BRCA1-induced large-scale chromatin unfolding and allele-specific effects of cancer-predisposing mutations.
about
Centrosome-associated regulators of the G(2)/M checkpoint as targets for cancer therapyInteraction between BRCA2 and replication protein A is compromised by a cancer-predisposing mutation in BRCA2Human transcription elongation factor NELF: identification of novel subunits and reconstitution of the functionally active complexBRCA1 interacts with FHL2 and enhances FHL2 transactivation functionRoles of BRCA1 in centrosome duplicationPotentiation of Smad-mediated transcriptional activation by the RNA-binding protein RBPMSBRCA1 cooperates with NUFIP and P-TEFb to activate transcription by RNA polymerase IIAttenuation of estrogen receptor alpha-mediated transcription through estrogen-stimulated recruitment of a negative elongation factor.Chromatin decondensation and nuclear reorganization of the HoxB locus upon induction of transcriptionAssociation of BRCA1 with the inactive X chromosome and XIST RNALigand-independent activation of estrogen receptor alpha by XBP-1Ligand-specific dynamics of the androgen receptor at its response element in living cellsRegulation of BRCA1 expression and its relationship to sporadic breast cancerThe architecture of chicken chromosome territories changes during differentiationAn hGCN5/TRRAP histone acetyltransferase complex co-activates BRCA1 transactivation function through histone modificationEnhancement of BRCA1 E3 ubiquitin ligase activity through direct interaction with the BARD1 proteinBRCA1 phosphorylation by Aurora-A in the regulation of G2 to M transitionFunctional impact of missense variants in BRCA1 predicted by supervised learningMouse cofactor of BRCA1 (Cobra1) is required for early embryogenesis.Inhibition of histone deacetylase impacts cancer stem cells and induces epithelial-mesenchyme transition of head and neck cancerPhosphorylated BRCA1 is predominantly located in the nucleus and mitochondriaCdc6 chromatin affinity is unaffected by serine-54 phosphorylation, S-phase progression, and overexpression of cyclin A.Chromatin unfolding by Cdt1 regulates MCM loading via opposing functions of HBO1 and HDAC11-geminin.Chromatin decondensation in S-phase involves recruitment of Cdk2 by Cdc45 and histone H1 phosphorylationCofactor of BRCA1 modulates androgen-dependent transcription and alternative splicing.Concerted transcriptional regulation by BRCA1 and COBRA1 in breast cancer cellsGeneric features of tertiary chromatin structure as detected in natural chromosomes.Yeast screens identify the RNA polymerase II CTD and SPT5 as relevant targets of BRCA1 interaction.Common effects of acidic activators on large-scale chromatin structure and transcription.Attenuation of RNA polymerase II pausing mitigates BRCA1-associated R-loop accumulation and tumorigenesis.The fractal globule as a model of chromatin architecture in the cellA new non-catalytic role for ubiquitin ligase RNF8 in unfolding higher-order chromatin structure.Alteration of large-scale chromatin structure by estrogen receptorRole of BRCA1 and BRCA2 as regulators of DNA repair, transcription, and cell cycle in response to DNA damage.The WSTF-ISWI chromatin remodeling complex transiently associates with the human inactive X chromosome during late S-phase prior to BRCA1 and γ-H2AXPol II waiting in the starting gates: Regulating the transition from transcription initiation into productive elongation.Genetic predisposition directs breast cancer phenotype by dictating progenitor cell fate.Hepatitis B virus X protein and the estrogen receptor variant lacking exon 5 inhibit estrogen receptor signaling in hepatoma cellsChromosome and gene alterations in breast cancer as markers for diagnosis and prognosis as well as pathogenetic targets for therapy.Aberrant recombination and repair during immunoglobulin class switching in BRCA1-deficient human B cells
P2860
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P2860
BRCA1-induced large-scale chromatin unfolding and allele-specific effects of cancer-predisposing mutations.
description
2001 nî lūn-bûn
@nan
2001 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2001 թվականի դեկտեմբերին հրատարակված գիտական հոդված
@hy
2001年の論文
@ja
2001年学术文章
@wuu
2001年学术文章
@zh-cn
2001年学术文章
@zh-hans
2001年学术文章
@zh-my
2001年学术文章
@zh-sg
2001年學術文章
@yue
name
BRCA1-induced large-scale chro ...... cancer-predisposing mutations
@nl
BRCA1-induced large-scale chro ...... cancer-predisposing mutations.
@ast
BRCA1-induced large-scale chro ...... cancer-predisposing mutations.
@en
BRCA1-induced large-scale chro ...... cancer-predisposing mutations.
@en-gb
type
label
BRCA1-induced large-scale chro ...... cancer-predisposing mutations
@nl
BRCA1-induced large-scale chro ...... cancer-predisposing mutations.
@ast
BRCA1-induced large-scale chro ...... cancer-predisposing mutations.
@en
BRCA1-induced large-scale chro ...... cancer-predisposing mutations.
@en-gb
prefLabel
BRCA1-induced large-scale chro ...... cancer-predisposing mutations
@nl
BRCA1-induced large-scale chro ...... cancer-predisposing mutations.
@ast
BRCA1-induced large-scale chro ...... cancer-predisposing mutations.
@en
BRCA1-induced large-scale chro ...... cancer-predisposing mutations.
@en-gb
P2093
P2860
P356
P1476
BRCA1-induced large-scale chro ...... cancer-predisposing mutations.
@en
P2093
P2860
P304
P356
10.1083/JCB.200108049
P407
P577
2001-12-10T00:00:00Z