SKAP55 coupled with CD45 positively regulates T-cell receptor-mediated gene transcription
about
An essential role for SKAP-55 in LFA-1 clustering on T cells that cannot be substituted by SKAP-55RSKAP55 recruits to lipid rafts and positively mediates the MAPK pathway upon T cell receptor activationPTEN associates with the vault particles in HeLa cellsDeficiency of ADAP/Fyb/SLAP-130 destabilizes SKAP55 in Jurkat T cellsThe N terminus of SKAP55 enables T cell adhesion to TCR and integrin ligands via distinct mechanisms.Adaptor SKAP-55 binds p21 activating exchange factor RasGRP1 and negatively regulates the p21-ERK pathway in T-cells.CD45, CD148, and Lyp/Pep: critical phosphatases regulating Src family kinase signaling networks in immune cellsThe TCR ADAPts to integrin-mediated cell adhesion.CD45: all is not yet crystal clear.LFA-1-mediated T cell costimulation through increased localization of TCR/class II complexes to the central supramolecular activation cluster and exclusion of CD45 from the immunological synapseFunctional defects of SKAP-55-deficient T cells identify a regulatory role for the adaptor in LFA-1 adhesionRegulation of in vitro and in vivo immune functions by the cytosolic adaptor protein SKAP-HOM.
P2860
Q24646010-6AC1663A-FA12-40DA-BE9B-EDC29A1EDF04Q28217325-D58DED50-8733-4105-95EC-748DD37E48C5Q28217868-9AE50D23-155A-4557-BA6A-7314A7BCCDBDQ28246643-11066C6A-E8B9-4373-B73E-A6D0687F339CQ30009507-8D0B3F99-F458-44C9-B440-F1C330B1BEDCQ33322525-697EB17F-44B9-4E3A-9B17-0B817252BD0DQ34963679-09216E96-961D-49AD-A599-8FAF4F27F71EQ35096688-7F990137-C88F-484A-BA6A-05A4546D727BQ36372544-C96B4BEE-4D42-4DC6-B228-95FAEF54DB59Q37712605-D0B6763B-CBAC-4022-8AD1-48A935B4A2FAQ40804411-92F22AA0-8955-4888-92BD-D9E3FCF71FBDQ42537490-EDB54B80-1478-425A-97E5-4974DAB19388
P2860
SKAP55 coupled with CD45 positively regulates T-cell receptor-mediated gene transcription
description
2002 nî lūn-bûn
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2002 թուականի Ապրիլին հրատարակուած գիտական յօդուած
@hyw
2002 թվականի ապրիլին հրատարակված գիտական հոդված
@hy
2002年の論文
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2002年論文
@yue
2002年論文
@zh-hant
2002年論文
@zh-hk
2002年論文
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2002年論文
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2002年论文
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name
SKAP55 coupled with CD45 positively regulates T-cell receptor-mediated gene transcription
@ast
SKAP55 coupled with CD45 positively regulates T-cell receptor-mediated gene transcription
@en
SKAP55 coupled with CD45 positively regulates T-cell receptor-mediated gene transcription
@en-gb
SKAP55 coupled with CD45 positively regulates T-cell receptor-mediated gene transcription
@nl
type
label
SKAP55 coupled with CD45 positively regulates T-cell receptor-mediated gene transcription
@ast
SKAP55 coupled with CD45 positively regulates T-cell receptor-mediated gene transcription
@en
SKAP55 coupled with CD45 positively regulates T-cell receptor-mediated gene transcription
@en-gb
SKAP55 coupled with CD45 positively regulates T-cell receptor-mediated gene transcription
@nl
prefLabel
SKAP55 coupled with CD45 positively regulates T-cell receptor-mediated gene transcription
@ast
SKAP55 coupled with CD45 positively regulates T-cell receptor-mediated gene transcription
@en
SKAP55 coupled with CD45 positively regulates T-cell receptor-mediated gene transcription
@en-gb
SKAP55 coupled with CD45 positively regulates T-cell receptor-mediated gene transcription
@nl
P2093
P2860
P921
P1476
SKAP55 coupled with CD45 positively regulates T-cell receptor-mediated gene transcription
@en
P2093
Liangtang Wu
Shi-Hsiang Shen
P2860
P304
P356
10.1128/MCB.22.8.2673-2686.2002
P407
P577
2002-04-01T00:00:00Z