Characterization of a carboxy-terminal BRCA1 interacting protein
about
Nuclear localization and cell cycle-specific expression of CtIP, a protein that associates with the BRCA1 tumor suppressorFunctional link of BRCA1 and ataxia telangiectasia gene product in DNA damage responseBRCA1-induced large-scale chromatin unfolding and allele-specific effects of cancer-predisposing mutations.The LIM domain protein LMO4 interacts with the cofactor CtIP and the tumor suppressor BRCA1 and inhibits BRCA1 activityDNA damage-induced cell cycle checkpoint control requires CtIP, a phosphorylation-dependent binding partner of BRCA1 C-terminal domainsHighlight: BRCA1 and BRCA2 proteins in breast cancerCCDC98 targets BRCA1 to DNA damage sitesHuman CtIP promotes DNA end resectionZEB represses transcription through interaction with the corepressor CtBPCBP/p300 interact with and function as transcriptional coactivators of BRCA1BRCA1 interacts with components of the histone deacetylase complexUse of adenoviral E1A protein to analyze K18 promoter deregulation in colon carcinoma cells discloses a role for CtBP1 and BRCA1.DNA End Resection: Facts and MechanismsMolecular mechanisms of etoposide53BP1 regulates DSB repair using Rif1 to control 5' end resectionHomologous recombination and human health: the roles of BRCA1, BRCA2, and associated proteinsHuman CtIP mediates cell cycle control of DNA end resection and double strand break repairIdentification of proteins that interact with BRCA1 by Far-Western library screeningThe CtBP family: enigmatic and enzymatic transcriptional co-repressorsAdenosine nucleotide modulates the physical interaction between hMSH2 and BRCA1Redistribution of BRCA1 among four different protein complexes following replication blockageNFBD1, a novel nuclear protein with signature motifs of FHA and BRCT, and an internal 41-amino acid repeat sequence, is an early participant in DNA damage responseBRCA1 and Oxidative StressInactivation of CtIP leads to early embryonic lethality mediated by G1 restraint and to tumorigenesis by haploid insufficiencyA functional comparison of BRCA1 C-terminal domains in transcription activation and chromatin remodeling.Dimerization of CtIP, a BRCA1- and CtBP-interacting protein, is mediated by an N-terminal coiled-coil motif.The ubiquitin system, disease, and drug discovery.CtIP-mediated resection is essential for viability and can operate independently of BRCA1.Emerging roles of BRCA1 in transcriptional regulation and DNA repair.Taking a Bad Turn: Compromised DNA Damage Response in LeukemiaBRCA1 and cell signaling.Lessons learned from BRCA1 and BRCA2.Akt: a double-edged sword in cell proliferation and genome stability.Contribution of DEAF1 structural domains to the interaction with the breast cancer oncogene LMO4.Loss of BRCA1-A complex function in RAP80 null tumor cellsBRCA1, PARP, and 53BP1: conditional synthetic lethality and synthetic viability.BRCA1 haploinsufficiency for replication stress suppression in primary cellsRAP80-directed tuning of BRCA1 homologous recombination function at ionizing radiation-induced nuclear foci.BRCA1 ubiquitinates its phosphorylation-dependent binding partner CtIPThe breast cancer susceptibility genes (BRCA) in breast and ovarian cancers.
P2860
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P2860
Characterization of a carboxy-terminal BRCA1 interacting protein
description
1998 nî lūn-bûn
@nan
1998 թուականի Նոյեմբերին հրատարակուած գիտական յօդուած
@hyw
1998 թվականի նոյեմբերին հրատարակված գիտական հոդված
@hy
1998年の論文
@ja
1998年論文
@yue
1998年論文
@zh-hant
1998年論文
@zh-hk
1998年論文
@zh-mo
1998年論文
@zh-tw
1998年论文
@wuu
name
Characterization of a carboxy-terminal BRCA1 interacting protein
@ast
Characterization of a carboxy-terminal BRCA1 interacting protein
@en
Characterization of a carboxy-terminal BRCA1 interacting protein
@en-gb
Characterization of a carboxy-terminal BRCA1 interacting protein
@nl
type
label
Characterization of a carboxy-terminal BRCA1 interacting protein
@ast
Characterization of a carboxy-terminal BRCA1 interacting protein
@en
Characterization of a carboxy-terminal BRCA1 interacting protein
@en-gb
Characterization of a carboxy-terminal BRCA1 interacting protein
@nl
prefLabel
Characterization of a carboxy-terminal BRCA1 interacting protein
@ast
Characterization of a carboxy-terminal BRCA1 interacting protein
@en
Characterization of a carboxy-terminal BRCA1 interacting protein
@en-gb
Characterization of a carboxy-terminal BRCA1 interacting protein
@nl
P2093
P3181
P356
P1433
P1476
Characterization of a carboxy-terminal BRCA1 interacting protein
@en
P2093
P A Ormonde
P Dayananth
P L Bartel
Q Lawrence
P2888
P304
P3181
P356
10.1038/SJ.ONC.1202150
P407
P577
1998-11-05T00:00:00Z
P5875
P6179
1029822114