FGF-2 protects small cell lung cancer cells from apoptosis through a complex involving PKCepsilon, B-Raf and S6K2
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An siRNA screen identifies RSK1 as a key modulator of lung cancer metastasisDirect binding of integrin alphavbeta3 to FGF1 plays a role in FGF1 signalingIs the Canonical RAF/MEK/ERK Signaling Pathway a Therapeutic Target in SCLC?Cellular and molecular biology of small cell lung cancer: an overviewThe 1.65 Å resolution structure of the complex of AZD4547 with the kinase domain of FGFR1 displays exquisite molecular recognitionThe Startling Properties of Fibroblast Growth Factor 2: How to Exit Mammalian Cells without a Signal Peptide at HandTumor and host factors that may limit efficacy of chemotherapy in non-small cell and small cell lung cancerA novel requirement for Janus kinases as mediators of drug resistance induced by fibroblast growth factor-2 in human cancer cellsProtein kinase C isoforms: Multi-functional regulators of cell life and deathProtein Kinase C-ε Promotes EMT in Breast Cancer.Chlamydia trachomatis co-opts the FGF2 signaling pathway to enhance infectionFibroblast growth factor 2 causes G2/M cell cycle arrest in ras-driven tumor cells through a Src-dependent pathway.Chromatin-remodeling factors mediate the balance of sense-antisense transcription at the FGF2 locusHuR controls mitochondrial morphology through the regulation of BclxL translation.Large-scale screening identifies a novel microRNA, miR-15a-3p, which induces apoptosis in human cancer cell lines.S6 kinase 2 promotes breast cancer cell survival via Akt.Development of organometallic S6K1 inhibitors.Protein kinase C-epsilon activation induces mitochondrial dysfunction and fragmentation in renal proximal tubulesCrosstalk between KIT and FGFR3 Promotes Gastrointestinal Stromal Tumor Cell Growth and Drug ResistanceDysregulation of janus kinases and signal transducers and activators of transcription in cancer.Fibroblast Growth Factor Receptor 1 and Related Ligands in Small-Cell Lung CancerCancer-associated fibroblasts provide a suitable microenvironment for tumor development and progression in oral tongue squamous cancer.Basic fibroblast growth factor shows prognostic impact on survival in operable non-small cell lung cancer patientsTumor suppressor PDCD4 represses internal ribosome entry site-mediated translation of antiapoptotic proteins and is regulated by S6 kinase 2.Protein kinase Cepsilon makes the life and death decision.Protein kinase C as a stress sensor.S6Ks isoforms contribute to viability, migration, docetaxel resistance and tumor formation of prostate cancer cells.Development of monoclonal antibodies specific to ribosomal protein S6 kinase 2.Regulation of anti-apoptotic Bcl-2 family protein Mcl-1 by S6 kinase 2ERK8 is a novel HuR kinase that regulates tumour suppressor PDCD4 through a miR-21 dependent mechanismPhosphorylation of serine 779 in fibroblast growth factor receptor 1 and 2 by protein kinase C(epsilon) regulates Ras/mitogen-activated protein kinase signaling and neuronal differentiation.Protein kinase C epsilon: an oncogene and emerging tumor biomarker.Endothelial-derived FGF2 contributes to the progression of pulmonary hypertension in humans and rodents.Protein kinase Cepsilon: the mitochondria-mediated signaling pathway.Hyaluronan-CD44 interaction with protein kinase C(epsilon) promotes oncogenic signaling by the stem cell marker Nanog and the Production of microRNA-21, leading to down-regulation of the tumor suppressor protein PDCD4, anti-apoptosis, and chemotheraThe role of fibroblast growth factors in tumor growthTargeting fibroblast-growth-factor-receptor-dependent signaling for cancer therapy.Fibroblast growth factors and their receptors in cancer.S6K2: The Neglected S6 Kinase Family Member.The Multifunctional Protein Kinase C-ε in Cancer Development and Progression.
P2860
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P2860
FGF-2 protects small cell lung cancer cells from apoptosis through a complex involving PKCepsilon, B-Raf and S6K2
description
2006 nî lūn-bûn
@nan
2006 թուականի Յուլիսին հրատարակուած գիտական յօդուած
@hyw
2006 թվականի հուլիսին հրատարակված գիտական հոդված
@hy
2006年の論文
@ja
2006年論文
@yue
2006年論文
@zh-hant
2006年論文
@zh-hk
2006年論文
@zh-mo
2006年論文
@zh-tw
2006年论文
@wuu
name
FGF-2 protects small cell lung ...... ing PKCepsilon, B-Raf and S6K2
@ast
FGF-2 protects small cell lung ...... ing PKCepsilon, B-Raf and S6K2
@en
FGF-2 protects small cell lung ...... ing PKCepsilon, B-Raf and S6K2
@en-gb
FGF-2 protects small cell lung ...... ing PKCepsilon, B-Raf and S6K2
@nl
type
label
FGF-2 protects small cell lung ...... ing PKCepsilon, B-Raf and S6K2
@ast
FGF-2 protects small cell lung ...... ing PKCepsilon, B-Raf and S6K2
@en
FGF-2 protects small cell lung ...... ing PKCepsilon, B-Raf and S6K2
@en-gb
FGF-2 protects small cell lung ...... ing PKCepsilon, B-Raf and S6K2
@nl
prefLabel
FGF-2 protects small cell lung ...... ing PKCepsilon, B-Raf and S6K2
@ast
FGF-2 protects small cell lung ...... ing PKCepsilon, B-Raf and S6K2
@en
FGF-2 protects small cell lung ...... ing PKCepsilon, B-Raf and S6K2
@en-gb
FGF-2 protects small cell lung ...... ing PKCepsilon, B-Raf and S6K2
@nl
P2093
P2860
P50
P3181
P356
P1433
P1476
FGF-2 protects small cell lung ...... ing PKCepsilon, B-Raf and S6K2
@en
P2093
Frances Bowen
Ivan T Gout
Michael J Seckl
Muriel Aubert
Olivier E Pardo
Sally Davidson
Umme K Khanzada
P2860
P304
P3181
P356
10.1038/SJ.EMBOJ.7601198
P407
P50
P577
2006-06-29T00:00:00Z