Identification of the regulatory elements of the human von Willebrand factor for binding to platelet GPIb. Importance of structural integrity of the regions flanked by the CYS1272-CYS1458 disulfide bond

Identification of the regulatory elements of the human von Willebrand factor for binding to platelet GPIb. Importance of structural integrity of the regions flanked by the CYS1272-CYS1458 disulfide bond

Item
http://www.wikidata.org/entity/Q24293697
Functional display of platelet-binding VWF fragments on filamentous bacteriophagePlatelet GpIba binding to von Willebrand Factor under fluid shear:contributions of the D′D3-domain, A1-domain flanking peptide and O-linked glycans.O-linked glycosylation and functional incompatibility of porcine von Willebrand factor for human platelet GPIb receptors.Role of sialic acid for platelet life span: exposure of beta-galactose results in the rapid clearance of platelets from the circulation by asialoglycoprotein receptor-expressing liver macrophages and hepatocytes.Destabilization of the A1 domain in von Willebrand factor dissociates the A1A2A3 tri-domain and provokes spontaneous binding to glycoprotein Ibalpha and platelet activation under shear stressN-terminal flanking region of A1 domain in von Willebrand factor stabilizes structure of A1A2A3 complex and modulates platelet activation under shear stress.Shielding of the A1 domain by the D'D3 domains of von Willebrand factor modulates its interaction with platelet glycoprotein Ib-IX-V.A biophysical view on von Willebrand factor activation.Identification of amino acid residues responsible for von Willebrand factor binding to sulfatide by charged-to-alanine-scanning mutagenesis.Measurement of von Willebrand factor binding to a recombinant fragment of glycoprotein Ibalpha in an enzyme-linked immunosorbent assay-based method: performances in patients with type 2B von Willebrand disease
P2860

Identification of the regulatory elements of the human von Willebrand factor for binding to platelet GPIb. Importance of structural integrity of the regions flanked by the CYS1272-CYS1458 disulfide bond

Item
http://www.wikidata.org/entity/Q24293697
description
2002 nî lūn-bûn
@nan
2002 թուականի Յունիսին հրատարակուած գիտական յօդուած
@hyw
2002 թվականի հունիսին հրատարակված գիտական հոդված
@hy
2002年の論文
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2002年論文
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2002年論文
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2002年論文
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2002年論文
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2002年論文
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2002年论文
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name
Identification of the regulato ...... CYS1272-CYS1458 disulfide bond
@ast
Identification of the regulato ...... CYS1272-CYS1458 disulfide bond
@en
Identification of the regulato ...... CYS1272-CYS1458 disulfide bond
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type
label
Identification of the regulato ...... CYS1272-CYS1458 disulfide bond
@ast
Identification of the regulato ...... CYS1272-CYS1458 disulfide bond
@en
Identification of the regulato ...... CYS1272-CYS1458 disulfide bond
@nl
prefLabel
Identification of the regulato ...... CYS1272-CYS1458 disulfide bond
@ast
Identification of the regulato ...... CYS1272-CYS1458 disulfide bond
@en
Identification of the regulato ...... CYS1272-CYS1458 disulfide bond
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P1433
P1476
P2093
P2860
P304
P31
P356
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P698
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P1476
Identification of the regulato ...... CYS1272-CYS1458 disulfide bond
@en
P2093
P2860
P304
P31
P356
P407
P433
P478
P50
P577
P698