Daxx silencing sensitizes cells to multiple apoptotic pathways
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Release of RASSF1C from the nucleus by Daxx degradation links DNA damage and SAPK/JNK activationEvidence for a role of the cellular ND10 protein PML in mediating intrinsic immunity against human cytomegalovirus infectionsDaxx is reciprocally regulated by Mdm2 and HauspFTH1 binds to Daxx and inhibits Daxx-mediated cell apoptosisNegative regulation of p53 functions by Daxx and the involvement of MDM2Inactivating a cellular intrinsic immune defense mediated by Daxx is the mechanism through which the human cytomegalovirus pp71 protein stimulates viral immediate-early gene expressionIridovirus CARD Protein Inhibits Apoptosis through Intrinsic and Extrinsic PathwaysSubcellular localization of Daxx determines its opposing functions in ischemic cell deathDepletion of the adaptor protein NCK increases UV-induced p53 phosphorylation and promotes apoptosis.DAXX interacts with phage PhiC31 integrase and inhibits recombination.Mutant p53 disrupts the stress MAPK activation circuit induced by ASK1-dependent stabilization of Daxx.Mutations in the M112/M113-coding region facilitate murine cytomegalovirus replication in human cells.FLASH knockdown sensitizes cells to Fas-mediated apoptosis via down-regulation of the anti-apoptotic proteins, MCL-1 and Cflip shortDegradation of MDM2 by the interaction between berberine and DAXX leads to potent apoptosis in MDM2-overexpressing cancer cells.DNA damage-induced regulatory interplay between DAXX, p53, ATM kinase and Wip1 phosphatase.Evidence for a dual antiviral role of the major nuclear domain 10 component Sp100 during the immediate-early and late phases of the human cytomegalovirus replication cycleDeath-associated protein 6 (Daxx) mediates cAMP-dependent stimulation of Cyp11a1 (P450scc) transcriptionMethylation of RASSF1A gene promoter is regulated by p53 and DAXX.Daxx represses RelB target promoters via DNA methyltransferase recruitment and DNA hypermethylationThe SUMO ligase PIAS1 regulates UV-induced apoptosis by recruiting Daxx to SUMOylated foci.Daxx upregulation within the cytoplasm of reovirus-infected cells is mediated by interferon and contributes to apoptosis.Death domain-associated protein DAXX promotes ovarian cancer development and chemoresistance.Self-regulatory role of 4-hydroxynonenal in signaling for stress-induced programmed cell death.Stress-dependent Daxx-CHIP interaction suppresses the p53 apoptotic program.Dynamics of histone H3.3 deposition in proliferating and senescent cells reveals a DAXX-dependent targeting to PML-NBs important for pericentromeric heterochromatin organization.Lipid mediators in the neural cell nucleus: their metabolism, signaling, and association with neurological disorders.DAXX modulates human papillomavirus early gene expression and genome replication in U2OS cells.A role for eukaryotic initiation factor 4B overexpression in the pathogenesis of diffuse large B-cell lymphoma.Daxx is a transcriptional repressor of CCAAT/enhancer-binding protein betaA novel dual signaling axis for NSP 5a3a induced apoptosis in head and neck carcinoma.Mechanisms of 4-hydroxy-2-nonenal induced pro- and anti-apoptotic signaling.Daxx inhibits stress-induced apoptosis in cardiac myocytes.Histone deacetylase 7 promotes PML sumoylation and is essential for PML nuclear body formation4-Hydroxynonenal self-limits fas-mediated DISC-independent apoptosis by promoting export of Daxx from the nucleus to the cytosol and its binding to Fas.Human cytomegalovirus gene expression is silenced by Daxx-mediated intrinsic immune defense in model latent infections established in vitro.Gene expression pattern in apoptotic QGY-7703 cells induced by homoharringtonine.HGF/SF regulates expression of apoptotic genes in MCF-10A human mammary epithelial cells.Human cytomegalovirus (HCMV) UL82 gene product (pp71) relieves hDaxx-mediated repression of HCMV replication.The transcriptional repressor hDaxx potentiates p53-dependent apoptosis.Nuclear domain 10 components promyelocytic leukemia protein and hDaxx independently contribute to an intrinsic antiviral defense against human cytomegalovirus infection.
P2860
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P2860
Daxx silencing sensitizes cells to multiple apoptotic pathways
description
2003 nî lūn-bûn
@nan
2003 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2003 թվականի հոտեմբերին հրատարակված գիտական հոդված
@hy
2003年の論文
@ja
2003年論文
@yue
2003年論文
@zh-hant
2003年論文
@zh-hk
2003年論文
@zh-mo
2003年論文
@zh-tw
2003年论文
@wuu
name
Daxx silencing sensitizes cells to multiple apoptotic pathways
@ast
Daxx silencing sensitizes cells to multiple apoptotic pathways
@en
Daxx silencing sensitizes cells to multiple apoptotic pathways
@en-gb
Daxx silencing sensitizes cells to multiple apoptotic pathways
@nl
type
label
Daxx silencing sensitizes cells to multiple apoptotic pathways
@ast
Daxx silencing sensitizes cells to multiple apoptotic pathways
@en
Daxx silencing sensitizes cells to multiple apoptotic pathways
@en-gb
Daxx silencing sensitizes cells to multiple apoptotic pathways
@nl
prefLabel
Daxx silencing sensitizes cells to multiple apoptotic pathways
@ast
Daxx silencing sensitizes cells to multiple apoptotic pathways
@en
Daxx silencing sensitizes cells to multiple apoptotic pathways
@en-gb
Daxx silencing sensitizes cells to multiple apoptotic pathways
@nl
P2860
P1476
Daxx silencing sensitizes cells to multiple apoptotic pathways
@en
P2093
J Don Chen
Liuh-Yow Chen
P2860
P304
P356
10.1128/MCB.23.20.7108-7121.2003
P407
P577
2003-10-01T00:00:00Z