Cloning and characterization of a novel mammalian zinc transporter, zinc transporter 5, abundantly expressed in pancreatic beta cells
about
In silico identification and expression of SLC30 family genes: an expressed sequence tag data mining strategy for the characterization of zinc transporters' tissue expressionZinc transporter 2 (SLC30A2) can suppress the vesicular zinc defect of adaptor protein 3-depleted fibroblasts by promoting zinc accumulation in lysosomesThe zinc transporter ZnT3 interacts with AP-3 and it is preferentially targeted to a distinct synaptic vesicle subpopulationThe cation efflux transporter ZnT8 (Slc30A8) is a major autoantigen in human type 1 diabetesZinc as Allosteric Ion Channel Modulator: Ionotropic Receptors as MetalloproteinsZinc and the Msc2 zinc transporter protein are required for endoplasmic reticulum function.Heteromeric protein complexes mediate zinc transport into the secretory pathway of eukaryotic cells.Structure, function, and regulation of a subfamily of mouse zinc transporter genesInsulin storage and glucose homeostasis in mice null for the granule zinc transporter ZnT8 and studies of the type 2 diabetes-associated variantsZinc and zinc transporter regulation in pancreatic islets and the potential role of zinc in islet transplantationCompound heterozygous mutations in SLC30A2/ZnT2 results in low milk zinc concentrations: a novel mechanism for zinc deficiency in a breast-fed infantDown-regulation of ZnT8 expression in INS-1 rat pancreatic beta cells reduces insulin content and glucose-inducible insulin secretionIntracellular distribution of labile Zn(II) and zinc transporter expression in kidney and MDCK cellsEfflux-mediated heavy metal resistance in prokaryotes.Behavioral impairments in animal models for zinc deficiency.SLC30A3 responds to glucose- and zinc variations in beta-cells and is critical for insulin production and in vivo glucose-metabolism during beta-cell stress.Zinc transporters and their role in the pancreatic β-cell.X-ray fluorescence microscopy reveals accumulation and secretion of discrete intracellular zinc pools in the lactating mouse mammary gland.Differential subcellular localization of the splice variants of the zinc transporter ZnT5 is dictated by the different C-terminal regionsMeeting of the minds: metalloneurochemistryExpression of the zinc transporter ZnT4 is decreased in the progression from early prostate disease to invasive prostate cancer.Lysosome-related organelles as mediators of metal homeostasis.The ZIP7 gene (Slc39a7) encodes a zinc transporter involved in zinc homeostasis of the Golgi apparatus.Decreased intracellular zinc in human tumorigenic prostate epithelial cells: a possible role in prostate cancer progressionPhylogenetic and functional analysis of the Cation Diffusion Facilitator (CDF) family: improved signature and prediction of substrate specificity.Intracellular zinc homeostasis in leukocyte subsets is regulated by different expression of zinc exporters ZnT-1 to ZnT-9.Zinc in specialized secretory tissues: roles in the pancreas, prostate, and mammary gland.Effects of zinc supplementation and zinc chelation on in vitro β-cell function in INS-1E cells.Glucose regulates free cytosolic Zn²⁺ concentration, Slc39 (ZiP), and metallothionein gene expression in primary pancreatic islet β-cellsTranscriptome response to heavy metal stress in Drosophila reveals a new zinc transporter that confers resistance to zincA global view of the selectivity of zinc deprivation and excess on genes expressed in human THP-1 mononuclear cells.Cucumber metal transport protein MTP8 confers increased tolerance to manganese when expressed in yeast and Arabidopsis thalianaHomeostatic regulation of zinc transporters in the human small intestine by dietary zinc supplementation.Intestinal and placental zinc transport pathways.Histidine pairing at the metal transport site of mammalian ZnT transporters controls Zn2+ over Cd2+ selectivity.Altered expression of two zinc transporters, SLC30A5 and SLC30A6, underlies a mammary gland disorder of reduced zinc secretion into milkIslet autoantigens: structure, function, localization, and regulation.The Znt4 mutation inlethal milk mice affects intestinal zinc homeostasis through the expression of other Zn transportersZnt7-null mice are more susceptible to diet-induced glucose intolerance and insulin resistance.Identification of the human zinc transcriptional regulatory element (ZTRE): a palindromic protein-binding DNA sequence responsible for zinc-induced transcriptional repression.
P2860
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P2860
Cloning and characterization of a novel mammalian zinc transporter, zinc transporter 5, abundantly expressed in pancreatic beta cells
description
2002 nî lūn-bûn
@nan
2002 թուականի Մայիսին հրատարակուած գիտական յօդուած
@hyw
2002 թվականի մայիսին հրատարակված գիտական հոդված
@hy
2002年の論文
@ja
2002年論文
@yue
2002年論文
@zh-hant
2002年論文
@zh-hk
2002年論文
@zh-mo
2002年論文
@zh-tw
2002年论文
@wuu
name
Cloning and characterization o ...... essed in pancreatic beta cells
@ast
Cloning and characterization o ...... essed in pancreatic beta cells
@en
Cloning and characterization o ...... essed in pancreatic beta cells
@en-gb
Cloning and characterization o ...... essed in pancreatic beta cells
@nl
type
label
Cloning and characterization o ...... essed in pancreatic beta cells
@ast
Cloning and characterization o ...... essed in pancreatic beta cells
@en
Cloning and characterization o ...... essed in pancreatic beta cells
@en-gb
Cloning and characterization o ...... essed in pancreatic beta cells
@nl
prefLabel
Cloning and characterization o ...... essed in pancreatic beta cells
@ast
Cloning and characterization o ...... essed in pancreatic beta cells
@en
Cloning and characterization o ...... essed in pancreatic beta cells
@en-gb
Cloning and characterization o ...... essed in pancreatic beta cells
@nl
P2093
P2860
P3181
P356
P1476
Cloning and characterization o ...... essed in pancreatic beta cells
@en
P2093
Hiroshi Narita
Junko Hirose
Koshi Mori
Masaya Nagao
Naomi Sugiura
Ryuzo Sasaki
Taiho Kambe
Tatsuaki Amano
Toshihiko Iwanaga
Yuko Yamaguchi-Iwai
P2860
P304
P3181
P356
10.1074/JBC.M200910200
P407
P577
2002-05-24T00:00:00Z