Beyond the cell cycle: a new role for Cdk6 in differentiation
about
Cdk6-dependent regulation of G(1) length controls adult neurogenesisTDP-43 regulates retinoblastoma protein phosphorylation through the repression of cyclin-dependent kinase 6 expressionDifferential genomic targeting of the transcription factor TAL1 in alternate haematopoietic lineagesTargeting CDK6 in cancer: State of the art and new insightsA kinase-independent function of CDK6 links the cell cycle to tumor angiogenesisCooperation of DLC1 and CDK6 affects breast cancer clinical outcomeConditional deletion of the retinoblastoma (Rb) gene in ovarian granulosa cells leads to premature ovarian failure.Acquired CDK6 amplification promotes breast cancer resistance to CDK4/6 inhibitors and loss of ER signaling and dependence.Analysis of microRNA transcriptome by deep sequencing of small RNA libraries of peripheral bloodModulated expression of genes encoding estrogen metabolizing enzymes by G1-phase cyclin-dependent kinases 6 and 4 in human breast cancer cells.Forced expression of cyclin-dependent kinase 6 confers resistance of pro-B acute lymphocytic leukemia to Gleevec treatmentExpression of Fbxo7 in haematopoietic progenitor cells cooperates with p53 loss to promote lymphomagenesis.Interwoven roles of cyclin D3 and cdk4 recruited by ICP0 and ICP4 in the expression of herpes simplex virus genesRecurrent amplification at 7q21.2 Targets CDK6 gene in primary myxofibrosarcomas and identifies CDK6 overexpression as an independent adverse prognosticator.Cyclin-dependent kinase 6 phosphorylates NF-κB P65 at serine 536 and contributes to the regulation of inflammatory gene expression.MicroRNAs miR-26a, miR-26b, and miR-29b accelerate osteogenic differentiation of unrestricted somatic stem cells from human cord bloodUnexpected reduction of skin tumorigenesis on expression of cyclin-dependent kinase 6 in mouse epidermis.Mammalian cell-cycle regulation: several Cdks, numerous cyclins and diverse compensatory mechanisms.Regulation of CDK4miR-211 suppresses epithelial ovarian cancer proliferation and cell-cycle progression by targeting Cyclin D1 and CDK6.Inhibition of S-adenosylhomocysteine hydrolase decreases cell mobility and cell proliferation through cell cycle arrest.KSHV viral cyclin interferes with T-cell development and induces lymphoma through Cdk6 and Notch activation in vivoInhibition of cyclin-dependent kinase 6 suppresses cell proliferation and enhances radiation sensitivity in medulloblastoma cellsKnockdown of subunit 3 of the COP9 signalosome inhibits C2C12 myoblast differentiation via NF-KappaB signaling pathwayKinase requirements in human cells: II. Genetic interaction screens identify kinase requirements following HPV16 E7 expression in cancer cells.Differential regulation of cyclin-dependent kinase 4 (CDK4) and CDK6, evidence that CDK4 might not be activated by CDK7, and design of a CDK6 activating mutation.New insight into the role of miRNAs in leukemia.Let-7a functions as a tumor suppressor in Ewing's sarcoma cell lines partly by targeting cyclin-dependent kinase 6.DNA methylation-associated silencing of tumor-suppressor microRNAs in cancer.Identification of breast cancer mechanism based on weighted gene coexpression network analysis.Epigenetic silencing of MicroRNA miR-107 regulates cyclin-dependent kinase 6 expression in pancreatic cancer.Regulation of cyclin dependent kinase 6 by microRNA 124 in medulloblastoma.Single nucleotide polymorphism of hsa-miR-124a affects risk and prognosis of osteosarcoma.Methylation of miR-124a-1, miR-124a-2, and miR-124a-3 genes correlates with aggressive and advanced breast cancer disease.
P2860
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P2860
Beyond the cell cycle: a new role for Cdk6 in differentiation
description
2006 nî lūn-bûn
@nan
2006 թուականի Փետրուարին հրատարակուած գիտական յօդուած
@hyw
2006 թվականի փետրվարին հրատարակված գիտական հոդված
@hy
2006年の論文
@ja
2006年論文
@yue
2006年論文
@zh-hant
2006年論文
@zh-hk
2006年論文
@zh-mo
2006年論文
@zh-tw
2006年论文
@wuu
name
Beyond the cell cycle: a new role for Cdk6 in differentiation
@ast
Beyond the cell cycle: a new role for Cdk6 in differentiation
@en
Beyond the cell cycle: a new role for Cdk6 in differentiation
@en-gb
Beyond the cell cycle: a new role for Cdk6 in differentiation
@nl
type
label
Beyond the cell cycle: a new role for Cdk6 in differentiation
@ast
Beyond the cell cycle: a new role for Cdk6 in differentiation
@en
Beyond the cell cycle: a new role for Cdk6 in differentiation
@en-gb
Beyond the cell cycle: a new role for Cdk6 in differentiation
@nl
prefLabel
Beyond the cell cycle: a new role for Cdk6 in differentiation
@ast
Beyond the cell cycle: a new role for Cdk6 in differentiation
@en
Beyond the cell cycle: a new role for Cdk6 in differentiation
@en-gb
Beyond the cell cycle: a new role for Cdk6 in differentiation
@nl
P356
P1476
Beyond the cell cycle: a new role for Cdk6 in differentiation
@en
P2093
Martha J Grossel
Philip W Hinds
P304
P356
10.1002/JCB.20712
P407
P577
2006-02-15T00:00:00Z