Cooperation of ERK and SCFSkp2 for MKP-1 destruction provides a positive feedback regulation of proliferating signaling - Wikidata - wikimedia - TriplyDB

Cooperation of ERK and SCFSkp2 for MKP-1 destruction provides a positive feedback regulation of proliferating signaling

Cooperation of ERK and SCFSkp2 for MKP-1 destruction provides a positive feedback regulation of proliferating signaling

http://www.wikidata.org/entity/Q24294827

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Substrate discrimination among mitogen-activated protein kinases through distinct docking sequence motifs Deregulated proteolysis by the F-box proteins SKP2 and beta-TrCP: tipping the scales of cancer Targeting the oncogenic E3 ligase Skp2 in prostate and breast cancer cells with a novel energy restriction-mimetic agent TLR4 signaling in effector CD4+ T cells regulates TCR activation and experimental colitis in mice Endotoxin conditioning induces VCP/p97-mediated and inducible nitric-oxide synthase-dependent Tyr284 nitration in protein phosphatase 2A.Crosstalk in inflammation: the interplay of glucocorticoid receptor-based mechanisms and kinases and phosphatases Mitogen-activated protein kinase phosphatase-1 (MKP-1) impairs the response to anti-epidermal growth factor receptor (EGFR) antibody cetuximab in metastatic colorectal cancer patients.S-adenosylmethionine regulates dual-specificity mitogen-activated protein kinase phosphatase expression in mouse and human hepatocytes.The MAP kinase phosphatase MKP-1 regulates BDNF-induced axon branching.Dual-specificity MAP kinase phosphatases (MKPs): shaping the outcome of MAP kinase signalling.Mitogen-activated protein kinase phosphatase-1 - a potential therapeutic target in metabolic disease.Ubiquitin-activating enzyme E1 inhibitor PYR41 attenuates angiotensin II-induced activation of dendritic cells via the IκBa/NF-κB and MKP1/ERK/STAT1 pathways.Analysis of mitogen-activated protein kinase activation and interactions with regulators and substrates Towards a quantitative representation of the cell signaling mechanisms of hallucinogens: measurement and mathematical modeling of 5-HT1A and 5-HT2A receptor-mediated ERK1/2 activation Prolonged proinflammatory cytokine production in monocytes modulated by interleukin 10 after influenza vaccination in older adults SKP2 cooperates with N-Ras or AKT to induce liver tumor development in mice.Activation of AMPKα2 in adipocytes is essential for nicotine-induced insulin resistance in vivo.Progesterone receptor inhibits proliferation of human breast cancer cells via induction of MAPK phosphatase 1 (MKP-1/DUSP1).The Caenorhabditis elegans replication licensing factor CDT-1 is targeted for degradation by the CUL-4/DDB-1 complex Skp2 is a promising therapeutic target in breast cancer.Cdt1 degradation to prevent DNA re-replication: conserved and non-conserved pathways.p38γ Mitogen-activated protein kinase signals through phosphorylating its phosphatase PTPH1 in regulating ras protein oncogenesis and stress response.Mitogen-activated protein kinase phosphatase (MKP)-1 in immunology, physiology, and disease.Diversity and specificity of the mitogen-activated protein kinase phosphatase-1 functions.Dual-specificity Phosphatase 1 Deficiency Induces Endometrioid Adenocarcinoma Progression via Activation of Mitogen-activated Protein Kinase/Extracellular Signal-regulated Kinase Pathway Acetylation of MKP-1 and the control of inflammation.Rewiring MAP kinases in Saccharomyces cerevisiae to regulate novel targets through ubiquitination KLF5 promotes breast cell survival partially through fibroblast growth factor-binding protein 1-pERK-mediated dual specificity MKP-1 protein phosphorylation and stabilization Regulation of JNK and p38 MAPK in the immune system: signal integration, propagation and termination.DUSP1 promoter methylation in peripheral blood leukocyte is associated with triple-negative breast cancer risk.Novel roles of Skp2 E3 ligase in cellular senescence, cancer progression, and metastasis.Mitogen-activated protein kinase phosphatase 1 as an inflammatory factor and drug target.Global gene expression analyses reveal changes in biological processes after hyperthermia in a rat glioma model.Mitogen-activated protein kinase phosphatase-1: function and regulation in bone and related tissues.An Analog-sensitive Version of the Protein Kinase Slt2 Allows Identification of Novel Targets of the Yeast Cell Wall Integrity Pathway.Mitogen-activated protein kinase phosphatase 1 (MKP-1) in macrophage biology and cardiovascular disease. A redox-regulated master controller of monocyte function and macrophage phenotype.AKT (v-akt murine thymoma viral oncogene homolog 1) and N-Ras (neuroblastoma ras viral oncogene homolog) coactivation in the mouse liver promotes rapid carcinogenesis by way of mTOR (mammalian target of rapamycin complex 1), FOXM1 (forkhead box M1)/Signal integration and coincidence detection in the mitogen-activated protein kinase/extracellular signal-regulated kinase (ERK) cascade: concomitant activation of receptor tyrosine kinases and of LRP-1 leads to sustained ERK phosphorylation via dow Distinct docking mechanisms mediate interactions between the Msg5 phosphatase and mating or cell integrity mitogen-activated protein kinases (MAPKs) in Saccharomyces cerevisiae Negative and positive regulation of MAPK phosphatase 3 controls platelet-derived growth factor-induced Erk activation.

