Menin is required for bone morphogenetic protein 2- and transforming growth factor beta-regulated osteoblastic differentiation through interaction with Smads and Runx2
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Menin suppresses osteoblast differentiation by antagonizing the AP-1 factor, JunDInherited pancreatic endocrine tumor syndromes: advances in molecular pathogenesis, diagnosis, management, and controversiesConditional expression of Smad7 in pancreatic beta cells disrupts TGF-beta signaling and induces reversible diabetes mellitusTGF-β/BMP signaling and other molecular events: regulation of osteoblastogenesis and bone formationMultiple endocrine neoplasia type 1 (MEN1) and type 4 (MEN4)Loss of menin mediated by endothelial cells treated with CoPP is associated with increased maturation of adipocytesParathyroid hormone-responsive Smad3-related factor, Tmem119, promotes osteoblast differentiation and interacts with the bone morphogenetic protein-Runx2 pathwayDevelopment and optimization of a cell-based assay for the selection of synthetic compounds that potentiate bone morphogenetic protein-2 activity.MicroRNAs miR-26a, miR-26b, and miR-29b accelerate osteogenic differentiation of unrestricted somatic stem cells from human cord bloodOsteoblast menin regulates bone mass in vivo.Cyclin G2 suppresses estrogen-mediated osteogenesis through inhibition of Wnt/β-catenin signaling.Menin represses tumorigenesis via repressing cell proliferation.Impaired transforming growth factor-β (TGF-β) transcriptional activity and cell proliferation control of a menin in-frame deletion mutant associated with multiple endocrine neoplasia type 1 (MEN1).Role of osteoglycin in the linkage between muscle and bone.Post-surgical follow-up of primary hyperparathyroidism associated with multiple endocrine neoplasia type 1.Signaling networks that control the lineage commitment and differentiation of bone cells.Menin induces endodermal differentiation in aggregated P19 stem cells by modulating the retinoic acid receptors.Loss of menin in osteoblast lineage affects osteocyte-osteoclast crosstalk causing osteoporosisSignaling and transcriptional regulation in osteoblast commitment and differentiationTumor Suppressors and Endodermal Differentiation of P19 Embryonic Stem Cells.Dose-dependent effects of Runx2 on bone development.Multiple endocrine neoplasia type 1 (MEN1): not only inherited endocrine tumors.Segmental bone defects: from cellular and molecular pathways to the development of novel biological treatments.Menin and bone metabolism.Menin: a scaffold protein that controls gene expression and cell signaling.Molecular mechanisms of mesenchymal stem cell differentiation towards osteoblasts.Genetic mutations in sporadic pituitary adenomas--what to screen for?Twenty years of menin: emerging opportunities for restoration of transcription in MEN1.Gene clustering analysis in human osseous remodeling.A novel regulatory role for stromal-derived factor-1 signaling in bone morphogenic protein-2 osteogenic differentiation of mesenchymal C2C12 cells.Osteoblasts can induce dental pulp stem cells to undergo osteogenic differentiation.Expression and subcellular localization of menin in human cancer cells.Enhanced osteoprogenitor elongated collagen fiber matrix formation by bioactive glass ionic silicon dependent on Sp7 (osterix) transcription.SMAD2/SMAD3:SMAD4 heterotrimer regulates transcriptionThe future: genetics advances in MEN1 therapeutic approaches and management strategies.Lack of augmentation of tumor spectrum or severity in dual heterozygous Men1 and Rb1 knockout mice.MEN1 binds SMAD2/3:SMAD4 heterotrimerThe Induction of Bone Formation: The Translation Enigma.Multiple Endocrine Neoplasia Syndromes from Genetic and Epigenetic Perspectives.Smad5
P2860
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P248
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P2860
Menin is required for bone morphogenetic protein 2- and transforming growth factor beta-regulated osteoblastic differentiation through interaction with Smads and Runx2
description
2004 nî lūn-bûn
@nan
2004 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած
@hyw
2004 թվականի սեպտեմբերին հրատարակված գիտական հոդված
@hy
2004年の論文
@ja
2004年論文
@yue
2004年論文
@zh-hant
2004年論文
@zh-hk
2004年論文
@zh-mo
2004年論文
@zh-tw
2004年论文
@wuu
name
Menin is required for bone mor ...... teraction with Smads and Runx2
@ast
Menin is required for bone mor ...... teraction with Smads and Runx2
@en
Menin is required for bone mor ...... teraction with Smads and Runx2
@en-gb
Menin is required for bone mor ...... teraction with Smads and Runx2
@nl
type
label
Menin is required for bone mor ...... teraction with Smads and Runx2
@ast
Menin is required for bone mor ...... teraction with Smads and Runx2
@en
Menin is required for bone mor ...... teraction with Smads and Runx2
@en-gb
Menin is required for bone mor ...... teraction with Smads and Runx2
@nl
prefLabel
Menin is required for bone mor ...... teraction with Smads and Runx2
@ast
Menin is required for bone mor ...... teraction with Smads and Runx2
@en
Menin is required for bone mor ...... teraction with Smads and Runx2
@en-gb
Menin is required for bone mor ...... teraction with Smads and Runx2
@nl
P2093
P2860
P921
P356
P1476
Menin is required for bone mor ...... teraction with Smads and Runx2
@en
P2093
Geoffrey N Hendy
Hideaki Sowa
Hiroshi Kaji
Kazuo Chihara
Lucie Canaff
Toshihisa Komori
Toshitsugu Sugimoto
P2860
P304
P356
10.1074/JBC.M401312200
P407
P577
2004-09-24T00:00:00Z