Disruption of the EGFR E884-R958 ion pair conserved in the human kinome differentially alters signaling and inhibitor sensitivity
about
Mechanisms of drug resistance in kinases.MET-independent lung cancer cells evading EGFR kinase inhibitors are therapeutically susceptible to BH3 mimetic agentsOncogenic potential is related to activating effect of cancer single and double somatic mutations in receptor tyrosine kinasesTranscript profiling in M. truncatula lss and sunn-1 mutants reveals different expression profiles despite disrupted SUNN gene function in both mutants.Cancer genes in lung cancer: racial disparities: are there any?Novel EPHB4 Receptor Tyrosine Kinase Mutations and Kinomic Pathway Analysis in Lung CancerGlobal connectivity of hub residues in Oncoprotein structures encodes genetic factors dictating personalized drug response to targeted Cancer therapy.Transcriptomic-metabolomic reprogramming in EGFR-mutant NSCLC early adaptive drug escape linking TGFβ2-bioenergetics-mitochondrial priming.Two cases of leptomeningeal metastases from lung adenocarcinoma which progressed during gefitinib therapy but responded to erlotinib.The impact of rare EGFR mutations on the treatment response of patients with non-small cell lung cancer.
P2860
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P2860
Disruption of the EGFR E884-R958 ion pair conserved in the human kinome differentially alters signaling and inhibitor sensitivity
description
2008 nî lūn-bûn
@nan
2008年の論文
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2008年学术文章
@wuu
2008年学术文章
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2008年学术文章
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2008年学术文章
@zh-my
2008年学术文章
@zh-sg
2008年學術文章
@yue
2008年學術文章
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2008年學術文章
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name
Disruption of the EGFR E884-R9 ...... ling and inhibitor sensitivity
@en
Disruption of the EGFR E884-R9 ...... ing and inhibitor sensitivity.
@nl
type
label
Disruption of the EGFR E884-R9 ...... ling and inhibitor sensitivity
@en
Disruption of the EGFR E884-R9 ...... ing and inhibitor sensitivity.
@nl
prefLabel
Disruption of the EGFR E884-R9 ...... ling and inhibitor sensitivity
@en
Disruption of the EGFR E884-R9 ...... ing and inhibitor sensitivity.
@nl
P2093
P2860
P356
P1433
P1476
Disruption of the EGFR E884-R9 ...... ling and inhibitor sensitivity
@en
P2093
A El-Telbany
J G Christensen
K Kawahara
K Nakagawa
P2860
P2888
P304
P356
10.1038/ONC.2008.411
P407
P577
2008-11-17T00:00:00Z
P5875
P6179
1020878505