An intracellular serpin regulates necrosis by inhibiting the induction and sequelae of lysosomal injury
about
Anthranilate fluorescence marks a calcium-propagated necrotic wave that promotes organismal death in C. elegansAutomated high-content live animal drug screening using C. elegans expressing the aggregation prone serpin α1-antitrypsin ZA truncating mutation in SERPINB6 is associated with autosomal-recessive nonsyndromic sensorineural hearing lossSerpins flex their muscle: I. Putting the clamps on proteolysis in diverse biological systemsHsp70.1 and related lysosomal factors for necrotic neuronal deathThe atypical calpains: evolutionary analyses and roles in Caenorhabditis elegans cellular degenerationA pro-cathepsin L mutant is a luminal substrate for endoplasmic-reticulum-associated degradation in C. elegansHLA-F and MHC-I open conformers cooperate in a MHC-I antigen cross-presentation pathwaySerine protease activity contributes to control of Mycobacterium tuberculosis in hypoxic lung granulomas in miceThe glutaredoxin GLRX-21 functions to prevent selenium-induced oxidative stress in Caenorhabditis elegansSERPINA3K prevents oxidative stress induced necrotic cell death by inhibiting calcium overloadDistinct patterns of gene and protein expression elicited by organophosphorus pesticides in Caenorhabditis elegans.Vps-C complexes: gatekeepers of endolysosomal traffic.Osmotic regulation of Rab-mediated organelle dockingAnimal models of gastrointestinal and liver diseases. Animal models of necrotizing enterocolitis: pathophysiology, translational relevance, and challenges.Characterization of the renal cyst fluid proteome in autosomal dominant polycystic kidney disease (ADPKD) patients.Isolation of serpin-interacting proteins in C. elegans using protein affinity purification.Cell deathAutophagy protects C. elegans against necrosis during Pseudomonas aeruginosa infection.Insulin-like signaling determines survival during stress via posttranscriptional mechanisms in C. elegansA C. elegans model of human α1-antitrypsin deficiency links components of the RNAi pathway to misfolded protein turnoverInter-alpha inhibitor protein level in neonates predicts necrotizing enterocolitis.Serpin protease inhibitors in plant biology.Set-point control of RD21 protease activity by AtSerpin1 controls cell death in Arabidopsis.Genetic control of necrosis - another type of programmed cell death.Alternative cell death mechanisms in development and beyond.The biochemical and immunological characterization of two serpins from Clonorchis sinensis.RAB-5- and RAB-11-dependent vesicle-trafficking pathways are required for plasma membrane repair after attack by bacterial pore-forming toxin.Worms, flies and four-legged friends: the applicability of biological models to the understanding of intestinal inflammatory diseases.Using C. elegans to identify the protease targets of serpins in vivoModulatory profiling identifies mechanisms of small molecule-induced cell death.The aggregation-prone intracellular serpin SRP-2 fails to transit the ER in Caenorhabditis elegans.A blood fluke serine protease inhibitor regulates an endogenous larval elastase.The Effect of In Vitro Cultivation on the Transcriptome of Adult Brugia malayi.Bacillus thuringiensis Crystal Protein Cry6Aa Triggers Caenorhabditis elegans Necrosis Pathway Mediated by Aspartic Protease (ASP-1).Sensitive detection of lysosomal membrane permeabilization by lysosomal galectin puncta assay.Antibody Response to Serpin B13 Induces Adaptive Changes in Mouse Pancreatic Islets and Slows Down the Decline in the Residual Beta Cell Function in Children with Recent Onset of Type 1 Diabetes Mellitus.Anti-serpin antibody-mediated regulation of proteases in autoimmune diabetesHuman SERPINB12 Is an Abundant Intracellular Serpin Expressed in Most Surface and Glandular Epithelia.The genomic response of the retinal pigment epithelium to light damage and retinal detachment.
P2860
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P2860
An intracellular serpin regulates necrosis by inhibiting the induction and sequelae of lysosomal injury
description
2007 nî lūn-bûn
@nan
2007 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած
@hyw
2007 թվականի սեպտեմբերին հրատարակված գիտական հոդված
@hy
2007年の論文
@ja
2007年論文
@yue
2007年論文
@zh-hant
2007年論文
@zh-hk
2007年論文
@zh-mo
2007年論文
@zh-tw
2007年论文
@wuu
name
An intracellular serpin regula ...... d sequelae of lysosomal injury
@ast
An intracellular serpin regula ...... d sequelae of lysosomal injury
@en
An intracellular serpin regula ...... d sequelae of lysosomal injury
@en-gb
An intracellular serpin regula ...... d sequelae of lysosomal injury
@nl
type
label
An intracellular serpin regula ...... d sequelae of lysosomal injury
@ast
An intracellular serpin regula ...... d sequelae of lysosomal injury
@en
An intracellular serpin regula ...... d sequelae of lysosomal injury
@en-gb
An intracellular serpin regula ...... d sequelae of lysosomal injury
@nl
prefLabel
An intracellular serpin regula ...... d sequelae of lysosomal injury
@ast
An intracellular serpin regula ...... d sequelae of lysosomal injury
@en
An intracellular serpin regula ...... d sequelae of lysosomal injury
@en-gb
An intracellular serpin regula ...... d sequelae of lysosomal injury
@nl
P2093
P2860
P1433
P1476
An intracellular serpin regula ...... d sequelae of lysosomal injury
@en
P2093
Anne C Vetica
Cliff J Luke
David J Askew
Dieter Brömme
Donna B Stolz
Gary A Silverman
Gary L Moulder
Olivia S Long
Robert J Barstead
Shila M Nobar
P2860
P304
P356
10.1016/J.CELL.2007.07.013
P407
P577
2007-09-21T00:00:00Z