en
prefLabel
The 19-amino acid insertion in ...... cific binding to p120 catenin.
@ast
The 19-amino acid insertion in ...... cific binding to p120 catenin.
@en
P2093
P2860
P356
P1476
The 19-amino acid insertion in ...... cific binding to p120 catenin.
@en
P2093
Davitte Khauv
Derek C Radisky
Evette S Radisky
Lidiya Orlichenko
Masahiro Yanagisawa
Panos Z Anastasiadis
Rory Geyer
P2860
P304
19153-19161
P356
10.1074/JBC.M109.099382
P407
P577
2010-04-15T00:00:00Z