about
Crystal structure of human CDK4 in complex with a D-type cyclinBrk/Protein tyrosine kinase 6 phosphorylates p27KIP1, regulating the activity of cyclin D-cyclin-dependent kinase 4CDK4 T172 phosphorylation is central in a CDK7-dependent bidirectional CDK4/CDK2 interplay mediated by p21 phosphorylation at the restriction pointKnockdown of cyclin-dependent kinase inhibitors induces cardiomyocyte re-entry in the cell cycleChimeras of p14ARF and p16: functional hybrids with the ability to arrest growthS phase entry causes homocysteine-induced death while ataxia telangiectasia and Rad3 related protein functions anti-apoptotically to protect neurons.Nucleolar GTP-binding Protein-1 (NGP-1) Promotes G1 to S Phase Transition by Activating Cyclin-dependent Kinase Inhibitor p21 Cip1/Waf1.The CDK4/CDK6 inhibitor PD0332991 paradoxically stabilizes activated cyclin D3-CDK4/6 complexes.Novel germline CDK4 mutations in patients with head and neck cancerAcetylation at lysine 346 controls the transforming activity of the HTLV-1 Tax oncoprotein in the Rat-1 fibroblast modelDifferential regulation of cyclin-dependent kinase 4 (CDK4) and CDK6, evidence that CDK4 might not be activated by CDK7, and design of a CDK6 activating mutation.Tspan5 is an independent favourable prognostic factor and suppresses tumour growth in gastric cancerSignaling through cyclin D-dependent kinases.FRK suppresses the proliferation of human glioma cells by inhibiting cyclin D1 nuclear accumulation.Establishment and characterization of a novel dedifferentiated liposarcoma cell line, NDDLS-1.The effect of SYT-SSX and extracellular signal-regulated kinase (ERK) on cell proliferation in synovial sarcoma.Cyclic AMP inhibits the proliferation of thyroid carcinoma cell lines through regulation of CDK4 phosphorylation.JNKs function as CDK4-activating kinases by phosphorylating CDK4 and p21.CDK4 phosphorylation status and a linked gene expression profile predict sensitivity to palbociclib.CDK4 IVS4-nt40 AA genotype and obesity-associated tumors/cancer in Italians - a case-control study.p27Kip1 inhibits cyclin D-cyclin-dependent kinase 4 by two independent modes.Mechanism of cell cycle entry mediated by the intrinsically disordered protein p27(Kip1).A suppressor screen in chlamydomonas identifies novel components of the retinoblastoma tumor suppressor pathway.Phosphorylation of cyclin dependent kinase 4 on tyrosine 17 is mediated by Src family kinases.Network-based modelling and percolation analysis of conformational dynamics and activation in the CDK2 and CDK4 proteins: dynamic and energetic polarization of the kinase lobes may determine divergence of the regulatory mechanisms.Dual Inhibition of CDK4 and CDK2 via Targeting p27 Tyrosine Phosphorylation Induces a Potent and Durable Response in Breast Cancer Cells.Formation of CDK4/6:CCND complexesCip/Kip CDK inhibitors bind CDK4/6:CCND complexesTranslokin (Cep57) interacts with cyclin D1 and prevents its nuclear accumulation in quiescent fibroblasts.Akt/p27kip1 Pathway Is Not Involved in Human Insulinoma Tumorigenesis.Imidazole Antifungal Drugs Inhibit the Cell Proliferation and Invasion of Human Breast Cancer Cells
P2860
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P2860
description
2006 nî lūn-bûn
@nan
2006 թուականի Նոյեմբերին հրատարակուած գիտական յօդուած
@hyw
2006 թվականի նոյեմբերին հրատարակված գիտական հոդված
@hy
2006年の論文
@ja
2006年論文
@yue
2006年論文
@zh-hant
2006年論文
@zh-hk
2006年論文
@zh-mo
2006年論文
@zh-tw
2006年论文
@wuu
name
Regulation of CDK4
@ast
Regulation of CDK4
@en
type
label
Regulation of CDK4
@ast
Regulation of CDK4
@en
prefLabel
Regulation of CDK4
@ast
Regulation of CDK4
@en
P2093
P2860
P356
P1433
P1476
Regulation of CDK4
@en
P2093
Hugues Kooken
Katia Coulonval
Laurence Bockstaele
Pierre P Roger
Sabine Paternot
P2860
P2888
P356
10.1186/1747-1028-1-25
P577
2006-11-08T00:00:00Z
P5875
P6179
1020594840