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Cooperation of ERK and SCFSkp2 for MKP-1 destruction provides a positive feedback regulation of proliferating signaling

http://www.wikidata.org/entity/Q24294827

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2006 nî lūn-bûn

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2006 թուականի Յունուարին հրատարակուած գիտական յօդուած

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2006 թվականի հունվարին հրատարակված գիտական հոդված

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2006年の論文

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Cooperation of ERK and SCFSkp2 ...... ion of proliferating signaling

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Cooperation of ERK and SCFSkp2 ...... ion of proliferating signaling

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Cooperation of ERK and SCFSkp2 ...... ion of proliferating signaling

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Cooperation of ERK and SCFSkp2 ...... ion of proliferating signaling

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Cooperation of ERK and SCFSkp2 ...... ion of proliferating signaling

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Cooperation of ERK and SCFSkp2 ...... ion of proliferating signaling

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Cooperation of ERK and SCFSkp2 ...... ion of proliferating signaling

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Cooperation of ERK and SCFSkp2 ...... ion of proliferating signaling

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Cooperation of ERK and SCFSkp2 ...... ion of proliferating signaling

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Cooperation of ERK and SCFSkp2 ...... ion of proliferating signaling

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Cooperation of ERK and SCFSkp2 ...... ion of proliferating signaling

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Cooperation of ERK and SCFSkp2 ...... ion of proliferating signaling

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Journal of Biological Chemistry

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Cooperation of ERK and SCFSkp2 ...... ion of proliferating signaling

@en

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Jia-Ling Yang

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Yun-Wei Lin

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P2860

Reduced MAP kinase phosphatase-1 degradation after p42/p44MAPK-dependent phosphorylation

Oxidative stress and heat shock induce a human gene encoding a protein-tyrosine phosphatase

Meaningful relationships: the regulation of the Ras/Raf/MEK/ERK pathway by protein interactions

IEX-1: a new ERK substrate involved in both ERK survival activity and ERK activation

Role of the F-box protein Skp2 in lymphomagenesis

CDK inhibitors: positive and negative regulators of G1-phase progression

Specificity of receptor tyrosine kinase signaling: transient versus sustained extracellular signal-regulated kinase activation

SKP2 is required for ubiquitin-mediated degradation of the CDK inhibitor p27

Role of the SCFSkp2 ubiquitin ligase in the degradation of p21Cip1 in S phase

Mammalian MAP kinase signalling cascades

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915-26

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scholarly article

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4086242

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10.1074/JBC.M508720200

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2

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281

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2006-01-13T00:00:00Z

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16286470

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