Skp2 is a promising therapeutic target in breast cancer. - Wikidata - wikimedia - TriplyDB

Skp2 is a promising therapeutic target in breast cancer.

Skp2 is a promising therapeutic target in breast cancer.

http://www.wikidata.org/entity/Q35687208

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The Importance of Ubiquitin E3 Ligases, SCF and APC/C, in Human Cancers Xenohormetic and anti-aging activity of secoiridoid polyphenols present in extra virgin olive oil: a new family of gerosuppressant agents Inhibition of SKP2 Sensitizes Bromocriptine-Induced Apoptosis in Human Prolactinoma Cells Phosphorylation by mTORC1 stablizes Skp2 and regulates its oncogenic function in gastric cancer Prognostic impact of Jab1, p16, p21, p62, Ki67 and Skp2 in soft tissue sarcomas.The differential susceptibilities of MCF-7 and MDA-MB-231 cells to the cytotoxic effects of curcumin are associated with the PI3K/Akt-SKP2-Cip/Kips pathway.Curcumin suppresses cell growth and invasion and induces apoptosis by down-regulation of Skp2 pathway in glioma cells Targeting Jab1/CSN5 in nasopharyngeal carcinoma Salinomycin induces cell death via inactivation of Stat3 and downregulation of Skp2.Multiple molecular and cellular mechanisms of action of lycopene in cancer inhibition.Rottlerin exerts its anti-tumor activity through inhibition of Skp2 in breast cancer cells.Matrine derivative YF-18 inhibits lung cancer cell proliferation and migration through down-regulating Skp2.Acquisition of epithelial-mesenchymal transition is associated with Skp2 expression in paclitaxel-resistant breast cancer cells.Ubiquitination in disease pathogenesis and treatment.S-phase kinase-associated protein 2 promotes cell growth and motility in osteosarcoma cells.Prognosis genes in gastric adenocarcinoma identified by cross talk genes in disease‑related pathways The emerging roles of Jab1/CSN5 in cancer.Combined treatment with chrysin and 1,2,3,4,6-penta-O-galloyl-β-D-glucose synergistically inhibits LRP6 and Skp2 activation in triple-negative breast cancer and xenografts.Downregulation of Skp2 inhibits the growth and metastasis of gastric cancer cells in vitro and in vivo.p53, SKP2, and DKK3 as MYCN Target Genes and Their Potential Therapeutic Significance.Skp2 and its emerging role in the pathogenesis of systemic malignancies besides breast carcinomas.Paeoniflorin exerts antitumor effects by inactivating S phase kinase-associated protein 2 in glioma cells.Dysregulated expression of SKP2 and its role in hematological malignancies.Genistein inhibits the S-phase kinase-associated protein 2 expression in breast cancer cells.Skp2-dependent reactivation of AKT drives resistance to PI3K inhibitors.Anticancer and multidrug resistance-reversal effects of solanidine analogs synthetized from pregnadienolone acetate.F-box proteins involved in cancer-associated drug resistance.Crosstalk between ERα and Receptor Tyrosine Kinase Signalling and Implications for the Development of Anti-Endocrine Resistance.

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Skp2 is a promising therapeutic target in breast cancer.

http://www.wikidata.org/entity/Q35687208

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2012 nî lūn-bûn

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2012年の論文

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2012年論文

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2012年論文

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2012年論文

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2012年論文

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2012年論文

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2012年论文

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2012年论文

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2012年论文

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name

Skp2 is a promising therapeutic target in breast cancer.

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Skp2 is a promising therapeutic target in breast cancer.

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type

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Skp2 is a promising therapeutic target in breast cancer.

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Skp2 is a promising therapeutic target in breast cancer.

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prefLabel

Skp2 is a promising therapeutic target in breast cancer.

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Skp2 is a promising therapeutic target in breast cancer.

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P356

FONC.2011.00057

P1433

Frontiers in Oncology

P1476

Skp2 is a promising therapeutic target in breast cancer.

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P2093

Daming Gao

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Fazlul H Sarkar

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Hidefumi Fukushima

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Hiroyuki Inuzuka

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Lixin Wan

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Pengda Liu

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Wenyi Wei

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Zhiwei Wang

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P2860

Cooperation of ERK and SCFSkp2 for MKP-1 destruction provides a positive feedback regulation of proliferating signaling

Skp2B attenuates p53 function by inhibiting prohibitin

Oncogenic role of the ubiquitin ligase subunit Skp2 in human breast cancer

Phosphorylation by Akt1 promotes cytoplasmic localization of Skp2 and impairs APCCdh1-mediated Skp2 destruction

Skp2: a novel potential therapeutic target for prostate cancer

Clinical relevance of SKP2 alterations in metastatic melanoma

Phosphorylation-dependent regulation of cytosolic localization and oncogenic function of Skp2 by Akt/PKB

Control of cell growth by the SCF and APC/C ubiquitin ligases

Deregulated proteolysis by the F-box proteins SKP2 and beta-TrCP: tipping the scales of cancer

The predator becomes the prey: regulating the ubiquitin system by ubiquitylation and degradation

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scholarly article

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10.3389/FONC.2011.00057

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57

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1

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Fazlul H. Sarkar

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2012-01-01T00:00:00Z

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221779647

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22279619

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3263529

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