3-Aminopyrazole inhibitors of CDK2/cyclin A as antitumor agents. 1. Lead finding
about
Identifying tumor cell growth inhibitors by combinatorial chemistry and zebrafish assaysHit clustering can improve virtual fragment screening: CDK2 and PARP1 case studies.Selectivity and potency of cyclin-dependent kinase inhibitors.Cyclin Dependent Kinase 9 Inhibitors for Cancer TherapyKinase selectivity profiling by inhibitor affinity chromatography.Disruption of the EGFR E884-R958 ion pair conserved in the human kinome differentially alters signaling and inhibitor sensitivityHigh-throughput kinase profiling as a platform for drug discovery.Identification of inhibitors of the Leishmania cdc2-related protein kinase CRK3.1-Substituted carbamoyl and thiocarbamoyl-4,5-dihydro-1H-pyrazoles as possible cytotoxic and antimicrobial agents.Computer-aided design, synthesis and validation of 2-phenylquinazolinone fragments as CDK9 inhibitors with anti-HIV-1 Tat-mediated transcription activity.The importance of plasma protein binding in drug discovery.Prediction of Positions of Active Compounds Makes It Possible To Increase Activity in Fragment-Based Drug Development.The State of the Art in Azaborine Chemistry: New Synthetic Methods and Applications.Molecular modelling on small molecular CDK2 inhibitors: an integrated approach using a combination of molecular docking, 3D-QSAR and pharmacophore modelling.Characterization of CDK(5) inhibitor, 20-223 (aka CP668863) for colorectal cancer therapy.In vitro and in vivo pharmacodynamics of three novel antileishmanial lead series.Medicinal Chemistry Profiling of Monocyclic 1,2-Azaborines.Chemically induced degradation of CDK9 by a proteolysis targeting chimera (PROTAC).
P2860
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P2860
3-Aminopyrazole inhibitors of CDK2/cyclin A as antitumor agents. 1. Lead finding
description
2004 nî lūn-bûn
@nan
2004 թուականի Յունիսին հրատարակուած գիտական յօդուած
@hyw
2004 թվականի հունիսին հրատարակված գիտական հոդված
@hy
2004年の論文
@ja
2004年論文
@yue
2004年論文
@zh-hant
2004年論文
@zh-hk
2004年論文
@zh-mo
2004年論文
@zh-tw
2004年论文
@wuu
name
3-Aminopyrazole inhibitors of CDK2/cyclin A as antitumor agents. 1. Lead finding
@ast
3-Aminopyrazole inhibitors of CDK2/cyclin A as antitumor agents. 1. Lead finding
@en
3-Aminopyrazole inhibitors of CDK2/cyclin A as antitumor agents. 1. Lead finding
@en-gb
3-Aminopyrazole inhibitors of CDK2/cyclin A as antitumor agents. 1. Lead finding
@nl
type
label
3-Aminopyrazole inhibitors of CDK2/cyclin A as antitumor agents. 1. Lead finding
@ast
3-Aminopyrazole inhibitors of CDK2/cyclin A as antitumor agents. 1. Lead finding
@en
3-Aminopyrazole inhibitors of CDK2/cyclin A as antitumor agents. 1. Lead finding
@en-gb
3-Aminopyrazole inhibitors of CDK2/cyclin A as antitumor agents. 1. Lead finding
@nl
prefLabel
3-Aminopyrazole inhibitors of CDK2/cyclin A as antitumor agents. 1. Lead finding
@ast
3-Aminopyrazole inhibitors of CDK2/cyclin A as antitumor agents. 1. Lead finding
@en
3-Aminopyrazole inhibitors of CDK2/cyclin A as antitumor agents. 1. Lead finding
@en-gb
3-Aminopyrazole inhibitors of CDK2/cyclin A as antitumor agents. 1. Lead finding
@nl
P2093
P50
P356
P1476
3-Aminopyrazole inhibitors of CDK2/cyclin A as antitumor agents. 1. Lead finding
@en
P2093
Antonella Isacchi
Aurelio Marsiglio
Betsy S Pierce
Claudia Piutti
Edward L Fritzen
Elena Casale
Enrico Pesenti
Francesco Fiorentini
Fulvia Roletto
Gabriella Traquandi
P304
P356
10.1021/JM031145U
P407
P577
2004-06-17T00:00:00Z